Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   M8286_RS00335 Genome accession   NZ_CP097577
Coordinates   58045..58944 (+) Length   299 a.a.
NCBI ID   WP_275601142.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 53045..63944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS00320 (M8286_00315) - 54786..56054 (+) 1269 WP_275601139.1 MerR family transcriptional regulator -
  M8286_RS00325 (M8286_00320) ruvB 56248..57249 (+) 1002 WP_275601140.1 Holliday junction branch migration DNA helicase RuvB -
  M8286_RS00330 (M8286_00325) - 57317..57952 (+) 636 WP_275601141.1 HAD-IA family hydrolase -
  M8286_RS00335 (M8286_00330) comR 58045..58944 (+) 900 WP_275601142.1 helix-turn-helix domain-containing protein Regulator
  M8286_RS00340 (M8286_00335) - 59152..60372 (+) 1221 WP_275601143.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  M8286_RS00345 (M8286_00340) - 60563..62086 (+) 1524 WP_275601144.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35131.12 Da        Isoelectric Point: 4.5008

>NTDB_id=690306 M8286_RS00335 WP_275601142.1 58045..58944(+) (comR) [Streptococcus suis strain 3112]
MNDKEFGQRVRQLREVANMTREQFCGDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKQKYEVND
LLIIRLQLEYVILSSSDSEIFGQFLKIIEYLHGQIDIINSSDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQLT
QDFQKKPIVSVLKWKYALFVNKDRGEAEKHYLDAMLFAKLIENRELEEKIEEDWKVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=690306 M8286_RS00335 WP_275601142.1 58045..58944(+) (comR) [Streptococcus suis strain 3112]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGCGAAGTAGCTAATATGACGCGTGAACAATTTTGTGGTGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAGGCTGGAACTTCTAAGCCGACTTTTTCAAAAATCCAGTATA
TCGCAACCCGTTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTATCCTTGCCAGAAAGATACTCCAAGCTGAAA
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGATGCTATCATGACGGAAATCTATGA
TGACTATTATGACGACTTGCCTGAAGAGGAGAAAATAGCGATTGATGCCATTCAATCCCGAATTGATACCTTAGAATCAG
GGACAGCAGGCTTTGGAAAAGAGATACTGGAAGATTACTTTGAACAAATTTTTCGAAAACAAAAGTACGAAGTGAATGAT
TTGCTGATTATTAGGCTCCAGCTTGAATACGTTATATTATCCAGTAGTGACTCAGAAATATTTGGACAGTTTTTGAAAAT
TATAGAATATTTACATGGACAAATTGATATTATCAATTCAAGTGATTTATTTGTTCTAAGAGATACATTGTTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTATGAACCAATACCAAAGATATTCGACAGTGTAGATAAAATTATACAGTTAACG
CAAGATTTTCAGAAAAAGCCAATTGTCAGCGTGTTGAAATGGAAGTACGCACTTTTTGTAAATAAGGATAGAGGTGAGGC
TGAAAAGCATTATCTAGATGCGATGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAGGAGAAGATTGAAGAAGATT
GGAAAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

91.639

100

0.916
  comR Streptococcus suis 05ZYH33

91.639

100

0.916
  comR Streptococcus suis D9

60.133

100

0.605
  comR Streptococcus mutans UA159

45.151

100

0.452
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.144

97.324

0.371
  comR Streptococcus pyogenes MGAS315

37.037

99.331

0.368