Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   STO1_RS04645 Genome accession   NZ_AP018338
Coordinates   911958..912665 (+) Length   235 a.a.
NCBI ID   WP_096422160.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 906958..917665
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS04620 (STO1_008930) - 907287..907958 (+) 672 WP_000151555.1 GTP pyrophosphokinase -
  STO1_RS04625 (STO1_008940) - 907942..908760 (+) 819 WP_000799063.1 NAD kinase -
  STO1_RS04630 (STO1_008950) - 908757..909647 (+) 891 WP_096422154.1 RluA family pseudouridine synthase -
  STO1_RS04635 (STO1_008960) pta 909665..910639 (+) 975 WP_096422156.1 phosphate acetyltransferase -
  STO1_RS04640 (STO1_008970) mutY 910723..911898 (+) 1176 WP_096422158.1 A/G-specific adenine glycosylase -
  STO1_RS04645 (STO1_008980) micA 911958..912665 (+) 708 WP_096422160.1 response regulator YycF Regulator
  STO1_RS04650 (STO1_008990) micB 912658..914007 (+) 1350 WP_000568721.1 cell wall metabolism sensor histidine kinase VicK Regulator
  STO1_RS04655 (STO1_009000) vicX 914009..914818 (+) 810 WP_096422162.1 MBL fold metallo-hydrolase Regulator
  STO1_RS04660 (STO1_009010) - 914926..916800 (+) 1875 WP_096422164.1 Eco57I restriction-modification methylase domain-containing protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27019.92 Da        Isoelectric Point: 4.6802

>NTDB_id=69057 STO1_RS04645 WP_096422160.1 911958..912665(+) (micA) [Streptococcus oralis subsp. tigurinus strain osk_001]
MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDSQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRKND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=69057 STO1_RS04645 WP_096422160.1 911958..912665(+) (micA) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAGGAAGGTTATGA
AGTCGTTACAGCCTTCAATGGTCGTGAGGCAATCGAGCTATTTGAAGCTGAGCAACCGGATATTATTATCCTCGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTTGCTAAAGCTATTCGTAAGACTAGTAGCGTGCCGATTATCATGCTATCAGCT
AAGGATAGCGAGTTTGACAAGGTTATTGGTTTAGAGTTAGGTGCAGATGATTATGTTACAAAACCTTTCTCAAACCGTGA
GTTGCAAGCACGAGTCAAGGCCCTACTTCGTCGTACGGATCTAGTTTCTGTGGATAGCCAAGAGTCTGATGAGAAGAAGA
CGCAGCCTTTACAAATTGGTGATTTGGAAATCGTTCCAGATGCTTACGTGGCTAAGAAATATGGTGAGGAATTAGATTTA
ACCCACCGTGAGTTTGAACTCTTGTATCACTTGGCGTCTCATATTGGTCAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTATGGGGTTATGACTATTTTGGTGATGTTCGTACTGTGGACGTGACCATTAGACGCTTGCGTGAGAAAATAGAAGACA
CTCCAAGTCGCCCAGAGTACATTCTCACACGTCGTGGTGTTGGATACTATATGAGAAAAAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

91.88

99.574

0.915
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

43.534

98.723

0.43
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.103

98.723

0.426
  scnR Streptococcus mutans UA159

37.179

99.574

0.37

Multiple sequence alignment