Detailed information NTG0070225

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: KUN2590_RS00335
• Genome accession: NZ_AP023387
• Coordinates: 54375..55373 (+)
• Length: 332 a.a.
• NCBI ID: WP_011054100.1
• Uniprot ID: P0DF51
• Organism: Streptococcus pyogenes strain NIH34
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 49375..60373

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KUN2590_RS00320 (SPNIH34_00290)	-	50112..51452 (+)	1341	WP_002986685.1	hypothetical protein	-
KUN2590_RS00325 (SPNIH34_00300)	purB	51821..53113 (+)	1293	WP_011054098.1	adenylosuccinate lyase	-
KUN2590_RS00330 (SPNIH34_00310)	comR	53244..54155 (+)	912	WP_011054099.1	helix-turn-helix domain-containing protein	Regulator
KUN2590_RS09700	comS	54246..54344 (+)	99	WP_020833188.1	quorum-sensing system DWW-type pheromone	Regulator
KUN2590_RS00335 (SPNIH34_00320)	ruvB	54375..55373 (+)	999	WP_011054100.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
KUN2590_RS00340 (SPNIH34_00330)	-	55511..55948 (+)	438	WP_002994668.1	low molecular weight protein-tyrosine-phosphatase	-
KUN2590_RS00345 (SPNIH34_00340)	-	55971..56372 (+)	402	WP_011017240.1	MORN repeat-containing protein	-
KUN2590_RS00350 (SPNIH34_00350)	-	56369..58144 (+)	1776	WP_011054101.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37566.10 Da
• Isoelectric Point: 5.1632

>NTDB_id=70225 KUN2590_RS00335 WP_011054100.1 54375..55373(+) (ruvB) [Streptococcus pyogenes strain NIH34]
MARILDNDVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=70225 KUN2590_RS00335 WP_011054100.1 54375..55373(+) (ruvB) [Streptococcus pyogenes strain NIH34]
ATGGCTAGAATTTTAGACAATGATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGATTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGGCCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: P0DF51

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473