Detailed information NTG0702122

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: NIZ23_RS14770
• Genome accession: NZ_CP099874
• Coordinates: 2991319..2991948 (-)
• Length: 209 a.a.
• NCBI ID: WP_000839162.1
• Uniprot ID: A0A2T3RS91
• Organism: Escherichia albertii strain 251_2_EW_B
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	2977410..2991748	2991319..2991948	flank	-429

Gene organization within MGE regions

Location: 2977410..2991948

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NIZ23_RS14700 (NIZ23_14695)	-	2977473..2979953 (+)	2481	WP_149506592.1	exonuclease	-
NIZ23_RS14705 (NIZ23_14700)	-	2980020..2980271 (+)	252	WP_024237931.1	DUF4224 domain-containing protein	-
NIZ23_RS14710 (NIZ23_14705)	-	2980240..2981259 (+)	1020	WP_024227504.1	tyrosine-type recombinase/integrase	-
NIZ23_RS14715 (NIZ23_14710)	yccA	2981668..2982327 (+)	660	WP_000375136.1	FtsH protease modulator YccA	-
NIZ23_RS14720 (NIZ23_14715)	tusE	2982419..2982748 (+)	330	WP_024164819.1	sulfurtransferase TusE	-
NIZ23_RS14725 (NIZ23_14720)	yccX	2982745..2983023 (-)	279	WP_000048219.1	acylphosphatase	-
NIZ23_RS14730 (NIZ23_14725)	rlmI	2983117..2984307 (+)	1191	WP_059215636.1	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	-
NIZ23_RS14735 (NIZ23_14730)	hspQ	2984365..2984682 (+)	318	WP_001295356.1	heat shock protein HspQ	-
NIZ23_RS14740 (NIZ23_14735)	-	2984727..2985140 (-)	414	WP_002462360.1	CoA-binding protein	-
NIZ23_RS14745 (NIZ23_14740)	-	2985313..2985975 (+)	663	WP_000847777.1	DUF2057 family protein	-
NIZ23_RS14750 (NIZ23_14745)	mgsA	2986071..2986529 (+)	459	WP_000424182.1	methylglyoxal synthase	-
NIZ23_RS14755 (NIZ23_14750)	helD	2986561..2988615 (-)	2055	WP_059215651.1	DNA helicase IV	-
NIZ23_RS14760 (NIZ23_14755)	-	2988738..2989184 (+)	447	WP_001261228.1	YccF domain-containing protein	-
NIZ23_RS14765 (NIZ23_14760)	yccS	2989194..2991359 (+)	2166	WP_072244615.1	YccS family putative transporter	-
NIZ23_RS14770 (NIZ23_14765)	sxy/tfoX	2991319..2991948 (-)	630	WP_000839162.1	TfoX/Sxy family DNA transformation protein	Regulator

Sequence

Protein

• Length: 209 a.a.
• Molecular weight: 24291.21 Da
• Isoelectric Point: 9.0264

>NTDB_id=702122 NIZ23_RS14770 WP_000839162.1 2991319..2991948(-) (sxy/tfoX) [Escherichia albertii strain 251_2_EW_B]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVNDTVFAMVADGELYLRACEQSVQYCVKHPPVWLTYKKCGRPVTLN
YYRVDESLWRNQQKLVRLSKYSLDAALKEKCTRNNLQRLKDLPNMSYHLEAILGEVGIKDVRTLRILGAKMCWLRLRQHN
SQVTEKILFMLEGAIIDIHEAALPVARRQELAEWAESIVPKPEFPTEPE

Nucleotide

• Length: 630 bp

>NTDB_id=702122 NIZ23_RS14770 WP_000839162.1 2991319..2991948(-) (sxy/tfoX) [Escherichia albertii strain 251_2_EW_B]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAGTCACAAGAATACCTTGCAACGTTAGGCACCATTGAATATCGATCGCT
GTTTGGCAGTTACAGTTTGACGGTTAACGATACGGTATTTGCGATGGTTGCTGATGGTGAGTTGTATCTACGGGCTTGTG
AACAAAGCGTACAGTACTGTGTAAAACATCCGCCAGTCTGGCTGACATATAAAAAGTGCGGCCGACCCGTGACTCTCAAT
TACTACCGGGTTGATGAAAGTCTATGGCGTAACCAACAGAAATTAGTTCGCTTGTCGAAATATTCCCTGGATGCTGCGCT
GAAAGAGAAATGTACGCGCAACAATCTCCAGCGACTGAAAGATTTGCCGAATATGTCTTATCACCTGGAGGCGATTCTCG
GTGAAGTGGGGATCAAGGATGTGCGGACTTTACGGATCCTTGGCGCAAAAATGTGCTGGTTGCGACTACGTCAGCATAAT
AGCCAGGTGACGGAGAAGATCTTATTCATGCTTGAAGGCGCAATTATTGATATTCATGAAGCAGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCTGAATGGGCTGAATCTATTGTGCCGAAACCGGAGTTTCCGACGGAACCTGAGTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (117-194)

• TfoX N-terminal domain (TfoX_N) (14-106)

3D structure

• AlphaFold DB: A0A2T3RS91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Escherichia coli BW25113 strain K-12	90.431	100	0.904