Detailed information NTG0692933

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: M9H69_RS06345
• Genome accession: NZ_CP097843
• Coordinates: 1228401..1230641 (-)
• Length: 746 a.a.
• NCBI ID: WP_250315111.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain HP01
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1223401..1235641

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H69_RS06315 (M9H69_06315)	-	1224571..1225557 (-)	987	WP_250315109.1	dihydroorotate dehydrogenase	-
M9H69_RS06320 (M9H69_06320)	-	1225520..1226320 (-)	801	WP_250315110.1	dihydroorotate dehydrogenase electron transfer subunit	-
M9H69_RS06325 (M9H69_06325)	-	1226568..1226948 (-)	381	WP_000157148.1	VOC family protein	-
M9H69_RS06330 (M9H69_06330)	rplT	1227007..1227366 (-)	360	WP_000124834.1	50S ribosomal protein L20	-
M9H69_RS06335 (M9H69_06335)	rpmI	1227418..1227618 (-)	201	WP_001125942.1	50S ribosomal protein L35	-
M9H69_RS06340 (M9H69_06340)	infC	1227651..1228181 (-)	531	WP_000848184.1	translation initiation factor IF-3	-
M9H69_RS06345 (M9H69_06345)	comEC/celB	1228401..1230641 (-)	2241	WP_250315111.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
M9H69_RS06350 (M9H69_06350)	comEA/celA/cilE	1230625..1231275 (-)	651	WP_250315113.1	helix-hairpin-helix domain-containing protein	Machinery gene
M9H69_RS06355 (M9H69_06355)	-	1231342..1231911 (-)	570	WP_084875437.1	GNAT family N-acetyltransferase	-
M9H69_RS06360 (M9H69_06360)	ald	1232088..1233200 (+)	1113	WP_250315115.1	alanine dehydrogenase	-
M9H69_RS06365 (M9H69_06365)	-	1233258..1234244 (-)	987	WP_250315116.1	PhoH family protein	-
M9H69_RS06370 (M9H69_06370)	-	1234325..1234540 (-)	216	WP_009066924.1	YozE family protein	-
M9H69_RS06375 (M9H69_06375)	-	1234564..1235142 (-)	579	WP_250315118.1	GrpB family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84646.82 Da
• Isoelectric Point: 9.1419

