Detailed information NTG0697933

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: M0D19_RS00415
• Genome accession: NZ_CP098784
• Coordinates: 71459..73606 (-)
• Length: 715 a.a.
• NCBI ID: WP_096638837.1
• Uniprot ID: -
• Organism: Leuconostoc mesenteroides strain WiKim0121
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 66459..78606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M0D19_RS00395 (M0D19_00395)	-	67653..68240 (+)	588	WP_014324154.1	helix-turn-helix domain-containing protein	-
M0D19_RS00400 (M0D19_00400)	-	68298..69035 (+)	738	WP_002815471.1	SDR family NAD(P)-dependent oxidoreductase	-
M0D19_RS00405 (M0D19_00405)	-	69151..69276 (+)	126	WP_011679061.1	putative metal homeostasis protein	-
M0D19_RS00410 (M0D19_00410)	-	70092..71441 (-)	1350	WP_135400361.1	bacteriocin secretion accessory protein	-
M0D19_RS00415 (M0D19_00415)	comA	71459..73606 (-)	2148	WP_096638837.1	peptide cleavage/export ABC transporter	Regulator
M0D19_RS00420 (M0D19_00420)	-	74295..74495 (+)	201	WP_252169338.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
M0D19_RS00425 (M0D19_00425)	-	74488..74652 (+)	165	WP_096638839.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
M0D19_RS00430 (M0D19_00430)	-	75221..75364 (+)	144	Protein_65	class IIb bacteriocin, lactobin A/cerein 7B family	-
M0D19_RS00435 (M0D19_00435)	-	75394..75555 (+)	162	WP_080732741.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
M0D19_RS00440 (M0D19_00440)	-	76177..76356 (+)	180	WP_135400366.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
M0D19_RS00445 (M0D19_00445)	-	76370..76543 (+)	174	WP_072612884.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
M0D19_RS00450 (M0D19_00450)	-	76549..76761 (+)	213	WP_011679067.1	hypothetical protein	-
M0D19_RS00455 (M0D19_00455)	-	77033..77758 (-)	726	WP_011679068.1	response regulator transcription factor	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80350.34 Da
• Isoelectric Point: 9.2370

>NTDB_id=697933 M0D19_RS00415 WP_096638837.1 71459..73606(-) (comA) [Leuconostoc mesenteroides strain WiKim0121]
MRKFHYISQLEEKDCGVAALAMILKRHGSDVSLANIRERCQTSLSGTTALGLVKAAESFNMDVRPIQADLTLFNMKDLPL
PFIAHVEKKGQYLHYYVVYGFTKNKVIIADPDPTVAKTAMTLQEFSKEWTGVALFMSPSPRYKPFKENKNSILSFLPIIS
RQKGLIANIVVASLLVTLISIAGSYYMQLVIDAYIPSAMSNTLTVVSLGLIATYVLQQLLSFARTYLLTIMGQRLSIEVI
LSYIRHLFELPVNFFATRRTGEIVTRFNDANTIIDAMANTILSLFLDLGITIIVGSVLAIQNTKLFLLSLISFPIYFLIV
YCFMKPFERLNQEQMASNATLSSSIIEDINGIETIKSLTSEKTSYQKIDREFVDYLKKSFAHQKSEAIQNSIKQATQLII
NVLVLWLGAKLVISNQISVGQLVTYNALLGYFTEPFQNIINLQAKLQTATVANRRLNEVYLVKSEFKKSESQELHHNNPH
NIIVDDVSYQYGYQKNILHHFSIKIPFGEKIALVGVSGSGKSTLAKLLVHFISPSAGNIFIGEQNIKHVQRQNLRQHILY
LPQNPYIFTGSILDNLTLGARENTTQEDILHAVELADIKDDIENMPQSYQTEISEEGGMSGGQKQRIALARALLSNSQIL
ILDESTSNLDVATEKKIIDNLLSLKNKTIIFIAHRLTIAEKVQRVILLEKGIISEDGSHAELIHKKSKYYHLVKH

