Detailed information NTG0069315

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: MDRSPN_RS05480
• Genome accession: NZ_AP018391
• Coordinates: 1062496..1064736 (-)
• Length: 746 a.a.
• NCBI ID: WP_000942405.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain MDRSPN001
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1057496..1069736

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MDRSPN_RS05445 (MDRSPN_01038)	-	1058399..1058779 (-)	381	WP_000157154.1	VOC family protein	-
MDRSPN_RS05450 (MDRSPN_01039)	rplT	1058837..1059196 (-)	360	WP_120164221.1	50S ribosomal protein L20	-
MDRSPN_RS05455 (MDRSPN_01040)	rpmI	1059248..1059448 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
MDRSPN_RS05460 (MDRSPN_01041)	infC	1059481..1060011 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
MDRSPN_RS05465 (MDRSPN_01042)	-	1060322..1061506 (-)	1185	WP_000655961.1	membrane protein	-
MDRSPN_RS05470 (MDRSPN_01043)	-	1061510..1062097 (-)	588	WP_000939881.1	ATP-binding cassette domain-containing protein	-
MDRSPN_RS11605	-	1062130..1062347 (-)	218	Protein_1049	hypothetical protein	-
MDRSPN_RS05480 (MDRSPN_01044)	comEC/celB	1062496..1064736 (-)	2241	WP_000942405.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
MDRSPN_RS05485 (MDRSPN_01045)	comEA/celA/cilE	1064720..1065370 (-)	651	WP_000387336.1	ComEA family DNA-binding protein	Machinery gene
MDRSPN_RS05490 (MDRSPN_01046)	-	1065438..1066007 (-)	570	WP_000443774.1	GNAT family N-acetyltransferase	-
MDRSPN_RS11250	ald	1066184..1067295 (+)	1112	Protein_1053	alanine dehydrogenase	-
MDRSPN_RS05510 (MDRSPN_01049)	-	1067596..1067922 (-)	327	Protein_1054	TfoX/Sxy family protein	-
MDRSPN_RS05515 (MDRSPN_01050)	-	1067925..1068425 (-)	501	WP_000566986.1	GNAT family N-acetyltransferase	-
MDRSPN_RS05525 (MDRSPN_01051)	-	1068618..1069586 (-)	969	WP_000658183.1	PhoH family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84537.15 Da
• Isoelectric Point: 9.6382

>NTDB_id=69315 MDRSPN_RS05480 WP_000942405.1 1062496..1064736(-) (comEC/celB) [Streptococcus pneumoniae strain MDRSPN001]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKTEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKQFMVELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=69315 MDRSPN_RS05480 WP_000942405.1 1062496..1064736(-) (comEC/celB) [Streptococcus pneumoniae strain MDRSPN001]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGTATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAACCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CACAGAGAAGCTTGATACCCTATCTTAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
GAACATGTCGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGGCAGTTTGAAGCA
GAAGCAATTTATGGTAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	97.587	100	0.976
comEC/celB	Streptococcus pneumoniae D39	97.587	100	0.976
comEC/celB	Streptococcus pneumoniae R6	97.587	100	0.976
comEC/celB	Streptococcus pneumoniae Rx1	97.587	100	0.976
comEC/celB	Streptococcus mitis NCTC 12261	91.812	99.866	0.917
comEC/celB	Streptococcus mitis SK321	91.555	100	0.916
comEC	Lactococcus lactis subsp. cremoris KW2	44.265	99.33	0.44