Detailed information NTG0070088

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: JMH23_RS21220
• Genome accession: NZ_AP023286
• Coordinates: 4452580..4453605 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain 2018-18.25PC
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4447580..4458605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMH23_RS21200 (VEGS15_41420)	metJ	4448641..4448958 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
JMH23_RS21205 (VEGS15_41430)	yiiX	4449142..4449750 (+)	609	WP_000797353.1	YiiX family permuted papain-like enzyme	-
JMH23_RS21210 (VEGS15_41440)	rpmE	4449811..4450023 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
JMH23_RS21215 (VEGS15_41450)	priA	4450226..4452424 (+)	2199	WP_001301269.1	primosomal protein N'	Machinery gene
JMH23_RS21220 (VEGS15_41460)	cytR	4452580..4453605 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
JMH23_RS21225 (VEGS15_41470)	ftsN	4453697..4454656 (+)	960	WP_000068828.1	cell division protein FtsN	-
JMH23_RS21230 (VEGS15_41480)	hslV	4454749..4455279 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
JMH23_RS21235 (VEGS15_41490)	hslU	4455289..4456620 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
JMH23_RS21240 (VEGS15_41500)	menA	4456687..4457613 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
JMH23_RS21245 (VEGS15_41510)	rraA	4457706..4458191 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
JMH23_RS21250 (VEGS15_41520)	zapB	4458276..4458521 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=70088 JMH23_RS21220 WP_000644904.1 4452580..4453605(+) (cytR) [Escherichia coli strain 2018-18.25PC]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=70088 JMH23_RS21220 WP_000644904.1 4452580..4453605(+) (cytR) [Escherichia coli strain 2018-18.25PC]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628