Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NLY76_RS00345 Genome accession   NZ_CP100430
Coordinates   57059..57958 (+) Length   299 a.a.
NCBI ID   WP_044686821.1    Uniprot ID   A0A116KIR3
Organism   Streptococcus suis strain LSS42     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 52059..62958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY76_RS00315 (NLY76_00315) - 52263..53033 (+) 771 WP_044686820.1 membrane protein -
  NLY76_RS10570 - 53036..54740 (+) 1705 Protein_43 ABC transporter ATP-binding protein -
  NLY76_RS00330 (NLY76_00330) - 54841..55014 (+) 174 WP_015646236.1 hypothetical protein -
  NLY76_RS00335 (NLY76_00335) ruvB 55262..56263 (+) 1002 WP_004195448.1 Holliday junction branch migration DNA helicase RuvB -
  NLY76_RS00340 (NLY76_00340) - 56331..56954 (+) 624 WP_044769929.1 HAD-IA family hydrolase -
  NLY76_RS00345 (NLY76_00345) comR 57059..57958 (+) 900 WP_044686821.1 helix-turn-helix domain-containing protein Regulator
  NLY76_RS00350 (NLY76_00350) - 58166..59386 (+) 1221 WP_044769931.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  NLY76_RS00355 (NLY76_00355) - 59577..61100 (+) 1524 WP_044769932.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35089.97 Da        Isoelectric Point: 4.5731

>NTDB_id=705182 NLY76_RS00345 WP_044686821.1 57059..57958(+) (comR) [Streptococcus suis strain LSS42]
MNDKEFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKQKYEVND
LLIIRLQLEYVRLSSSDSEIFGQFLKIIEYLHGQIDIINSSDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVNKDRGGAEKHYLDAMLFAKLIENRELEQKIEEDWKVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=705182 NLY76_RS00345 WP_044686821.1 57059..57958(+) (comR) [Streptococcus suis strain LSS42]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTATCCTTGCCAGAAAGATACTCCAAGCTGAAA
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGATGCTATCATGACGGAAATCTATGA
TGATTATTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCCCGAATTGATACCTTAGAGTCAG
GGACAGCAGGCTTTGGAAAAGAGATACTGGAAGATTACTTTGAACAAATTTTCCGAAAACAAAAGTACGAAGTGAATGAT
TTGCTGATTATTAGGCTCCAGCTTGAATACGTTAGATTGTCCAGTAGTGACTCAGAAATATTTGGACAGTTTTTGAAAAT
TATAGAATATTTACATGGACAAATTGATATTATCAATTCAAGTGATTTATTTGTTCTAAGAGATACATTGTTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTATGAACCAATACCAAAGATATTCGACAGTGTAGATAAAATTATACAGTCAACG
CAAGATTTTCAGAAAAAGCCAATTGTCAGTGTGTTGAAATGGAAGTATGCACTTTTTGTAAATAAGGATAGAGGTGGGGC
TGAAAAGCATTATCTAGATGCGATGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAGCAGAAGATTGAAGAAGATT
GGAAAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116KIR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis 05ZYH33

92.642

100

0.926
  comR Streptococcus suis P1/7

92.642

100

0.926
  comR Streptococcus suis D9

59.801

100

0.602
  comR Streptococcus mutans UA159

44.816

100

0.448
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.801

97.324

0.368
  comR Streptococcus pyogenes MGAS315

37.037

99.331

0.368