Detailed information NTG0069066

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: STO1_RS05965
• Genome accession: NZ_AP018338
• Coordinates: 1179238..1181478 (-)
• Length: 746 a.a.
• NCBI ID: WP_096422408.1
• Uniprot ID: -
• Organism: Streptococcus oralis subsp. tigurinus strain osk_001
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1174238..1186478

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STO1_RS05935 (STO1_011560)	rplT	1175569..1175928 (-)	360	WP_000124834.1	50S ribosomal protein L20	-
STO1_RS05940 (STO1_011570)	rpmI	1175980..1176180 (-)	201	WP_001125942.1	50S ribosomal protein L35	-
STO1_RS05945 (STO1_011580)	infC	1176213..1176743 (-)	531	WP_007521573.1	translation initiation factor IF-3	-
STO1_RS05950 (STO1_011590)	-	1177058..1178241 (-)	1184	Protein_1164	hypothetical protein	-
STO1_RS05955 (STO1_011610)	-	1178238..1178831 (-)	594	WP_061588100.1	ATP-binding cassette domain-containing protein	-
STO1_RS09920	-	1178863..1179090 (-)	228	WP_061588099.1	hypothetical protein	-
STO1_RS05965 (STO1_011630)	comEC/celB	1179238..1181478 (-)	2241	WP_096422408.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
STO1_RS05970 (STO1_011640)	comEA/celA/cilE	1181462..1182112 (-)	651	WP_061587623.1	helix-hairpin-helix domain-containing protein	Machinery gene
STO1_RS05975 (STO1_011650)	-	1182179..1182748 (-)	570	WP_084939084.1	GNAT family N-acetyltransferase	-
STO1_RS05985 (STO1_011660)	ald	1182925..1184037 (+)	1113	WP_045616943.1	alanine dehydrogenase	-
STO1_RS05990 (STO1_011670)	-	1184087..1185073 (-)	987	WP_000658201.1	PhoH family protein	-
STO1_RS05995 (STO1_011680)	-	1185154..1185369 (-)	216	WP_001232084.1	YozE family protein	-
STO1_RS06000 (STO1_011690)	-	1185393..1185971 (-)	579	WP_061588095.1	GrpB family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84838.92 Da
• Isoelectric Point: 9.3510

