Detailed information NTG0695335

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: NCY29_RS12255
• Genome accession: NZ_CP098411
• Coordinates: 2548693..2550885 (-)
• Length: 730 a.a.
• NCBI ID: WP_250786011.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei strain 401
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2543693..2555885

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NCY29_RS12225 (NCY29_12225)	-	2543858..2544142 (-)	285	WP_063557690.1	bacteriocin immunity protein	-
NCY29_RS12230 (NCY29_12230)	-	2544336..2544632 (-)	297	WP_063557689.1	bacteriocin immunity protein	-
NCY29_RS12235 (NCY29_12235)	-	2544734..2546089 (-)	1356	WP_003567335.1	threonine/serine exporter family protein	-
NCY29_RS12240 (NCY29_12240)	-	2546395..2546706 (-)	312	WP_003580849.1	hypothetical protein	-
NCY29_RS12245 (NCY29_12245)	-	2546779..2547129 (-)	351	WP_003567340.1	hypothetical protein	-
NCY29_RS12250 (NCY29_12250)	-	2547303..2548682 (-)	1380	WP_063557688.1	bacteriocin secretion accessory protein	-
NCY29_RS12255 (NCY29_12255)	comA	2548693..2550885 (-)	2193	WP_250786011.1	peptide cleavage/export ABC transporter	Regulator
NCY29_RS12260 (NCY29_12260)	-	2551351..2551488 (-)	138	WP_003571414.1	hypothetical protein	-
NCY29_RS12265 (NCY29_12265)	-	2551678..2552976 (+)	1299	WP_063557686.1	GHKL domain-containing protein	-
NCY29_RS12270 (NCY29_12270)	-	2552981..2553787 (+)	807	WP_003567351.1	LytTR family DNA-binding domain-containing protein	-
NCY29_RS12275 (NCY29_12275)	-	2554147..2554344 (-)	198	WP_042753684.1	hypothetical protein	-
NCY29_RS12280 (NCY29_12280)	-	2554891..2555130 (+)	240	WP_003567354.1	hypothetical protein	-
NCY29_RS12285 (NCY29_12285)	-	2555390..2555563 (-)	174	WP_032675994.1	bacteriocin	-
NCY29_RS12290 (NCY29_12290)	-	2555598..2555786 (-)	189	WP_003567358.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81250.46 Da
• Isoelectric Point: 7.0227

>NTDB_id=695335 NCY29_RS12255 WP_250786011.1 2548693..2550885(-) (comA) [Lacticaseibacillus paracasei strain 401]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTSLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPVIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHTELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=695335 NCY29_RS12255 WP_250786011.1 2548693..2550885(-) (comA) [Lacticaseibacillus paracasei strain 401]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGTTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGGACGACGGCATTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCGGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTACGTGGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATACTAGCGCGACAAAAAGGAATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAT
CTTTGGGAATGATTGCCAGTGGCCTCATCCTCGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAAATTGTGTCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACAATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATATTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTGACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGTGTTCCCATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGGTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCAGGTGGACAAAAGCAG
CGCCTAGCCATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCAATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGACCATGGTGCGATTGTTGAACAAGGAAATCATACTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

• Peptidase C39 family (Peptidase_C39) (16-152)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.774	98.356	0.578
comA	Streptococcus pneumoniae Rx1	58.217	98.356	0.573
comA	Streptococcus pneumoniae D39	58.217	98.356	0.573
comA	Streptococcus pneumoniae R6	58.217	98.356	0.573
comA	Streptococcus mitis SK321	58.078	98.356	0.571
comA	Streptococcus pneumoniae TIGR4	57.799	98.356	0.568
comA	Streptococcus gordonii str. Challis substr. CH1	56.964	98.356	0.56
comA/nlmT	Streptococcus mutans UA159	54.848	98.904	0.542