Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   M9H69_RS07855 Genome accession   NZ_CP097843
Coordinates   1536651..1538540 (-) Length   629 a.a.
NCBI ID   WP_250315320.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1531651..1543540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS07835 (M9H69_07835) - 1532785..1534059 (-) 1275 WP_250315319.1 hydroxymethylglutaryl-CoA reductase, degradative -
  M9H69_RS07840 (M9H69_07840) - 1534059..1535231 (-) 1173 WP_250316177.1 hydroxymethylglutaryl-CoA synthase -
  M9H69_RS07845 (M9H69_07845) - 1535350..1535805 (-) 456 WP_000176910.1 threonine/serine exporter family protein -
  M9H69_RS07850 (M9H69_07850) - 1535807..1536565 (-) 759 WP_096421772.1 threonine/serine exporter family protein -
  M9H69_RS07855 (M9H69_07855) stkP 1536651..1538540 (-) 1890 WP_250315320.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  M9H69_RS07860 (M9H69_07860) - 1538537..1539277 (-) 741 WP_000401532.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  M9H69_RS07865 (M9H69_07865) rsmB 1539293..1540606 (-) 1314 WP_250315321.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M9H69_RS07870 (M9H69_07870) fmt 1540599..1541534 (-) 936 WP_250315322.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 629 a.a.        Molecular weight: 68410.70 Da        Isoelectric Point: 9.2737

>NTDB_id=692941 M9H69_RS07855 WP_250315320.1 1536651..1538540(-) (stkP) [Streptococcus oralis strain HP01]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHARGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEILTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYMDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQSK
KPTQPVAEPAPAPKPAKKRKFKARYMILLASLLLVAASLVWILSRTPATIPIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSDRKEGTKVNLIVSSGKKSFQLSNYVGRKYTDVVAELKGKKVPENLIKMEEEESSESEPGTI
LRQSPAAGTTYDLSKASTITLTVAKKVTSVSMPSYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTAEGTVVDQTP
KAGEKVDLASTRIKLSIYKPKTPPSTSSSNSAQRGNQSSSSTPNQGNQQGNTPSTSQSNSEGTRESSRD

Nucleotide


Download         Length: 1890 bp        

>NTDB_id=692941 M9H69_RS07855 WP_250315320.1 1536651..1538540(-) (stkP) [Streptococcus oralis strain HP01]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGATGGGGAAGAAGTGGCAGTTAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAGCGGGAAGCGAGGGCTATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGATGGCCAACAGTACCTAGCTATGGAATACGTAGCAGGACTCGACCTCAAGCGTTATATCAAAGAACACTATCC
TCTTTCAAATGAAGAAGCGGTTCGGATTATGGGACAGATTCTTTTGGCTATGCGTTTAGCTCATGCTAGAGGAATTGTTC
ACCGAGATTTGAAACCTCAAAATATCCTCTTGACACCAGATGGAACTGCTAAAGTTACTGACTTTGGGATTGCAGTGGCC
TTTGCAGAGACGAGTCTGACCCAGACCAACTCGATGCTGGGTTCGGTTCATTATTTGTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACTTTCCAGAGCGATATCTATGCGATGGGGATTATCTTCTATGAGATTCTGACGGGACATATCCCTTATGATG
GAGATAGCGCGGTTACGATTGCACTCCAGCATTTCCAGAAGCCACTTCCGTCCGTCATTGCTGAAAATCCATCTGTCCCT
CAGGCTTTGGAAAATGTTGTCATCAAGGCAACTGCTAAGAAATTGTCTGATCGCTATCAGTCTGTTTCAGAAATGTATAT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGGAATGAACCGAAACTGGTCTTTGACGATGCGAGTAAGGCGGATACGA
AGACTTTACCTAAAGTCCCACAAAGTACATTGACCTCGATTCCAAAAGCTCCGGCGCAGGAAGAACGTCCTCAGTCAAAG
AAACCAACTCAACCAGTGGCAGAACCGGCTCCAGCGCCAAAACCTGCCAAGAAACGGAAGTTTAAGGCTCGCTATATGAT
TCTTTTGGCCAGTCTTCTATTGGTTGCAGCCTCTTTGGTCTGGATTTTGTCTAGAACACCTGCAACGATTCCTATTCCTG
ATGTGGCTGGACAAACTGTTGCAGAGGCCAAAGAAGCACTCAAAAAATCTAAGTTTGAAGCTGGTGAGGAGAAATCTGAA
GCTAGTGATACAGTAGCGGAAGGACGCGTTATTCGAACCGATCCTGAAGCTGGCAGCGACCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGTAAGAAATCCTTCCAATTGAGTAATTACGTCGGACGCAAGTATACGGATGTCGTAGCTG
AACTCAAGGGGAAGAAGGTTCCTGAGAATCTAATCAAGATGGAAGAGGAGGAATCCAGCGAAAGCGAACCTGGAACCATT
CTCAGACAAAGTCCTGCGGCAGGTACGACTTATGATCTTTCAAAAGCCAGCACAATTACTTTAACGGTTGCTAAGAAAGT
AACAAGTGTTTCTATGCCAAGTTATATTGGTTCAAGTCTCGAATTTACAAAGAATAATTTAACTCAGATTGTCGGTGTAA
AAGAGGCCAATATTGAGGTTGTCGAAGTTTCGACTGCTCCTGAAGGCACAGCAGAAGGTACAGTTGTAGATCAAACACCA
AAAGCGGGTGAAAAGGTTGACCTTGCTAGCACGCGTATCAAACTTTCCATCTACAAACCGAAAACACCACCGTCAACTTC
ATCTTCTAATTCTGCACAGCGTGGGAACCAAAGTTCTTCTTCAACTCCAAATCAGGGGAACCAACAAGGAAACACTCCTT
CAACTAGTCAATCAAATAGTGAAGGAACGCGTGAAAGTTCTCGAGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(372-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

72.644

100

0.76
  stkP Streptococcus pneumoniae D39

72.188

100

0.755
  stkP Streptococcus pneumoniae R6

72.188

100

0.755
  stkP Streptococcus pneumoniae Rx1

72.036

100

0.754
  pknB Streptococcus mutans UA159

56.153

91.733

0.515
  stkP/pknB Streptococcus salivarius strain HSISS4

53.925

93.164

0.502