Detailed information    

insolico Bioinformatically predicted

Overview

Name   xerS   Type   Machinery gene
Locus tag   H7674_RS04680 Genome accession   NZ_AP023388
Coordinates   931947..933017 (+) Length   356 a.a.
NCBI ID   WP_023079834.1    Uniprot ID   Q48TG2
Organism   Streptococcus pyogenes strain NIH35     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 926947..938017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7674_RS04660 (SPNIH35_08690) - 927939..928637 (+) 699 WP_002989743.1 GntR family transcriptional regulator -
  H7674_RS04665 (SPNIH35_08700) - 928735..929067 (+) 333 WP_002989745.1 putative DNA-binding protein -
  H7674_RS04670 (SPNIH35_08710) ffh 929082..930644 (+) 1563 WP_021340793.1 signal recognition particle protein -
  H7674_RS04675 (SPNIH35_08720) - 930779..931477 (-) 699 WP_002993300.1 XRE family transcriptional regulator -
  H7674_RS04680 (SPNIH35_08730) xerS 931947..933017 (+) 1071 WP_023079834.1 tyrosine recombinase XerS Machinery gene
  H7674_RS04685 (SPNIH35_08740) - 933716..934198 (+) 483 WP_002984600.1 PASTA domain-containing protein -
  H7674_RS04690 (SPNIH35_08750) citC 934287..935339 (+) 1053 WP_011284808.1 [citrate (pro-3S)-lyase] ligase -
  H7674_RS04695 (SPNIH35_08760) - 935449..936843 (-) 1395 WP_014635474.1 oxaloacetate decarboxylase subunit alpha -
  H7674_RS04700 (SPNIH35_08770) citX 936858..937436 (-) 579 WP_011054513.1 citrate lyase holo-[acyl-carrier protein] synthase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41457.54 Da        Isoelectric Point: 9.5552

>NTDB_id=70376 H7674_RS04680 WP_023079834.1 931947..933017(+) (xerS) [Streptococcus pyogenes strain NIH35]
MRRELLLEKIETYKAVMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLE
AFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=70376 H7674_RS04680 WP_023079834.1 931947..933017(+) (xerS) [Streptococcus pyogenes strain NIH35]
ATGAGACGCGAATTATTACTAGAAAAAATTGAAACCTACAAGGCTGTCATGCCTTGGTATGTTTTAGATTATTACCAATC
CAAATTAGCTGTTCCATACAGCTTTACCACCTTATATGAGTATTTAAAAGAATACAAACGCTTTTTTGATTGGCTGATGG
ATGCTGATTTAACGCAGGCGCCAAAGATTGCTGATATTGACTTGAGCACGCTTGAGCACCTTACCAAGAAGGATTTAGAG
GCCTTTGTGCTTTATTTGCGGGAACGACCTTCTCTCAACACCTATTCCACCAAAGAGGGGCTTTCTCAAACCACTATTAA
TCGGACCTTGTCTGCCTTATCAAGCCTTTACAAGTACTTGACTGAAGAGGTTGAAAATGACCAAGGGGAGCCTTATTTTT
ATCGGAATGTTATGAAAAAAGTGTCAACAAAAAAGAAAAAAGAAACCCTGGCCTCCAGAGCGGAAAATATTAAGCAGAAA
CTGTTTTTAGGTGATGAAACTCTAGCTTTCTTGGATTATGTGGATAAGGAATATGAGCAAAAATTGTCTAATCGTGCCAA
ATCTTCTTTCCGTAAAAATAAGGAGAGGGATTTGGCTATTATTGCTCTACTACTTGCTTCTGGTGTTCGTTTGTCTGAAG
CAGTGAATCTTGATTTAAAAGATGTCAATCTAAATATGATGATTATCGAAGTTATTCGCAAAGGCGGAAAACGTGATTCA
GTCAATGTAGCAGGTTTTGCGAAAGGTTATTTGGAGTCTTATTTAGCTGTTCGTCAGAGACGTTACAAGGCTGAAAAACA
GGATCTTGCTTTCTTTTTAACAGAATACCGTGGCGTTCCAAATCGAATGGATGCTTCTAGTATAGAAAAGATGGTTGGCA
AGTACTCTGAGGATTTTAAAATTCGTGTGACTCCTCACAAATTGCGTCATACGCTAGCGACAAGACTATATGATGCTACT
AAATCTCAGGTGTTAGTTAGTCATCAATTAGGCCATTCCTCTACTCAAGTCACGGATCTTTATACCCATATTGTCAATGA
TGAGCAAAAAAATGCTTTAGATAACCTTTAA

Domains

Predicted by InterProScan.

Phage integrase family (Phage_integrase)

(177-344)

Phage integrase, N-terminal SAM-like domain (Phage_int_SAM_4)

(33-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48TG2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  xerS Streptococcus pneumoniae R6

80.618

100

0.806

Multiple sequence alignment