Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NG812_RS02320 Genome accession   NZ_CP099987
Coordinates   468145..468840 (+) Length   231 a.a.
NCBI ID   WP_004259096.1    Uniprot ID   -
Organism   Lactococcus garvieae strain FUA009     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 463145..473840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NG812_RS02295 (NG812_02285) - 463378..464079 (+) 702 WP_004259114.1 DeoR/GlpR family DNA-binding transcription regulator -
  NG812_RS02300 (NG812_02290) pfkB 464076..465002 (+) 927 WP_165705969.1 1-phosphofructokinase -
  NG812_RS02305 (NG812_02295) - 465017..466921 (+) 1905 WP_014024348.1 fructose-specific PTS transporter subunit EIIC -
  NG812_RS02310 (NG812_02300) - 467033..467275 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  NG812_RS02315 (NG812_02305) - 467492..468043 (+) 552 WP_165705968.1 DUF177 domain-containing protein -
  NG812_RS02320 (NG812_02310) covR 468145..468840 (+) 696 WP_004259096.1 response regulator transcription factor Regulator
  NG812_RS02325 (NG812_02315) covS 468929..470419 (+) 1491 WP_014024351.1 HAMP domain-containing histidine kinase Regulator
  NG812_RS02330 (NG812_02320) - 470816..472387 (+) 1572 WP_165705967.1 ABC transporter permease subunit -
  NG812_RS02335 (NG812_02325) - 472388..473125 (+) 738 WP_141921008.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26979.74 Da        Isoelectric Point: 5.4730

>NTDB_id=703192 NG812_RS02320 WP_004259096.1 468145..468840(+) (covR) [Lactococcus garvieae strain FUA009]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQGNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=703192 NG812_RS02320 WP_004259096.1 468145..468840(+) (covR) [Lactococcus garvieae strain FUA009]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATACCAAACTGCGGTTCAAGGCAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TTGACTTAATGCTCCCAGAGCTTGATGGCTTTGAGGTTGCACGACGCTTACGCCGTGAGAAAGATACACATATTATTATG
ATGACTGCACGTGATTCGACAATGGACCGTGTAGCAGGTCTTGATATTGGCGCAGATGACTATATTACAAAACCATTTGC
TATTGAAGAATTGTTAGCGCGTGTCCGCTCACTCTTCCGTCGTGAAGATCATATCCACACGATTGAAAAGTCCGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAGACCAACCGTACTGTACACCGTGGAAAAAAAGTTATTGACCTTACACGTCGT
GAGTACGATTTGCTTTTGACACTGATGCAAAATGTAGGTGATGTCGTAACACGTGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTGGACGTTTATATCCGTTATCTGCGTAACAAAATTGACGTGGAGGGCCGTG
AAAGCTACATCCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

87.773

99.134

0.87
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424