Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EP162_RS01510 Genome accession   NZ_AP018524
Coordinates   345800..347107 (-) Length   435 a.a.
NCBI ID   WP_048590085.1    Uniprot ID   -
Organism   Melissococcus plutonius strain DAT585     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 340800..352107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP162_RS01490 (DAT585_0299) mreC 341343..342200 (+) 858 WP_013773244.1 rod shape-determining protein MreC -
  EP162_RS01495 (DAT585_0300) mreD 342203..342712 (+) 510 WP_013773245.1 rod shape-determining protein MreD -
  EP162_RS01500 (DAT585_0301) - 343016..344602 (+) 1587 WP_048590084.1 CHAP domain-containing protein -
  EP162_RS01505 (DAT585_0302) - 344851..345420 (+) 570 WP_013773247.1 TetR/AcrR family transcriptional regulator -
  EP162_RS01510 (DAT585_0303) htrA 345800..347107 (-) 1308 WP_048590085.1 S1C family serine protease Regulator
  EP162_RS01515 (DAT585_0304) rlmH 347506..347985 (+) 480 WP_013773250.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EP162_RS01520 (DAT585_0305) - 348869..349519 (+) 651 WP_172956752.1 hypothetical protein -
  EP162_RS09180 - 349756..349929 (+) 174 WP_013773252.1 hypothetical protein -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 45783.42 Da        Isoelectric Point: 6.7497

>NTDB_id=69836 EP162_RS01510 WP_048590085.1 345800..347107(-) (htrA) [Melissococcus plutonius strain DAT585]
MERKNVTPISNKKNSFFKKFGIGLLGGVVGGVLIIGGTYAAVGMNVLSSPSATNTNNSLTPAKSTKVSNINYNVNSDVTK
AVNKTQDSVVSVINLQQKKSSSDLDGLDGLFGNDDNNNKKNKDNSSGGLEAASEGSGVIYKKDGNTAYVVTNNHVVDQSN
GLEVILHDGTKVKGKLVGKDAYTDLAVIKIAAQKVDQIATFGDSSKLKVGEPAIAIGSPLGSEYANSVTQGIISSVNRNI
TNANESGETVNINAIQTDAAINPGNSGGPLINIEGQVIGINSIKILQANSQVNVEGMGFAIPSNDVVSIINQLEAKGKVT
RPALGITMEDLSNISSQQQEEILKLPSSIKSGIVVLSVQAATPADKSGLKKYDVITKVDGENINTITDLQSALYKKNVGD
SMEVTYYRESKEHTASVDLTIDKSALKQPSIQENR

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=69836 EP162_RS01510 WP_048590085.1 345800..347107(-) (htrA) [Melissococcus plutonius strain DAT585]
ATGGAAAGAAAAAATGTAACACCTATTTCTAATAAAAAAAATTCATTTTTTAAAAAATTTGGCATTGGTTTACTCGGTGG
TGTAGTAGGCGGTGTTTTAATCATTGGTGGTACTTATGCTGCAGTTGGTATGAATGTTTTATCCTCTCCATCTGCCACAA
ATACAAATAATTCTTTAACGCCAGCTAAAAGCACTAAAGTAAGTAATATTAATTATAATGTAAATAGTGATGTAACAAAA
GCTGTTAATAAAACTCAAGATTCAGTCGTTTCTGTGATCAATCTACAACAAAAAAAATCTTCTTCTGATTTAGATGGCTT
AGATGGTCTCTTTGGAAATGATGATAATAACAATAAAAAAAATAAGGATAATAGTTCAGGTGGCTTAGAAGCTGCTAGTG
AAGGTAGTGGCGTTATTTATAAAAAAGATGGCAATACTGCCTATGTCGTAACCAATAATCATGTAGTTGATCAATCAAAC
GGATTGGAAGTTATTTTACATGATGGAACAAAAGTTAAAGGGAAATTAGTTGGAAAAGATGCTTATACCGATTTAGCAGT
TATTAAAATTGCTGCCCAAAAAGTAGATCAAATTGCTACATTCGGAGACTCTAGTAAACTAAAAGTTGGCGAACCCGCCA
TTGCAATTGGTTCTCCATTAGGTTCAGAGTATGCCAACTCGGTTACACAAGGAATTATTTCTTCAGTAAATCGTAATATT
ACAAATGCAAATGAATCGGGAGAAACTGTCAATATTAATGCAATACAGACAGATGCAGCAATTAATCCCGGAAATTCTGG
TGGTCCACTAATTAATATTGAAGGACAAGTTATTGGGATTAACTCCATTAAAATCCTTCAAGCTAATAGTCAAGTTAATG
TTGAAGGTATGGGATTCGCTATTCCTAGTAATGATGTTGTATCTATTATCAACCAACTAGAAGCCAAAGGAAAAGTAACA
CGCCCAGCATTAGGAATCACAATGGAAGACCTATCAAATATTTCTTCACAACAACAAGAAGAAATATTGAAATTACCTTC
TTCTATAAAATCTGGTATTGTTGTTCTTTCTGTTCAGGCAGCAACACCAGCCGATAAATCAGGTTTAAAAAAATATGATG
TCATTACAAAGGTTGATGGAGAAAATATCAATACAATCACAGATCTACAAAGTGCACTTTATAAAAAAAATGTTGGTGAC
TCAATGGAGGTAACCTATTATCGTGAATCAAAAGAGCATACTGCATCTGTTGATTTAACAATTGACAAATCAGCATTAAA
ACAACCTTCTATACAAGAAAATCGTTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(239-420)

PDZ domain (PDZ_2)

(322-419)

Trypsin-like peptidase domain (Trypsin_2)

(135-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

53.253

95.402

0.508
  htrA Streptococcus gordonii str. Challis substr. CH1

52.415

95.172

0.499
  htrA Streptococcus mitis NCTC 12261

51.095

94.483

0.483
  htrA Streptococcus pneumoniae TIGR4

54.598

80

0.437
  htrA Streptococcus pneumoniae Rx1

54.598

80

0.437
  htrA Streptococcus pneumoniae D39

54.598

80

0.437
  htrA Streptococcus pneumoniae R6

54.598

80

0.437

Multiple sequence alignment