Detailed information NTG0692895

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: M9H69_RS00480
• Genome accession: NZ_CP097843
• Coordinates: 71272..73425 (+)
• Length: 717 a.a.
• NCBI ID: WP_084920041.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain HP01
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 66272..78425

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H69_RS00435 (M9H69_00435)	-	66332..67501 (+)	1170	WP_000366366.1	pyridoxal phosphate-dependent aminotransferase	-
M9H69_RS00440 (M9H69_00440)	recO	67498..68268 (+)	771	WP_084938702.1	DNA repair protein RecO	-
M9H69_RS00445 (M9H69_00445)	plsX	68265..69257 (+)	993	WP_247941856.1	phosphate acyltransferase PlsX	-
M9H69_RS00450 (M9H69_00450)	-	69261..69497 (+)	237	WP_000136450.1	acyl carrier protein	-
M9H69_RS00455 (M9H69_00455)	-	69941..70132 (+)	192	WP_000180812.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
M9H69_RS00460 (M9H69_00460)	-	70157..70339 (+)	183	WP_009729537.1	Blp family class II bacteriocin	-
M9H69_RS00465 (M9H69_00465)	-	70343..70567 (+)	225	WP_080585587.1	bacteriocin immunity protein	-
M9H69_RS00470 (M9H69_00470)	-	70639..70827 (+)	189	WP_195217117.1	hypothetical protein	-
M9H69_RS00475 (M9H69_00475)	-	70852..71061 (+)	210	WP_000869800.1	hypothetical protein	-
M9H69_RS00480 (M9H69_00480)	comA	71272..73425 (+)	2154	WP_084920041.1	peptide cleavage/export ABC transporter ComA	Regulator
M9H69_RS00485 (M9H69_00485)	comB	73438..74787 (+)	1350	WP_250315623.1	competence pheromone export protein ComB	Regulator
M9H69_RS00490 (M9H69_00490)	purC	74957..75664 (+)	708	WP_250315624.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80329.66 Da
• Isoelectric Point: 7.1490

>NTDB_id=692895 M9H69_RS00480 WP_084920041.1 71272..73425(+) (comA) [Streptococcus oralis strain HP01]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVIGQDKKTIHIADPDPSVKLTKICRERFAQEWTGVSLFMAPSPDYKPHREKKQGLLSFLPI
LLKQRGLITNIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNITLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSMM
KGDMAFKQVHYKYGYGRDVLSDINLTIPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQHI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGNHVDLLARGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=692895 M9H69_RS00480 WP_084920041.1 71272..73425(+) (comA) [Streptococcus oralis strain HP01]
ATGAAATTTGGGAAAAGGCACTATCGTCCCCAGGTGGATCAGATGGATTGCGGTGTGGCTTCCTTGGCCATGGTCTTTGG
CTACTATGGTAGTTATTACTCCTTGGCTCACCTGCGAGAGTTAGCCAAGACGACTATGGATGGGACAACTGCTTTGGGTC
TTGTCAAGGTGGCAGAAGAAATTGGCTTCGAGACGCGCGCTATCAAAGCGGATATGACGCTCTTTGATCTGCCTGATTTG
ACTTTTCCTTTTGTAGCCCATGTGCTCAAGGAAGGGAAATTGCTCCACTATTATGTGGTGATTGGTCAGGACAAGAAGAC
GATCCACATCGCTGATCCAGATCCTAGTGTTAAGCTGACGAAGATTTGCCGTGAGCGATTTGCGCAAGAATGGACAGGGG
TCAGTCTCTTTATGGCACCGTCTCCAGACTACAAACCTCACAGGGAGAAAAAACAAGGGCTCCTATCCTTCTTGCCAATC
TTACTCAAACAGCGTGGCTTAATTACCAATATCGTTCTAGCGACACTCTTGGTAACCTTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCGATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGCTGGGGATTATTTCTATTGGGCTGGTCA
TCGTCTATATCCTCCAGCAAATCTTGTCCTATGCGCAGGAATATCTTTTACTTGTTCTGGGGCAACGGTTGTCAATTGAC
GTGATTTTGTCTTATATCAAGCATGTTTTTCACCTGCCAATGTCCTTTTTCGCGACACGCAGGACAGGGGAAATCGTTTC
TCGTTTTACAGATGCTAATAGTATCATTGATGCGCTAGCTTCGACCATTCTTTCTATCTTTTTGGATGTGTCAACGATTT
TGATTATCTCGCTTGTCTTGTTTTCACAAAATATAACACTCTTTTTCATCAGTCTGCTTGCACTTCCCATTTATACAGTG
ATTATATTTGCCTTTATGAAGCCTTTTGAAAAGATGAATCGGGACACTATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGACATCAACGGTATTGAGACCATTAAGTCTTTGACTAGTGAAAGTTCACGCTATCAAAAGATTGATAAGGAAT
TTGTGGCTTATCTGAAAAAATCCTTTACCTACAGTCGGGCAGAAAGCCAGCAAAAGGCTCTGAAAAAAGTTGCCCAGCTT
CTTCTCAATGTTGCCGTTCTTTGGATGGGAGCTGTTCTGGTCATGGATGGCAAGATGAGTTTGGGGCAATTGATTACCTA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATCAACCTGCAAACCAAACTTCAAACAGCGCAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTGGTAGCTTCGGAGTTTGAGGAGAAGAAAACAGTAGAAGATTTGAGCATGATG
AAAGGGGATATGGCTTTCAAGCAGGTTCACTACAAGTATGGCTACGGTCGAGATGTTTTGTCGGATATCAATTTGACCAT
TCCGCAAGGTTCTAAAGTGGCTTTCGTGGGGATTTCAGGGTCAGGCAAGACCACCTTGGCCAAGATGATGGTTAACTTTT
ACGACCCTAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTTAATCAGATTGATAAAAAAGCCTTGCGCCAGCATATC
AACTATTTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
ACAGGAGGATATTCTGCGAGCAGTTGAATTGGCAGAGATTCGGGAGGATATCGAGCGGATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGCGCAGGTATTTCTGGTGGCCAACGGCAGCGAATCGCTCTGGCGCGAGCTCTTTTAACGGATGCA
CCTGTTTTGATATTGGACGAAGCGACCAGCAGTCTGGATATCTTGACAGAGAAGCGGATTGTGGATAATCTTATGGCTTT
AGACAAGACCTTGATTTTCATTGCCCACCGCTTGACCATTGCTGAGCGGACAGAGAAAGTTGTTGTCTTGGATCAGGGCA
AGATTGTCGAAGAGGGAAATCATGTGGACTTACTGGCTCGAGGTGGATTTTACGCCCATTTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	95.397	100	0.954
comA	Streptococcus pneumoniae Rx1	94.979	100	0.95
comA	Streptococcus pneumoniae D39	94.979	100	0.95
comA	Streptococcus pneumoniae R6	94.979	100	0.95
comA	Streptococcus mitis SK321	94.7	100	0.947
comA	Streptococcus pneumoniae TIGR4	94.561	100	0.946
comA	Streptococcus gordonii str. Challis substr. CH1	80.614	100	0.806
comA/nlmT	Streptococcus mutans UA159	64.714	100	0.647