Detailed information NTG0686730

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: M2904_RS07970
• Genome accession: NZ_CP097053
• Coordinates: 1610132..1611388 (-)
• Length: 418 a.a.
• NCBI ID: WP_248853068.1
• Uniprot ID: -
• Organism: Vagococcus lutrae strain AT15
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1605132..1616388

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M2904_RS07950 (M2904_07950)	walK	1605314..1607140 (+)	1827	WP_248848403.1	cell wall metabolism sensor histidine kinase WalK	-
M2904_RS07955 (M2904_07955)	yycH	1607137..1608441 (+)	1305	WP_248853066.1	two-component system activity regulator YycH	-
M2904_RS07960 (M2904_07960)	-	1608441..1609271 (+)	831	WP_248853067.1	two-component system regulatory protein YycI	-
M2904_RS07965 (M2904_07965)	-	1609289..1610095 (+)	807	WP_126762855.1	MBL fold metallo-hydrolase	-
M2904_RS07970 (M2904_07970)	htrA	1610132..1611388 (-)	1257	WP_248853068.1	trypsin-like peptidase domain-containing protein	Regulator
M2904_RS07975 (M2904_07975)	rlmH	1611725..1612204 (+)	480	WP_248853069.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
M2904_RS07980 (M2904_07980)	-	1612414..1615173 (+)	2760	WP_248853070.1	Z1 domain-containing protein	-

Sequence

Protein

• Length: 418 a.a.
• Molecular weight: 44378.84 Da
• Isoelectric Point: 4.5720

>NTDB_id=686730 M2904_RS07970 WP_248853068.1 1610132..1611388(-) (htrA) [Vagococcus lutrae strain AT15]
MKTYETSTSSPLKRFGTGLLGGLIGGAVAFGLLFNFNQDSDKTSQPLNNHGEATKVEKVAYDVENNTSKAVEKVQGAVVS
VINLQKRQEMADEYGLGGLFGLPQQPEKKSEDKQDELETSSEGSGVIYKKDGKNAYVVTNNHVVEGSDALEVLMNDGSKV
SAELVGADAYTDLAVLKISAEGVKDTAEFGDSDVLKIGEPAIAIGSPLGSDYANSVTQGIISAKNRTITNQNPETGQPTN
INAIQTDAAINPGNSGGPLINIAGQVIGINSIKIARAASGISAEGMGFSIPSNDVVDIINQLEQNGQVIRPMLGVTMIDL
AVISQEQQEKILKLPTDIKSGVIIRSVQAASPAEAAGLKQYDVIVGIDGKEIENATDLQTILYTKKVGDEIEVTYYREHH
KNTVKVSLSLDRSSLEKK

Nucleotide

• Length: 1257 bp

>NTDB_id=686730 M2904_RS07970 WP_248853068.1 1610132..1611388(-) (htrA) [Vagococcus lutrae strain AT15]
ATGAAAACATATGAAACATCTACTTCATCCCCTCTTAAACGTTTTGGAACGGGACTTTTAGGCGGACTCATTGGAGGTGC
CGTCGCGTTTGGTCTTTTATTTAATTTCAATCAAGACAGTGATAAGACATCTCAGCCATTAAACAATCATGGTGAAGCTA
CGAAAGTTGAGAAAGTGGCTTATGATGTGGAAAACAATACTTCTAAAGCCGTGGAGAAAGTACAAGGCGCTGTCGTTTCT
GTCATTAATTTACAAAAACGACAAGAAATGGCGGATGAATATGGACTTGGTGGACTATTCGGTTTACCGCAACAACCCGA
AAAGAAATCAGAAGATAAACAAGACGAGCTCGAAACTTCTAGCGAGGGCAGTGGGGTTATTTATAAAAAAGATGGTAAAA
ACGCCTATGTTGTGACTAATAATCACGTCGTGGAAGGTTCTGATGCTTTAGAAGTTTTAATGAACGACGGTTCAAAAGTG
TCCGCTGAACTAGTTGGTGCCGACGCTTATACTGATTTGGCTGTTTTAAAAATCAGTGCCGAGGGCGTAAAAGATACTGC
TGAATTTGGTGATTCTGATGTTCTAAAAATTGGAGAACCTGCGATTGCGATTGGTTCTCCACTCGGTTCTGATTATGCTA
ACTCTGTGACACAGGGTATCATTTCCGCTAAAAACCGAACGATCACGAATCAAAATCCAGAAACAGGACAACCTACGAAT
ATTAATGCCATTCAAACAGATGCGGCGATTAATCCTGGGAACTCTGGTGGGCCATTAATTAATATTGCAGGCCAAGTAAT
CGGAATTAACTCTATTAAGATTGCGCGAGCAGCGAGTGGTATCTCTGCTGAGGGTATGGGCTTTTCTATTCCAAGTAACG
ATGTTGTCGATATTATTAATCAACTAGAACAAAACGGACAAGTCATTCGCCCAATGTTAGGTGTGACGATGATTGATTTA
GCGGTCATTAGCCAAGAACAACAAGAAAAAATCTTGAAGTTACCAACAGATATTAAATCTGGCGTAATCATTCGTAGCGT
TCAGGCCGCTTCTCCTGCTGAAGCAGCAGGCTTAAAACAGTATGATGTGATTGTAGGAATTGATGGTAAAGAGATTGAAA
ATGCGACTGACCTTCAAACCATTCTATATACGAAAAAAGTCGGGGACGAGATTGAGGTAACCTACTATCGTGAGCATCAC
AAAAATACCGTGAAAGTTTCCCTTTCACTAGACCGTTCTTCTTTAGAAAAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (312-408)

• Peptidase family M50 (Peptidase_M50) (79-408)

• Trypsin-like peptidase domain (Trypsin_2) (123-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	55.163	88.038	0.486
htrA	Streptococcus gordonii str. Challis substr. CH1	48.628	95.933	0.467
htrA	Streptococcus mitis NCTC 12261	49.081	91.148	0.447
htrA	Streptococcus pneumoniae TIGR4	50.139	86.364	0.433
htrA	Streptococcus pneumoniae D39	50.139	86.364	0.433
htrA	Streptococcus pneumoniae Rx1	50.139	86.364	0.433
htrA	Streptococcus pneumoniae R6	50.139	86.364	0.433