Nucleotide

• Length: 2148 bp

>NTDB_id=697933 M0D19_RS00415 WP_096638837.1 71459..73606(-) (comA) [Leuconostoc mesenteroides strain WiKim0121]
ATGAGAAAGTTTCATTATATATCACAACTTGAAGAAAAAGATTGTGGCGTAGCAGCACTAGCTATGATTTTAAAGCGACA
CGGCTCAGATGTTTCATTAGCTAACATTCGTGAACGCTGTCAAACATCCCTATCGGGTACAACGGCGCTAGGCTTAGTGA
AGGCCGCTGAATCATTCAATATGGATGTCCGTCCTATTCAAGCTGACCTTACCTTATTCAACATGAAAGATTTGCCTCTG
CCGTTCATCGCTCATGTTGAGAAAAAAGGTCAATATTTGCATTATTATGTAGTGTACGGATTCACTAAAAACAAAGTTAT
CATTGCAGATCCAGATCCAACAGTTGCTAAAACCGCAATGACGTTACAAGAATTCTCTAAAGAGTGGACTGGTGTAGCAT
TGTTCATGTCGCCTTCACCCAGATATAAACCTTTTAAAGAAAATAAAAACAGTATCCTATCCTTTCTGCCAATTATTAGT
CGACAAAAAGGATTAATTGCTAATATTGTCGTCGCTTCTTTGCTAGTCACTTTAATTAGTATCGCTGGCTCTTATTATAT
GCAACTAGTGATTGATGCTTATATTCCTAGTGCTATGTCTAACACATTAACCGTTGTTTCATTAGGACTCATTGCCACCT
ATGTGTTACAACAGCTACTTAGTTTTGCTCGCACCTATCTGTTAACTATTATGGGACAACGATTATCGATTGAAGTCATA
CTATCATACATACGGCACTTGTTCGAATTACCTGTTAATTTCTTTGCCACACGTCGAACAGGTGAAATTGTCACGCGTTT
TAATGACGCCAACACCATTATTGATGCCATGGCAAATACAATTCTCTCACTTTTTTTAGATTTAGGTATCACGATAATTG
TTGGCAGCGTCTTAGCAATTCAAAATACAAAACTTTTTCTGCTATCTCTAATCTCTTTTCCTATCTACTTCTTGATTGTC
TATTGTTTCATGAAGCCATTTGAACGATTGAATCAAGAACAGATGGCAAGTAATGCAACGCTGAGCTCATCTATTATTGA
AGACATCAATGGTATTGAAACCATAAAATCTTTGACAAGCGAGAAGACGAGCTACCAAAAAATTGATCGTGAATTTGTCG
ATTATTTAAAAAAATCCTTTGCCCATCAAAAAAGCGAAGCCATTCAAAATAGTATTAAACAAGCAACTCAACTCATTATC
AATGTGCTCGTTTTATGGTTGGGTGCCAAGCTAGTGATTAGTAATCAAATTAGTGTCGGTCAGTTAGTTACCTATAATGC
ATTACTAGGCTACTTTACTGAACCTTTCCAAAATATTATTAACTTGCAGGCGAAATTACAAACGGCAACGGTTGCTAACC
GACGATTAAACGAAGTCTATCTTGTAAAATCAGAGTTTAAAAAATCAGAATCACAAGAGCTTCATCATAACAACCCTCAT
AACATTATAGTTGACGACGTCAGCTATCAATATGGTTATCAAAAGAACATATTACACCACTTTTCAATTAAGATCCCCTT
TGGTGAAAAAATTGCTCTGGTCGGTGTTAGCGGTTCCGGTAAGTCAACATTAGCCAAACTACTTGTTCATTTTATATCTC
CTAGTGCTGGCAACATTTTTATTGGTGAACAAAACATTAAACACGTTCAACGACAAAATTTAAGGCAACATATTCTTTAT
CTACCACAAAACCCATACATATTTACTGGAAGCATATTAGATAATTTAACACTAGGTGCTCGTGAAAATACAACACAAGA
AGACATCCTACATGCTGTTGAGCTTGCTGACATTAAAGATGACATCGAAAATATGCCACAAAGTTATCAAACCGAAATTT
CAGAGGAAGGCGGCATGTCTGGAGGCCAAAAGCAGCGTATCGCTTTAGCTAGAGCCCTCCTTAGTAATTCTCAAATACTT
ATTTTGGATGAATCAACCAGTAATCTTGATGTCGCAACTGAAAAAAAGATTATTGATAATTTATTATCGCTTAAAAATAA
AACAATCATTTTTATTGCACATCGCCTGACTATTGCTGAAAAAGTCCAACGCGTTATTCTGCTTGAAAAAGGGATCATCA
GTGAAGATGGTAGCCATGCTGAACTTATACATAAAAAATCAAAATACTATCATCTTGTAAAGCATTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (168-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	59.944	99.86	0.599
comA	Streptococcus mitis NCTC 12261	58.146	99.58	0.579
comA	Streptococcus mitis SK321	57.865	99.58	0.576
comA	Streptococcus pneumoniae Rx1	57.584	99.58	0.573
comA	Streptococcus pneumoniae D39	57.584	99.58	0.573
comA	Streptococcus pneumoniae R6	57.584	99.58	0.573
comA	Streptococcus pneumoniae TIGR4	57.303	99.58	0.571
comA/nlmT	Streptococcus mutans UA159	54.29	99.441	0.54