Detailed information NTG0705217

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: NLY76_RS06035
• Genome accession: NZ_CP100430
• Coordinates: 1255497..1257734 (-)
• Length: 745 a.a.
• NCBI ID: WP_024389357.1
• Uniprot ID: A0AB33UGP1
• Organism: Streptococcus suis strain LSS42
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1250497..1262734

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY76_RS06005 (NLY76_06005)	tmk	1250602..1251240 (-)	639	WP_015646956.1	dTMP kinase	-
NLY76_RS06010 (NLY76_06010)	-	1251415..1252281 (+)	867	WP_015646957.1	YitT family protein	-
NLY76_RS06015 (NLY76_06015)	-	1252318..1253589 (-)	1272	WP_015646958.1	toxic anion resistance protein	-
NLY76_RS06020 (NLY76_06020)	-	1253595..1254422 (-)	828	WP_044770262.1	hypothetical protein	-
NLY76_RS06025 (NLY76_06025)	-	1254516..1255172 (-)	657	WP_024396040.1	CBS domain-containing protein	-
NLY76_RS06030 (NLY76_06030)	-	1255355..1255480 (-)	126	Protein_1143	IS982 family transposase	-
NLY76_RS06035 (NLY76_06035)	comEC/celB	1255497..1257734 (-)	2238	WP_024389357.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NLY76_RS06040 (NLY76_06040)	comEA/celA/cilE	1257718..1258380 (-)	663	WP_014638159.1	helix-hairpin-helix domain-containing protein	Machinery gene
NLY76_RS06045 (NLY76_06045)	-	1258447..1259193 (-)	747	WP_014638160.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
NLY76_RS06050 (NLY76_06050)	-	1259340..1260785 (+)	1446	WP_044686700.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
NLY76_RS06055 (NLY76_06055)	-	1261200..1261985 (+)	786	WP_044770261.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84012.81 Da
• Isoelectric Point: 6.9058

>NTDB_id=705217 NLY76_RS06035 WP_024389357.1 1255497..1257734(-) (comEC/celB) [Streptococcus suis strain LSS42]
MSRSIKLPCQPIHLAVLAVAVYFAVHSFSLLTMGLLSLILAVFGVRQGKTVFLKTLPLLALCGLFFGCQKVQWERADQSA
PEQVTTVQVIPDTIEVSGDSLSFRGWADGQTYQVFYKLASQEEQTYFQELTDLVQLDVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPILMTYFYAFQPLSILLTFVFSFIFDVLLLPGLSV
IFLLSPIIKITWVNGFFVFMEKIIVWVADLGFRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSQGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=705217 NLY76_RS06035 WP_024389357.1 1255497..1257734(-) (comEC/celB) [Streptococcus suis strain LSS42]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCAGTCTTGGCGGTGGCAGTTTACTTTGCAGTCCATTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGATATTAGCTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTTCTCA
AAACGCTGCCGCTTCTAGCCTTATGTGGTCTGTTTTTCGGATGCCAGAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAACAAGTCACAACTGTTCAGGTCATTCCAGATACCATTGAAGTCAGCGGGGACAGCCTGTCCTTTCGTGGTTGGGC
TGACGGACAAACCTATCAGGTGTTTTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAGAGCTGACTGATCTGG
TCCAGCTAGATGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGACTATCAGGCCTATCTG
AAAACACAGGGTATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTCGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGATTCTCATGACCTATTTCTATG
CCTTCCAGCCCTTGTCTATTCTCTTGACTTTTGTCTTTTCCTTTATCTTTGATGTCCTGCTCTTGCCAGGCTTGTCGGTC
ATTTTTCTCTTATCACCAATTATCAAGATTACCTGGGTCAACGGATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCGGATTTGGGCTTTCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGTCGGGTCGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACGCACACCGATACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCAGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGATCGCTTGCCAATTTTTGACT
CCTATCTGGAAGTCCTCTATCCAGATGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGATCCAAAGGTTCTTCCTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCTC
TGGTATCTGCTGGAGAAAATAACCGCTACAAGCACCCTCACCAAGAAACCTTGGACCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGGGCAATCCGCTTCCGAGGCTGGAAGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (215-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.324	99.329	0.54
comEC/celB	Streptococcus mitis NCTC 12261	53.469	98.658	0.528
comEC/celB	Streptococcus pneumoniae TIGR4	52.582	98.792	0.519
comEC/celB	Streptococcus pneumoniae Rx1	52.31	98.792	0.517
comEC/celB	Streptococcus pneumoniae D39	52.31	98.792	0.517
comEC/celB	Streptococcus pneumoniae R6	52.31	98.792	0.517
comEC	Lactococcus lactis subsp. cremoris KW2	48.728	100	0.489