Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   M9H69_RS04010 Genome accession   NZ_CP097843
Coordinates   764877..765617 (+) Length   246 a.a.
NCBI ID   WP_250316168.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 759877..770617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS04000 (M9H69_04000) - 760522..763230 (+) 2709 WP_250315981.1 MBL fold metallo-hydrolase -
  M9H69_RS04005 (M9H69_04005) - 763276..764754 (-) 1479 WP_000789709.1 oligosaccharide flippase family protein -
  M9H69_RS04010 (M9H69_04010) mecA 764877..765617 (+) 741 WP_250316168.1 adaptor protein MecA Regulator
  M9H69_RS04015 (M9H69_04015) - 765765..767051 (+) 1287 WP_250315982.1 homoserine dehydrogenase -
  M9H69_RS04020 (M9H69_04020) thrB 767053..767922 (+) 870 WP_250315983.1 homoserine kinase -
  M9H69_RS04025 (M9H69_04025) - 767999..768145 (+) 147 WP_250315984.1 hypothetical protein -
  M9H69_RS04030 (M9H69_04030) msrB 768174..769112 (+) 939 WP_250315985.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28470.27 Da        Isoelectric Point: 4.0759

>NTDB_id=692922 M9H69_RS04010 WP_250316168.1 764877..765617(+) (mecA) [Streptococcus oralis strain HP01]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETEIKKEPYIYYILRFA
SLSDLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVIG
LQKISS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=692922 M9H69_RS04010 WP_250316168.1 764877..765617(+) (mecA) [Streptococcus oralis strain HP01]
ATGAAGATGAAACAAATTAGTGATACAACACTAAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAATTAGAAATGCCAGACAATT
TCTTGGATAGTGGCATGTTGAGTTTCCGTGTGACTCCAAAACCAGATAAGGTGGACGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATCTGGATTTTGAAGATTTGGCGGATTTACCCGATATGGAAGAATTAGCCCAAATGTCACCAGATGAATTCCT
CAAAACCTTAGAAAAGAGCATTGCAGACAAGACCAAGGACGATATTGAGGCTATCCAGTCCCTAGAACAGGTCGAGGCTA
AAGAAGAGGAGCAAGAACAGGCAGATAAGGAGACTGAGATCAAGAAGGAACCTTATATCTACTATATCTTGCGTTTTGCA
AGCCTTTCTGACCTAGTTGCTTTTGCAAAGACTGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGACA
TTACTACTTGACGATTTTAGTCGATGTGGAAAATCATCCTAGTCCATATCCAGCCTGGCTCTTGGCCCGTATGCGCGAAT
TTGCAGATGATAGTGACATCAGTCGCTCAGTCTTGCAAGAGTATGGGCAAATCTTGATCAATCACGACGCAGTTATCGGT
CTGCAAAAGATTAGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

89.388

99.593

0.89
  mecA Streptococcus pneumoniae D39

89.388

99.593

0.89
  mecA Streptococcus pneumoniae R6

89.388

99.593

0.89
  mecA Streptococcus pneumoniae TIGR4

88.98

99.593

0.886
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.484
  mecA Streptococcus thermophilus LMG 18311

47.791

100

0.484
  mecA Streptococcus mutans UA159

48.163

99.593

0.48