Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NLY75_RS09765 Genome accession   NZ_CP100432
Coordinates   1918645..1919367 (-) Length   240 a.a.
NCBI ID   WP_023371484.1    Uniprot ID   -
Organism   Streptococcus suis T15     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1913645..1924367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY75_RS09745 (NLY75_09745) - 1913790..1915013 (-) 1224 WP_023371478.1 cysteine desulfurase -
  NLY75_RS09750 (NLY75_09750) sufD 1915017..1916279 (-) 1263 WP_023371480.1 Fe-S cluster assembly protein SufD -
  NLY75_RS09755 (NLY75_09755) sufC 1916296..1917069 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  NLY75_RS09760 (NLY75_09760) - 1917476..1918648 (-) 1173 WP_023371482.1 MraY family glycosyltransferase -
  NLY75_RS09765 (NLY75_09765) mecA 1918645..1919367 (-) 723 WP_023371484.1 adaptor protein MecA Regulator
  NLY75_RS09770 (NLY75_09770) - 1919495..1920331 (-) 837 WP_023371486.1 undecaprenyl-diphosphate phosphatase -
  NLY75_RS09775 (NLY75_09775) - 1920458..1922023 (+) 1566 WP_023371488.1 ABC transporter substrate-binding protein/permease -
  NLY75_RS09780 (NLY75_09780) - 1922016..1922759 (+) 744 WP_023371490.1 amino acid ABC transporter ATP-binding protein -
  NLY75_RS09785 (NLY75_09785) - 1922883..1923092 (-) 210 WP_009910800.1 hypothetical protein -
  NLY75_RS09790 (NLY75_09790) - 1923178..1924080 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28000.49 Da        Isoelectric Point: 3.9704

>NTDB_id=705333 NLY75_RS09765 WP_023371484.1 1918645..1919367(-) (mecA) [Streptococcus suis T15]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGYYYLTVLINVENRSKQYPGYILSRMLEFTNDTELTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=705333 NLY75_RS09765 WP_023371484.1 1918645..1919367(-) (mecA) [Streptococcus suis T15]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTTATTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCTAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTGAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACGGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471