Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   M8286_RS08400 Genome accession   NZ_CP097577
Coordinates   1729035..1729745 (-) Length   236 a.a.
NCBI ID   WP_275600912.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1728356..1729309 1729035..1729745 flank -274


Gene organization within MGE regions


Location: 1728356..1729745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS08400 (M8286_08540) mecA 1729035..1729745 (-) 711 WP_275600912.1 adaptor protein MecA Regulator

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27502.04 Da        Isoelectric Point: 4.0856

>NTDB_id=690349 M8286_RS08400 WP_275600912.1 1729035..1729745(-) (mecA) [Streptococcus suis strain 3112]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEEEADEEEQERYIYYILEFPTIEELFTFVGT
VDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 711 bp        

>NTDB_id=690349 M8286_RS08400 WP_275600912.1 1729035..1729745(-) (mecA) [Streptococcus suis strain 3112]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAGTCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCGCCAGATGCAACAGCCGTTCGTCATTTGGAAGAGGAAGAAGCAG
ATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGAGCTGTTTACTTTTGTTGGTACG
GTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTATCAATGTAGAAAA
TCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACGAAGTTGACCAGACCTGCTT
TACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

50.82

100

0.525
  mecA Streptococcus pneumoniae D39

49.59

100

0.513
  mecA Streptococcus pneumoniae R6

49.59

100

0.513
  mecA Streptococcus pneumoniae Rx1

49.59

100

0.513
  mecA Streptococcus pneumoniae TIGR4

49.59

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.483
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.479