>NTDB_id=69066 STO1_RS05965 WP_096422408.1 1179238..1181478(-) (comEC/celB) [Streptococcus oralis subsp. tigurinus strain osk_001]
MSQWIKNFPIPLIYLSFLLLWLYYAIFGVSYLALLGFVFLLICLFFQFSWKSAGKILAICGVFGFWFLFHNWQQTQANQN
LMDSVERVRILPDTIKVNGDSLSFRGKADGRTFQIYYKLQSEEEKEQFQALTDLYEIELEGKLSEPEGQRNFGGFDYQAY
LKTQGIYQTLTIKSIQSLKKVSSWDIGENLSSLRRKAIVWIKSHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKHLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLFQKLLAQHGYKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFAFSFVYPAVQFNLIFEWLEGVIRLVSQLATRPLVFGQPNAWLLILLLVSLALVYDMRKNIKRLAGFSLFIVGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIQAWQQKSTASNAQRTLIPYLKSRGVDKIDQLILTNTEK
EHVGDLLEVTRAFQVGEILVSKGSLTQKEFVAELQATQTKVRSVTGGENLPIFGSYLEVLSTRKMGDGSHDDSLFLYGRL
LDKHFLFTGNLKEKGEKDLLKQYSTLEVDVLKVGQHGSKTSSNLAFLEKLKPEITLISVGKNNRTKLPHQEALTRLETIN
SKIYRTDQNGAIRFKGWKSWQIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=69066 STO1_RS05965 WP_096422408.1 1179238..1181478(-) (comEC/celB) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGTCACAGTGGATTAAGAATTTTCCTATCCCCCTAATCTACCTGAGCTTTCTGTTGCTCTGGCTTTACTATGCCATTTT
TGGAGTGTCCTATCTAGCACTGCTAGGTTTTGTTTTTTTGCTCATCTGTCTCTTTTTCCAATTTTCTTGGAAATCGGCTG
GTAAAATTTTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTTTGTTTCATAACTGGCAACAGACACAAGCTAATCAAAAC
CTAATGGATTCTGTTGAGAGGGTACGGATTTTACCGGATACTATCAAAGTCAATGGAGATAGTCTGTCCTTTCGGGGCAA
GGCTGACGGCCGTACCTTCCAAATTTACTATAAACTCCAGTCCGAGGAAGAGAAAGAGCAATTTCAAGCCTTGACAGACC
TCTATGAGATAGAACTGGAAGGAAAACTGTCAGAGCCAGAAGGCCAGAGAAATTTTGGTGGATTTGACTACCAAGCCTAT
CTGAAAACTCAAGGGATTTACCAGACACTGACTATCAAGAGCATCCAGTCACTTAAAAAAGTTAGCAGTTGGGATATAGG
TGAAAACCTATCGAGTCTACGTAGAAAGGCTATTGTTTGGATTAAGAGCCATTTTCCCGACCCTATGCGTAACTACATGA
CGGGGCTCTTGCTGGGACATCTGGATACGGACTTCGAGGAGATGAATGAGCTCTATTCCAGTCTTGGAATTATCCATCTC
TTTGCCTTGTCGGGTATGCAGGTGGGTTTCTTTATGGATGGTTTTAAGAAACACCTCTTGCGATTGGGCTTGACTCAAGA
AAAGTTGAAGTGGCTGACCTATCCCTTTTCCCTTATCTATGCAGGTCTGACAGGATTTTCAGCATCGGTCATTCGTAGTC
TCTTCCAAAAGTTACTGGCCCAACATGGCTACAAGGGTTTGGACAATTTTGCCTTGACGGTGCTTGTTCTCTTTATCATC
ATGCCCAACTTTTTCCTAACTGCAGGAGGAGTCTTGTCCTGCGCCTACGCCTTTATCTTGACCATGACTAGTAAAGAAGG
CGAGGGGCTCAAGGCTGTTGCCAGAGAAAGTCTGGTCATTTCCTTGGGAATATTGCCCATTCTTTCCTTTTATTTTGCAG
AATTTCAGCCTTGGTCAATTCTTTTAACATTTGTCTTTTCCTTTCTTTTTGACTTGGTTTTCTTACCACTTTTGTCTATC
TTGTTTGCCTTTTCTTTTGTCTATCCTGCCGTTCAATTTAACCTTATCTTTGAGTGGTTGGAGGGCGTCATTCGCTTGGT
TTCACAGCTAGCAACTAGGCCCTTGGTCTTTGGACAACCCAACGCATGGCTTTTGATTCTTCTCTTAGTTTCATTAGCCT
TGGTCTATGACATGAGGAAAAACATCAAAAGACTAGCAGGATTCAGTCTCTTTATCGTAGGACTCTTTTTCTTGACCAAG
CATCCGCTGGAAAATGAAATCACCATGCTGGATGTAGGGCAGGGAGAAAGCATTTTTCTAAGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTGGGTGGAAAGGCAGAATCCGACAAAAAAATCCAAGCTTGGCAGCAAAAGTCGACGGCTAGCAATG
CCCAGCGAACCTTGATTCCCTATCTTAAAAGTCGTGGAGTAGACAAGATTGACCAGCTGATTTTGACCAACACAGAGAAA
GAGCATGTTGGAGATTTACTAGAGGTGACCAGGGCTTTCCAAGTCGGGGAGATTTTAGTATCAAAAGGAAGTTTGACACA
GAAAGAATTTGTGGCAGAACTACAAGCGACTCAAACCAAGGTACGCAGTGTGACAGGGGGGGAGAATTTACCGATTTTTG
GCAGTTACTTAGAAGTCCTATCTACAAGGAAGATGGGAGATGGAAGTCATGATGATTCTCTTTTTCTTTATGGGAGGCTT
TTGGATAAGCACTTTCTCTTTACTGGAAACTTGAAGGAGAAGGGAGAAAAGGATCTTCTAAAGCAATACTCTACCTTAGA
GGTGGATGTCTTAAAAGTCGGTCAACATGGTTCTAAAACCTCATCAAATCTAGCTTTCCTAGAAAAACTCAAACCAGAAA
TTACTCTCATTTCAGTTGGAAAGAACAATCGTACGAAGCTACCCCATCAGGAAGCCTTGACACGACTGGAAACTATCAAT
AGTAAAATTTACCGAACTGACCAGAACGGAGCTATTCGCTTTAAAGGTTGGAAAAGTTGGCAAATCGAAAGTGTTCGTTA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-700)

• Domain of unknown function (DUF4131) (DUF4131) (29-177)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	87.802	100	0.878
comEC/celB	Streptococcus mitis NCTC 12261	87.114	99.866	0.87
comEC/celB	Streptococcus pneumoniae TIGR4	86.059	100	0.861
comEC/celB	Streptococcus pneumoniae Rx1	85.523	100	0.855
comEC/celB	Streptococcus pneumoniae D39	85.523	100	0.855
comEC/celB	Streptococcus pneumoniae R6	85.523	100	0.855
comEC	Lactococcus lactis subsp. cremoris KW2	45.209	99.33	0.449