Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NLY76_RS08770 Genome accession   NZ_CP100430
Coordinates   1801269..1801991 (-) Length   240 a.a.
NCBI ID   WP_044686889.1    Uniprot ID   A0A0Z8L625
Organism   Streptococcus suis strain LSS42     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1796269..1806991
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY76_RS08750 (NLY76_08750) - 1796270..1797493 (-) 1224 WP_015647356.1 cysteine desulfurase -
  NLY76_RS08755 (NLY76_08755) sufD 1797497..1798759 (-) 1263 WP_024389052.1 Fe-S cluster assembly protein SufD -
  NLY76_RS08760 (NLY76_08760) sufC 1798776..1799549 (-) 774 WP_044769974.1 Fe-S cluster assembly ATPase SufC -
  NLY76_RS08765 (NLY76_08765) - 1800100..1801272 (-) 1173 WP_002938168.1 glycosyltransferase family 4 protein -
  NLY76_RS08770 (NLY76_08770) mecA 1801269..1801991 (-) 723 WP_044686889.1 adaptor protein MecA Regulator
  NLY76_RS08775 (NLY76_08775) - 1802119..1802955 (-) 837 WP_024395368.1 undecaprenyl-diphosphate phosphatase -
  NLY76_RS08780 (NLY76_08780) - 1803082..1804647 (+) 1566 WP_044686888.1 ABC transporter substrate-binding protein/permease -
  NLY76_RS08785 (NLY76_08785) - 1804640..1805383 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  NLY76_RS08790 (NLY76_08790) - 1805507..1805716 (-) 210 WP_009910800.1 hypothetical protein -
  NLY76_RS08795 (NLY76_08795) - 1805802..1806704 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27972.57 Da        Isoelectric Point: 4.0987

>NTDB_id=705225 NLY76_RS08770 WP_044686889.1 1801269..1801991(-) (mecA) [Streptococcus suis strain LSS42]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIKDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=705225 NLY76_RS08770 WP_044686889.1 1801269..1801991(-) (mecA) [Streptococcus suis strain LSS42]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGCCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAAAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCGGTAGAAGAATCGGAATTATATAAAATGGATGGTCATTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCTAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8L625

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471