Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   M8286_RS02105 Genome accession   NZ_CP097577
Coordinates   420021..422015 (+) Length   664 a.a.
NCBI ID   WP_275601342.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 415021..427015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS02085 (M8286_02095) - 415955..416788 (-) 834 WP_275601339.1 LysR family transcriptional regulator -
  M8286_RS02090 (M8286_02100) fmt 417008..417946 (+) 939 WP_275601340.1 methionyl-tRNA formyltransferase -
  M8286_RS02095 (M8286_02105) rsmB 417933..419246 (+) 1314 WP_275601341.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  M8286_RS02100 (M8286_02110) - 419284..420021 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  M8286_RS02105 (M8286_02115) stkP 420021..422015 (+) 1995 WP_275601342.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  M8286_RS02110 (M8286_02120) liaF 422303..422998 (+) 696 WP_012774984.1 cell wall-active antibiotics response protein LiaF -
  M8286_RS02115 (M8286_02125) - 422995..424011 (+) 1017 WP_002937028.1 sensor histidine kinase -
  M8286_RS02120 (M8286_02130) - 423983..424624 (+) 642 WP_358638919.1 response regulator transcription factor -
  M8286_RS02125 (M8286_02135) - 424674..426074 (+) 1401 WP_029173958.1 Cof-type HAD-IIB family hydrolase -
  M8286_RS02130 (M8286_02140) - 426076..426447 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71370.92 Da        Isoelectric Point: 6.3011

>NTDB_id=690322 M8286_RS02105 WP_275601342.1 420021..422015(+) (stkP) [Streptococcus suis strain 3112]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVSGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGAGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIAAGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAAMVSIPDVTDKDSDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKTQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQTLGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=690322 M8286_RS02105 WP_275601342.1 420021..422015(+) (stkP) [Streptococcus suis strain 3112]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCCGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGC
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAGTGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTCGCTATGCGAATGGCGCACACAAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTTCTTTTGACTTCCAACGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTCGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGATAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCAAACGTACCA
CAGGCTTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCCCTATCCATGGATCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAGGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCCCAAGTTTCTGCGACGGAT
AAAGGGGCTGGTAAGAAAGAAGTGGCGAAGTCGGGGAATAAGCCTGTTTCAAAACCAAGACCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGGGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTGTCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGAATTGGAGGCTCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGTCTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGGGCAAAAATTACCCTTTACGTTTCCAAAGGAGTAGCGCCACAAGT
TGTGCCAAACGTTGTTGGGAAAACTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGTATTGGAACTATTA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCCGTTGCCAATACAGAGTTGACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCACGTAGTCAATTACAAACACTGGGTGTCAATGTGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGCGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCGGCACCAGTAGCGATTCCTCAACAGGAAGTTCCACTAGCACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-501)

Protein kinase domain (Pkinase)

(12-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

53.241

97.59

0.52
  stkP Streptococcus pneumoniae D39

53.086

97.59

0.518
  stkP Streptococcus pneumoniae R6

53.086

97.59

0.518
  stkP Streptococcus pneumoniae Rx1

52.932

97.59

0.517
  stkP/pknB Streptococcus salivarius strain HSISS4

51.684

89.458

0.462
  pknB Streptococcus mutans UA159

54.953

80.572

0.443