Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NKZ81_RS09775 Genome accession   NZ_CP100328
Coordinates   1948939..1949661 (-) Length   240 a.a.
NCBI ID   WP_024417838.1    Uniprot ID   -
Organism   Streptococcus suis strain STC86     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1943939..1954661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NKZ81_RS09755 (NKZ81_09755) - 1944010..1945236 (-) 1227 WP_002938158.1 cysteine desulfurase -
  NKZ81_RS09760 (NKZ81_09760) sufD 1945238..1946500 (-) 1263 WP_024417839.1 Fe-S cluster assembly protein SufD -
  NKZ81_RS09765 (NKZ81_09765) sufC 1946517..1947290 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  NKZ81_RS09770 (NKZ81_09770) - 1947770..1948942 (-) 1173 WP_002938168.1 glycosyltransferase family 4 protein -
  NKZ81_RS09775 (NKZ81_09775) mecA 1948939..1949661 (-) 723 WP_024417838.1 adaptor protein MecA Regulator
  NKZ81_RS09780 (NKZ81_09780) - 1949789..1950625 (-) 837 WP_024417837.1 undecaprenyl-diphosphate phosphatase -
  NKZ81_RS09785 (NKZ81_09785) - 1950752..1952317 (+) 1566 WP_024393418.1 ABC transporter substrate-binding protein/permease -
  NKZ81_RS09790 (NKZ81_09790) - 1952310..1953053 (+) 744 WP_024393419.1 amino acid ABC transporter ATP-binding protein -
  NKZ81_RS09795 (NKZ81_09795) - 1953181..1953390 (-) 210 WP_009910800.1 hypothetical protein -
  NKZ81_RS09800 (NKZ81_09800) - 1953476..1954378 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27999.60 Da        Isoelectric Point: 4.0987

>NTDB_id=704350 NKZ81_RS09775 WP_024417838.1 1948939..1949661(-) (mecA) [Streptococcus suis strain STC86]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIKDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=704350 NKZ81_RS09775 WP_024417838.1 1948939..1949661(-) (mecA) [Streptococcus suis strain STC86]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATATTTGTTACCAAATCTGATTTG
GATCAGAACTTGAATTTTGATGAATTTACAGATTTGTCGGAACTCGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAAAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCATTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCTAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

52.049

100

0.529
  mecA Streptococcus pneumoniae D39

52.049

100

0.529
  mecA Streptococcus pneumoniae R6

52.049

100

0.529
  mecA Streptococcus pneumoniae TIGR4

52.049

100

0.529
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471