>NTDB_id=692933 M9H69_RS06345 WP_250315111.1 1228401..1230641(-) (comEC/celB) [Streptococcus oralis strain HP01]
MLQWIKNFPIPLIYLSFLLLWLYYAIFGASYLALLGFVFLLVCLFFQFPWKSASRVLAICGLFGFWFLFQTWQQTQASQD
LVAYVEKVRIFPDTIKVNGDSLSFRGKADGRTFQVYYKLQSEEEKEHFQALTDLHEIELEGKLSEPEGQRNFGGFDYQAY
LKTQGIYQTLTIKSIQSLKKVSSWDIGENLSALRRRAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGYKGLDNFALTVLALFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPLLSFYFAEFQPWSILLTLVFSFLFDLVFLPLLSI
LFILSFVYPVTQLNLVFEWLEDIIRLVSQMASRPLVFGQPNAWLLILLLVSLALVYDFRKNIKRVAGFSLFIVGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIEDWQEKSTTSNAQRTLIPYLKSRGVSKIDHLILTNTDK
EHVGDLLEMTKAFHVGETLVSKGSLTQKEFVAELQATQTKVRSVTAGENLPIFGGYLGVLSPRKIGDGSYDDSLLLYGKL
LDKHFLFTGNLKEKGEKELLKQYPTLEVDILKAGQHGSKTSSSPAFLEKLKPQITLISVGKNNSAKLPHQETLERLESIK
SKIYRTDQNGAIRFKGWNSWRMESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=692933 M9H69_RS06345 WP_250315111.1 1228401..1230641(-) (comEC/celB) [Streptococcus oralis strain HP01]
ATGTTACAGTGGATTAAGAATTTCCCTATCCCCCTAATCTATCTGAGTTTTCTGTTACTCTGGCTTTACTACGCCATTTT
TGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTCGTCTGTCTCTTTTTCCAATTTCCTTGGAAATCGGCTA
GTAGAGTTCTAGCGATTTGTGGACTCTTTGGCTTTTGGTTTCTGTTTCAAACTTGGCAACAGACACAAGCTAGTCAAGAC
TTAGTCGCTTATGTTGAAAAGGTGAGGATTTTTCCAGATACTATCAAAGTCAATGGAGATAGCCTGTCCTTTCGGGGCAA
GGCCGACGGACGCACCTTCCAAGTTTACTATAAACTCCAGTCCGAGGAAGAGAAAGAGCACTTTCAGGCCTTAACAGATC
TTCATGAGATTGAACTAGAAGGAAAACTGTCCGAGCCAGAAGGGCAGAGGAATTTTGGTGGATTTGACTACCAAGCCTAT
CTGAAAACTCAAGGGATTTACCAGACACTGACTATCAAGAGCATCCAGTCACTTAAAAAAGTTAGCAGTTGGGATATAGG
TGAAAATTTGTCGGCTTTACGTCGAAGGGCTGTAGTTTGGATCAAGACGCACTTTCCAGACCCTATGCGCAATTATATGA
CGGGGCTCTTGCTGGGACATTTGGACACGGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCATCTC
TTTGCCTTGTCGGGTATGCAGGTGGGCTTTTTCATGGATGCCTTTAAGAAACTCCTCTTACGATTGGGCTTGACCCAAGA
AAAGTTGAAGTGGCTGACTTATCCCTTTTCTCTTATCTATGCTGGTCTGACAGGATTTTCAGCATCGGTCATTCGCAGTC
TCTTGCAAAAGTTACTGGCCCAACATGGCTACAAGGGCTTGGATAATTTTGCCTTAACAGTCCTTGCCCTCTTTATCATC
ATGCCCAACTTTTTCTTGACAGCTGGAGGGGTTTTGTCCTGTGCCTACGCCTTTATCTTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCCAGAGAAAGTCTGGTCATTTCTTTAGGAATATTGCCCCTTTTATCCTTCTATTTTGCAG
AATTTCAACCTTGGTCAATTCTCTTAACCCTTGTCTTTTCCTTTCTGTTTGACTTGGTATTCTTACCACTTTTGTCCATC
TTATTCATCCTGTCTTTTGTTTACCCAGTCACTCAGCTTAACCTTGTCTTTGAATGGTTGGAGGACATCATTCGCTTGGT
ATCGCAGATGGCAAGCAGGCCCTTGGTCTTTGGACAACCCAACGCATGGCTTTTGATTCTACTCTTAGTTTCATTGGCCT
TGGTCTATGACTTTAGGAAAAATATCAAAAGAGTAGCAGGGTTCAGCCTCTTTATAGTGGGACTCTTTTTCTTAACCAAA
CACCCGCTGGAAAATGAAATCACCATGCTGGATGTAGGGCAGGGAGAAAGCATTTTTCTACGGGATGTAACTGGTAAAAC
CATTCTCATAGATGTGGGCGGAAAGGCAGAATCTGATAAGAAAATAGAGGATTGGCAAGAAAAATCGACGACTAGCAATG
CCCAGAGGACCTTGATTCCCTATCTGAAAAGTCGCGGAGTATCCAAAATTGATCACTTAATTCTGACCAACACAGATAAA
GAACATGTTGGAGATTTGCTGGAGATGACCAAGGCTTTCCATGTCGGGGAAACTTTAGTATCAAAGGGAAGTCTGACACA
AAAGGAATTTGTAGCGGAACTACAAGCGACTCAAACCAAGGTGCGCAGTGTGACAGCAGGGGAGAACTTACCAATTTTTG
GCGGTTACTTAGGAGTCCTATCTCCAAGGAAGATTGGAGATGGAAGTTATGATGATTCTCTCCTTCTTTATGGAAAACTC
TTGGATAAGCACTTTCTCTTTACTGGAAATTTGAAGGAGAAGGGAGAGAAAGAACTTTTAAAGCAATACCCTACCTTAGA
GGTGGATATCTTGAAGGCAGGTCAACATGGTTCAAAGACTTCATCTAGTCCAGCTTTTTTAGAGAAGCTCAAACCGCAAA
TTACTCTCATTTCAGTGGGCAAGAACAATAGTGCCAAACTACCTCATCAGGAAACCTTGGAACGACTAGAAAGCATCAAG
AGTAAGATTTACCGAACTGACCAGAACGGAGCCATTCGCTTTAAAGGATGGAATAGTTGGCGAATGGAAAGTGTTCGATA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-457)

• Domain of unknown function (DUF4131) (DUF4131) (30-177)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	87.919	99.866	0.878
comEC/celB	Streptococcus mitis SK321	87.534	100	0.875
comEC/celB	Streptococcus pneumoniae TIGR4	86.059	100	0.861
comEC/celB	Streptococcus pneumoniae Rx1	85.657	100	0.857
comEC/celB	Streptococcus pneumoniae D39	85.657	100	0.857
comEC/celB	Streptococcus pneumoniae R6	85.657	100	0.857
comEC	Lactococcus lactis subsp. cremoris KW2	44.265	99.33	0.44