Detailed information NTG0703193

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: NG812_RS02325
• Genome accession: NZ_CP099987
• Coordinates: 468929..470419 (+)
• Length: 496 a.a.
• NCBI ID: WP_014024351.1
• Uniprot ID: A0AA46TWW1
• Organism: Lactococcus garvieae strain FUA009
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 463929..475419

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NG812_RS02300 (NG812_02290)	pfkB	464076..465002 (+)	927	WP_165705969.1	1-phosphofructokinase	-
NG812_RS02305 (NG812_02295)	-	465017..466921 (+)	1905	WP_014024348.1	fructose-specific PTS transporter subunit EIIC	-
NG812_RS02310 (NG812_02300)	-	467033..467275 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
NG812_RS02315 (NG812_02305)	-	467492..468043 (+)	552	WP_165705968.1	DUF177 domain-containing protein	-
NG812_RS02320 (NG812_02310)	covR	468145..468840 (+)	696	WP_004259096.1	response regulator transcription factor	Regulator
NG812_RS02325 (NG812_02315)	covS	468929..470419 (+)	1491	WP_014024351.1	HAMP domain-containing histidine kinase	Regulator
NG812_RS02330 (NG812_02320)	-	470816..472387 (+)	1572	WP_165705967.1	ABC transporter permease subunit	-
NG812_RS02335 (NG812_02325)	-	472388..473125 (+)	738	WP_141921008.1	amino acid ABC transporter ATP-binding protein	-
NG812_RS02340 (NG812_02330)	murD	473264..474625 (+)	1362	WP_393187210.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56753.73 Da
• Isoelectric Point: 5.1966

>NTDB_id=703193 NG812_RS02325 WP_014024351.1 468929..470419(+) (covS) [Lactococcus garvieae strain FUA009]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=703193 NG812_RS02325 WP_014024351.1 468929..470419(+) (covS) [Lactococcus garvieae strain FUA009]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTCCGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTATCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCGC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCGGTTTATTCTAATAAAACAGGTAAGCTAATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCTTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGATACATCAAGCCTCTAGAACGGTTGCACGATGCGATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCTGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACGATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATTGATTTTCAAGATGAAGACCTTATCTG
TGATCCAACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATTCATGCTGATTTAAGCTTAACTGTTGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTATGATGGGGATGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• ArlS sensor domain (ArlS_N) (52-190)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• HAMP domain (HAMP) (214-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.936	100	0.56