Detailed information    

insolico Bioinformatically predicted

Overview


Name   dprA   Type   Machinery gene
Locus tag   SA58113_RS06230 Genome accession   NZ_AP018562
Coordinates   1260144..1261016 (+) Length   290 a.a.
NCBI ID   WP_031786943.1    Uniprot ID   -
Organism   Staphylococcus argenteus strain 58113     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1223548..1305918 1260144..1261016 within 0


Gene organization within MGE regions


Location: 1223548..1305918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA58113_RS06065 (SA58113_1171) - 1223703..1223906 (-) 204 WP_001198027.1 TM2 domain-containing protein -
  SA58113_RS06070 (SA58113_1172) - 1224207..1224695 (+) 489 WP_031787794.1 peptide deformylase -
  SA58113_RS06075 (SA58113_1173) fmt 1224688..1225623 (+) 936 WP_000161302.1 methionyl-tRNA formyltransferase -
  SA58113_RS06080 (SA58113_1174) rsmB 1225620..1226927 (+) 1308 WP_031787795.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SA58113_RS06085 (SA58113_1175) rlmN 1226930..1228024 (+) 1095 WP_000626892.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  SA58113_RS06090 (SA58113_1176) - 1228031..1228774 (+) 744 WP_000888496.1 protein-serine/threonine phosphatase Stp1 -
  SA58113_RS06095 (SA58113_1177) pknB 1228771..1230765 (+) 1995 WP_031787796.1 serine/threonine protein kinase Stk1 -
  SA58113_RS06100 (SA58113_1178) rsgA 1231032..1231907 (+) 876 WP_000847920.1 ribosome small subunit-dependent GTPase A -
  SA58113_RS06105 (SA58113_1179) rpe 1231908..1232552 (+) 645 WP_031787797.1 ribulose-phosphate 3-epimerase -
  SA58113_RS06110 (SA58113_1180) - 1232559..1233203 (+) 645 WP_031787798.1 thiamine diphosphokinase -
  SA58113_RS06115 (SA58113_1181) rpmB 1233453..1233641 (-) 189 WP_000517908.1 50S ribosomal protein L28 -
  SA58113_RS06120 (SA58113_1182) - 1234085..1234459 (+) 375 WP_031787799.1 Asp23/Gls24 family envelope stress response protein -
  SA58113_RS06125 (SA58113_1183) fakA 1234474..1236120 (+) 1647 WP_031787800.1 fatty acid kinase catalytic subunit FakA -
  SA58113_RS06130 (SA58113_1184) recG 1236294..1238354 (+) 2061 WP_031787801.1 ATP-dependent DNA helicase RecG -
  SA58113_RS06135 (SA58113_1185) fapR 1238759..1239331 (+) 573 WP_072292002.1 transcription factor FapR -
  SA58113_RS06140 (SA58113_1186) plsX 1239336..1240322 (+) 987 WP_000239751.1 phosphate acyltransferase PlsX -
  SA58113_RS06145 (SA58113_1187) fabD 1240315..1241241 (+) 927 WP_031787802.1 ACP S-malonyltransferase -
  SA58113_RS06150 (SA58113_1188) fabG 1241234..1241968 (+) 735 WP_000167268.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  SA58113_RS06155 (SA58113_1189) - 1242438..1242671 (+) 234 WP_000426914.1 acyl carrier protein -
  SA58113_RS06160 (SA58113_1190) rnc 1242787..1243518 (+) 732 WP_000043235.1 ribonuclease III -
  SA58113_RS06165 (SA58113_1191) smc 1243650..1247219 (+) 3570 WP_031788253.1 chromosome segregation protein SMC -
  SA58113_RS06170 (SA58113_1192) ftsY 1247216..1248466 (+) 1251 WP_031788254.1 signal recognition particle-docking protein FtsY -
  SA58113_RS06175 (SA58113_1193) - 1248453..1248785 (+) 333 WP_000531321.1 putative DNA-binding protein -
  SA58113_RS06180 (SA58113_1194) ffh 1248810..1250177 (+) 1368 WP_000863483.1 signal recognition particle protein -
  SA58113_RS06185 (SA58113_1195) rpsP 1250506..1250781 (+) 276 WP_000268754.1 30S ribosomal protein S16 -
  SA58113_RS06190 (SA58113_1196) rimM 1250968..1251471 (+) 504 WP_001261978.1 ribosome maturation factor RimM -
  SA58113_RS06195 (SA58113_1197) trmD 1251471..1252208 (+) 738 WP_031786939.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  SA58113_RS06200 (SA58113_1198) rplS 1252311..1252661 (+) 351 WP_000181404.1 50S ribosomal protein L19 -
  SA58113_RS06205 (SA58113_1199) - 1252903..1255509 (-) 2607 WP_031786940.1 YfhO family protein -
  SA58113_RS06210 (SA58113_1200) ylqF 1255909..1256793 (+) 885 WP_031786941.1 ribosome biogenesis GTPase YlqF -
  SA58113_RS06215 (SA58113_1201) - 1256777..1257544 (+) 768 WP_031786942.1 ribonuclease HII -
  SA58113_RS06220 (SA58113_1202) sucC 1257653..1258819 (+) 1167 WP_001020805.1 ADP-forming succinate--CoA ligase subunit beta -
  SA58113_RS06225 (SA58113_1203) sucD 1258841..1259749 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  SA58113_RS06230 (SA58113_1204) dprA 1260144..1261016 (+) 873 WP_031786943.1 DNA-processing protein DprA Machinery gene
