Detailed information NTG0069964

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: SA27298_RS02085
• Genome accession: NZ_AP018548
• Coordinates: 410010..410684 (-)
• Length: 224 a.a.
• NCBI ID: WP_018543646.1
• Uniprot ID: A0A448AIB9
• Organism: Streptococcus anginosus strain CCUG 27928
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 405010..415684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA27298_RS02055 (SA27298_0420)	rsmD	405614..406162 (+)	549	WP_025271932.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SA27298_RS02060 (SA27298_0421)	coaD	406152..406649 (+)	498	WP_003032432.1	pantetheine-phosphate adenylyltransferase	-
SA27298_RS02065 (SA27298_0422)	sepM	406630..407685 (+)	1056	WP_003032358.1	SepM family pheromone-processing serine protease	Regulator
SA27298_RS02070 (SA27298_0423)	-	407825..408388 (+)	564	WP_026248195.1	YutD family protein	-
SA27298_RS02075 (SA27298_0424)	rlmN	408422..409504 (+)	1083	WP_018543645.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SA27298_RS02080 (SA27298_0425)	-	409497..410015 (+)	519	WP_003032357.1	VanZ family protein	-
SA27298_RS02085 (SA27298_0426)	cclA/cilC	410010..410684 (-)	675	WP_018543646.1	A24 family peptidase	Machinery gene
SA27298_RS02090 (SA27298_0427)	-	410838..411365 (+)	528	WP_003032411.1	Dps family protein	-
SA27298_RS02095 (SA27298_0428)	-	411639..411863 (+)	225	WP_003025724.1	YqgQ family protein	-
SA27298_RS02100 (SA27298_0429)	-	411857..412237 (+)	381	WP_018543647.1	rhodanese-like domain-containing protein	-
SA27298_RS02105 (SA27298_0430)	-	412258..412983 (-)	726	WP_003032391.1	pseudouridine synthase	-
SA27298_RS02110 (SA27298_0431)	typA	413161..415002 (+)	1842	WP_003032385.1	translational GTPase TypA	-
SA27298_RS02115 (SA27298_0432)	-	415067..415351 (+)	285	WP_003025714.1	DUF3165 family protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25185.47 Da
• Isoelectric Point: 8.3081

>NTDB_id=69964 SA27298_RS02085 WP_018543646.1 410010..410684(-) (cclA/cilC) [Streptococcus anginosus strain CCUG 27928]
MIHFYFFLVGSIVASFLGLVVDRFPEQSILVPSSHCNACGQKLAPRDLVPVLSQLINRLRCRFCNSKIPIRYILLELTGG
CLFLATSLGYLNINRLVLLAMGMTLSLYDQREQEYPLLIWLIFHIFLLFLTSFNLLMVAFLALGILAHFVDLRIGAGDFL
FLASCSTIFHLTEVLLIIQIASIIGLLLFGLKSKKDRLAFVPCLFCGSSILIMIQFIVLHQNAL

Nucleotide

• Length: 675 bp

>NTDB_id=69964 SA27298_RS02085 WP_018543646.1 410010..410684(-) (cclA/cilC) [Streptococcus anginosus strain CCUG 27928]
ATGATTCATTTTTATTTTTTCTTGGTTGGAAGCATTGTAGCTTCCTTTTTAGGGCTGGTCGTTGATCGTTTCCCTGAACA
GTCTATTCTCGTTCCTTCCAGTCATTGTAATGCTTGTGGACAGAAATTAGCACCTCGTGATTTAGTCCCTGTCCTTTCTC
AGCTTATCAATCGACTGCGTTGTCGGTTTTGCAACTCAAAAATTCCCATCCGTTACATCCTTCTAGAACTAACTGGTGGC
TGTCTCTTTCTTGCAACATCTTTAGGTTATCTAAACATCAACCGGCTCGTTTTGCTTGCAATGGGAATGACCTTATCCCT
TTATGATCAAAGAGAACAAGAATATCCTCTCCTCATCTGGTTAATCTTTCATATTTTTCTCCTTTTTTTGACAAGCTTCA
ATCTTTTAATGGTTGCTTTTTTAGCACTTGGGATTTTGGCTCACTTCGTTGATTTACGTATCGGTGCAGGAGACTTTCTT
TTTCTGGCATCTTGCTCAACTATTTTTCATCTGACTGAAGTTCTTCTCATTATTCAAATTGCTAGTATCATTGGTCTGCT
CCTTTTTGGTTTAAAATCAAAAAAAGACAGGTTAGCCTTTGTTCCCTGTCTTTTCTGTGGTAGCAGCATCCTGATAATGA
TACAATTTATCGTTCTTCACCAAAATGCCTTATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-87)

3D structure

• AlphaFold DB: A0A448AIB9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis SK321	57.075	94.643	0.54
cclA/cilC	Streptococcus mitis NCTC 12261	56.604	94.643	0.536
cclA/cilC	Streptococcus pneumoniae TIGR4	56.132	94.643	0.531
cclA/cilC	Streptococcus pneumoniae Rx1	55.66	94.643	0.527
cclA/cilC	Streptococcus pneumoniae D39	55.66	94.643	0.527
cclA/cilC	Streptococcus pneumoniae R6	55.66	94.643	0.527