Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   SA27298_RS09585 Genome accession   NZ_AP018548
Coordinates   1950847..1952172 (-) Length   441 a.a.
NCBI ID   WP_211209167.1    Uniprot ID   -
Organism   Streptococcus anginosus strain CCUG 27928     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1945847..1957172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA27298_RS09565 (SA27298_1946) - 1947174..1949750 (+) 2577 WP_018543657.1 YfhO family protein -
  SA27298_RS09580 (SA27298_1949) comE 1950098..1950847 (-) 750 WP_018543656.1 competence system response regulator transcription factor ComE Regulator
  SA27298_RS09585 (SA27298_1950) comD/comD2 1950847..1952172 (-) 1326 WP_211209167.1 GHKL domain-containing protein Regulator
  SA27298_RS09590 (SA27298_1951) - 1952190..1952336 (-) 147 WP_003029519.1 bacteriocin -
  SA27298_RS09600 (SA27298_1953) rlmH 1952618..1953097 (-) 480 WP_003032032.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SA27298_RS09605 (SA27298_1954) htrA 1953291..1954481 (+) 1191 WP_003032033.1 trypsin-like peptidase domain-containing protein Regulator
  SA27298_RS09610 (SA27298_1955) spo0J 1954536..1955303 (+) 768 WP_003032028.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 52015.77 Da        Isoelectric Point: 8.4767

>NTDB_id=70013 SA27298_RS09585 WP_211209167.1 1950847..1952172(-) (comD/comD2) [Streptococcus anginosus strain CCUG 27928]
MVKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFSTDFTTLIHYSIRYMMFFIQPLFFYLYFFKVKKV
KKHLSVFLALFLSLAVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKIDFKENIVQ
LNFYLLFIHLLLNVSHWLSNMKNLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLY
NEIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKTRDYNIEL
TFEVKDFVNPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGE
GRGLGLSNIKEIINNYEGIILDTKIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=70013 SA27298_RS09585 WP_211209167.1 1950847..1952172(-) (comD/comD2) [Streptococcus anginosus strain CCUG 27928]
ATTGTGAAAATAGAATTTATACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGCTATAAGAAAAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTCAACTGATTTCACTACTTTAA
TACATTATTCCATTAGATATATGATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTT
AAAAAACACCTTTCTGTATTTTTAGCATTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTAT
TTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATATTGGGGATTGTTCTATATTTTTATTAATATTATTTCTTTAGTTT
TCATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGATAGATTTTAAAGAAAATATTGTACAA
TTAAATTTTTATCTATTATTTATTCATCTTTTATTAAATGTATCGCATTGGCTTAGTAACATGAAAAATTTAAATAGTTT
TTCTAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAATTTTGTTCTACTTACAATCTATTCGCGAAAAGTATG
AAAAAGAAGAACAAATTAAACAAAAAGAACGAGAACAATTACAATTACAAAAATATACAGATGAAATTGTGAGTCTGTAT
AATGAAATTCGAGGCTTTCGCCATGATTATGGAGGAATGTTGGCAAGCTTCCAATCGGCCATTCATACAGGTGATATAAA
AGAAGTAGAGCGAATTTATCAGGAAGTACTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACGTATTTTGATT
TAAATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACACAAACCTTATTTAAGACGCGTGACTATAATATAGAATTA
ACATTTGAAGTAAAAGATTTTGTCAACCCCTTGCCGATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTCCTTTTAAA
TAATGCAATAGAGGGAGCGGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTAGTAGATCTGGATACAGAAACAATCT
TAGTTATTCAAAATTCACGTAAGAAACGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAA
GGACGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGA
TGAATATTTTACACAAGTAATGAGAGTGCGGAAAGAAGGGTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.299

100

0.544
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

58.901

86.621

0.51
  comD Streptococcus mitis SK321

46.939

88.889

0.417
  comD Streptococcus mitis NCTC 12261

48.404

85.261

0.413
  comD/comD2 Streptococcus pneumoniae TIGR4

47.872

85.261

0.408
  comD/comD1 Streptococcus pneumoniae Rx1

47.34

85.261

0.404
  comD/comD1 Streptococcus pneumoniae D39

47.34

85.261

0.404
  comD/comD1 Streptococcus pneumoniae R6

47.34

85.261

0.404

Multiple sequence alignment