  SA58113_RS06235 (SA58113_1205) topA 1261190..1263265 (+) 2076 WP_072324151.1 type I DNA topoisomerase -
  SA58113_RS06240 (SA58113_1206) trmFO 1263421..1264728 (+) 1308 WP_000195261.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  SA58113_RS06245 (SA58113_1207) xerC 1265143..1266039 (+) 897 WP_031786945.1 tyrosine recombinase XerC -
  SA58113_RS06250 (SA58113_1208) hslV 1266036..1266581 (+) 546 WP_000072683.1 ATP-dependent protease subunit HslV -
  SA58113_RS06255 (SA58113_1209) hslU 1266646..1268049 (+) 1404 WP_000381629.1 ATP-dependent protease ATPase subunit HslU -
  SA58113_RS06260 (SA58113_1210) codY 1268074..1268847 (+) 774 WP_000055333.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  SA58113_RS06265 (SA58113_1211) rpsB 1269124..1269891 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  SA58113_RS06270 - 1269943..1270038 (+) 96 WP_225995268.1 hypothetical protein -
  SA58113_RS06275 (SA58113_1212) tsf 1270073..1270954 (+) 882 WP_031786946.1 translation elongation factor Ts -
  SA58113_RS06280 (SA58113_1213) pyrH 1271091..1271813 (+) 723 WP_000057330.1 UMP kinase -
  SA58113_RS06285 (SA58113_1214) frr 1271832..1272386 (+) 555 WP_001280034.1 ribosome recycling factor -
  SA58113_RS06290 (SA58113_1215) - 1272747..1273517 (+) 771 WP_000473698.1 isoprenyl transferase -
  SA58113_RS06295 (SA58113_1216) - 1273524..1274306 (+) 783 WP_000868415.1 phosphatidate cytidylyltransferase -
  SA58113_RS06300 (SA58113_1217) rseP 1274517..1275803 (+) 1287 WP_031786947.1 RIP metalloprotease RseP -
  SA58113_RS06305 (SA58113_1218) - 1275823..1277526 (+) 1704 WP_031786948.1 proline--tRNA ligase -
  SA58113_RS06310 (SA58113_1219) - 1277800..1282110 (+) 4311 WP_078097697.1 PolC-type DNA polymerase III -
  SA58113_RS06320 (SA58113_1220) rimP 1282386..1282853 (+) 468 WP_031786950.1 ribosome maturation factor RimP -
  SA58113_RS06325 (SA58113_1221) nusA 1282874..1284049 (+) 1176 WP_000097470.1 transcription termination factor NusA -
  SA58113_RS06330 (SA58113_1222) rnpM 1284070..1284354 (+) 285 WP_031786951.1 RNase P modulator RnpM -
  SA58113_RS06335 (SA58113_1223) - 1284351..1284668 (+) 318 WP_000021269.1 YlxQ family RNA-binding protein -
  SA58113_RS06340 (SA58113_1224) infB 1284673..1286799 (+) 2127 WP_000043647.1 translation initiation factor IF-2 -
  SA58113_RS06345 (SA58113_1225) rbfA 1287128..1287478 (+) 351 WP_000097321.1 30S ribosome-binding factor RbfA -
  SA58113_RS06350 (SA58113_1226) truB 1287650..1288567 (+) 918 WP_000282309.1 tRNA pseudouridine(55) synthase TruB -
  SA58113_RS06355 (SA58113_1227) ribF 1288582..1289553 (+) 972 WP_031786952.1 riboflavin biosynthesis protein RibF -
  SA58113_RS06360 (SA58113_1228) rpsO 1289668..1289937 (+) 270 WP_001018327.1 30S ribosomal protein S15 -
  SA58113_RS06365 (SA58113_1229) pnp 1290304..1292400 (+) 2097 WP_000076680.1 polyribonucleotide nucleotidyltransferase -
  SA58113_RS06375 (SA58113_1230) rnjB 1292643..1294316 (+) 1674 WP_000052592.1 ribonuclease J2 -
  SA58113_RS06380 (SA58113_1231) - 1294588..1296960 (+) 2373 WP_031786953.1 FtsK/SpoIIIE family DNA translocase -
  SA58113_RS06385 (SA58113_1232) - 1296964..1297677 (+) 714 WP_001293301.1 GntR family transcriptional regulator -
  SA58113_RS06390 (SA58113_1233) yfmF 1297708..1298973 (+) 1266 WP_031786954.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  SA58113_RS06395 (SA58113_1234) yfmH 1298973..1300259 (+) 1287 WP_031786955.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  SA58113_RS06400 (SA58113_1235) ymfI 1300259..1300963 (+) 705 WP_000646238.1 elongation factor P 5-aminopentanone reductase -
  SA58113_RS06405 (SA58113_1236) - 1301071..1301898 (+) 828 WP_031786956.1 DUF3388 domain-containing protein -
  SA58113_RS06410 (SA58113_1237) - 1301923..1302315 (+) 393 WP_000859442.1 helix-turn-helix domain-containing protein -
  SA58113_RS06415 (SA58113_1238) pgsA 1302347..1302925 (+) 579 WP_031786957.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  SA58113_RS06420 (SA58113_1239) - 1303167..1304318 (+) 1152 WP_031786958.1 CinA family nicotinamide mononucleotide deamidase-related protein -
  SA58113_RS06425 (SA58113_1240) recA 1304483..1305526 (+) 1044 WP_000368169.1 recombinase RecA Machinery gene
  SA58113_RS06430 - 1305708..1305853 (-) 146 Protein_1230 ISL3 family transposase -

