Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   O6U12_RS17815 Genome accession   NZ_CP114899
Coordinates   3347246..3348448 (+) Length   400 a.a.
NCBI ID   WP_017695783.1    Uniprot ID   -
Organism   Bacillus subtilis strain     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3342246..3353448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6U12_RS17795 (O6U12_17795) walK 3342327..3344162 (+) 1836 WP_017695786.1 cell wall metabolism sensor histidine kinase WalK -
  O6U12_RS17800 (O6U12_17800) walH 3344152..3345519 (+) 1368 WP_026113653.1 WalRK two-component regulatory system regulator WalH -
  O6U12_RS17805 (O6U12_17805) walI 3345506..3346348 (+) 843 WP_017695784.1 WalRK two-component regulatory system regulator WalI -
  O6U12_RS17810 (O6U12_17810) vicX 3346370..3347164 (+) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  O6U12_RS17815 (O6U12_17815) htrA 3347246..3348448 (+) 1203 WP_017695783.1 serine protease HtrC Regulator
  O6U12_RS17820 (O6U12_17820) - 3348468..3348598 (+) 131 Protein_3451 hypothetical protein -
  O6U12_RS17825 (O6U12_17825) - 3348626..3348778 (+) 153 Protein_3452 ATP-binding protein -
  O6U12_RS17830 (O6U12_17830) rocR 3348760..3350145 (-) 1386 WP_269767302.1 arginine utilization regulatory protein RocR -
  O6U12_RS17835 (O6U12_17835) rocD 3350383..3351588 (+) 1206 WP_041337907.1 ornithine aminotransferase -
  O6U12_RS17840 (O6U12_17840) rocE 3351811..3353214 (+) 1404 WP_017695780.1 amino acid permease -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42885.74 Da        Isoelectric Point: 5.5235

>NTDB_id=694091 O6U12_RS17815 WP_017695783.1 3347246..3348448(+) (htrA) [Bacillus subtilis strain]
MVNYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGVLDQQQNNNGRESIRTVNVSVNNAATK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVPADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWYETLKLPK
NVTNGVVVMGVDAFSPAAKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDWVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=694091 O6U12_RS17815 WP_017695783.1 3347246..3348448(+) (htrA) [Bacillus subtilis strain]
ATGGTGAATTATGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
TCTTAGATCAGCAGCAAAACAACAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGCCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCAGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGATCGCGTGTACCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGTATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGTGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGCAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACT
GGGTGAAGGTGAAGTTTTATCGCGGCGGAAAAGAAAAATCTGTTGATATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(218-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.434

99

0.43
  htrA Streptococcus mitis NCTC 12261

43.523

96.5

0.42
  htrA Streptococcus gordonii str. Challis substr. CH1

41.397

100

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378