Sequence


Protein


Download         Length: 290 a.a.        Molecular weight: 33128.01 Da        Isoelectric Point: 9.3910

>NTDB_id=70088 SA58113_RS06230 WP_031786943.1 1260144..1261016(+) (dprA) [Staphylococcus argenteus strain 58113]
MLNQILLKLIWSHFTTSQIHQLFNKFPNFLEVDELEQNYLLRKFVLNNSNENLSIKNEVYSRISFDEIMSNIQQSKLNFI
TCFDKGYPSYLKEIYDYPFVLFYKGSINILSSPKALAVVGSRVSSNYTTKALNHLFYSFQQSNLTIVSGLAQGADAMAHQ
TALKYNLPTIAVLAFGHQTHYPKSTRALRNKIEEKGLVISEYPPHTPIARYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDILEDYFI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=70088 SA58113_RS06230 WP_031786943.1 1260144..1261016(+) (dprA) [Staphylococcus argenteus strain 58113]
ATGTTAAATCAAATTCTACTTAAATTAATTTGGAGTCATTTTACAACTTCGCAAATTCACCAGCTATTTAATAAATTTCC
AAACTTTTTAGAAGTAGATGAACTTGAACAAAATTATCTACTACGCAAATTTGTTTTAAATAATTCAAATGAGAATCTTT
CGATTAAAAATGAGGTTTATAGTCGAATTTCTTTTGATGAAATAATGTCAAATATCCAACAAAGCAAATTGAACTTTATA
ACTTGTTTTGATAAAGGGTATCCTAGTTACTTAAAAGAAATTTACGACTATCCATTTGTTTTATTTTATAAAGGGAGTAT
TAATATCCTCAGTTCTCCTAAAGCATTAGCTGTAGTTGGTTCGAGAGTTTCAAGCAATTATACAACAAAAGCATTGAACC
ATCTTTTCTATTCGTTCCAACAATCAAATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ACAGCATTAAAATACAATCTCCCTACAATAGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACACGAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTGATATCCGAATATCCACCGCATACACCAATTGCTAGATATAGATTTC
CAGAACGAAATAGAATTATCAGTGGGTTGTCAAAAGGGGTTCTAATAACAGAAGCTAAAGAACAAAGTGGTAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAACAGAAATGTTTATGTTTTACCAGGATCAATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGAGCTAAGGTAGTTTTAAACGCTAATGATATATTAGAAGATTACTTTATTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

67.123

100

0.676

  dprA Staphylococcus aureus N315

67.123

100

0.676

  dprA/cilB/dalA Streptococcus pneumoniae Rx1

37.722

96.897

0.366

  dprA/cilB/dalA Streptococcus pneumoniae D39

37.722

96.897

0.366

  dprA/cilB/dalA Streptococcus pneumoniae R6

37.722

96.897

0.366

  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

37.722

96.897

0.366

  dprA/cilB/dalA Streptococcus mitis SK321

37.722

96.897

0.366

  dprA/cilB/dalA Streptococcus mitis NCTC 12261

37.367

96.897

0.362


Multiple sequence alignment