Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   M2905_RS07530 Genome accession   NZ_CP097051
Coordinates   1555625..1556881 (-) Length   418 a.a.
NCBI ID   WP_248856534.1    Uniprot ID   -
Organism   Vagococcus lutrae strain AT19     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1550625..1561881
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2905_RS07510 (M2905_07510) walK 1550807..1552633 (+) 1827 WP_222317028.1 cell wall metabolism sensor histidine kinase WalK -
  M2905_RS07515 (M2905_07515) yycH 1552630..1553934 (+) 1305 WP_126762859.1 two-component system activity regulator YycH -
  M2905_RS07520 (M2905_07520) - 1553934..1554764 (+) 831 WP_248856533.1 two-component system regulatory protein YycI -
  M2905_RS07525 (M2905_07525) - 1554782..1555588 (+) 807 WP_126762855.1 MBL fold metallo-hydrolase -
  M2905_RS07530 (M2905_07530) htrA 1555625..1556881 (-) 1257 WP_248856534.1 trypsin-like peptidase domain-containing protein Regulator
  M2905_RS07535 (M2905_07535) rlmH 1557218..1557697 (+) 480 WP_248856535.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  M2905_RS07540 (M2905_07540) - 1557727..1558740 (+) 1014 WP_248856536.1 hypothetical protein -
  M2905_RS07545 (M2905_07545) - 1558724..1558915 (+) 192 WP_248856537.1 hypothetical protein -
  M2905_RS07550 (M2905_07550) - 1559077..1560033 (+) 957 WP_248855403.1 restriction endonuclease -
  M2905_RS07555 (M2905_07555) yghU 1560279..1561064 (+) 786 WP_248853075.1 glutathione-dependent disulfide-bond oxidoreductase -
  M2905_RS07560 (M2905_07560) - 1561264..1561734 (-) 471 WP_248856538.1 nucleoside deaminase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44297.68 Da        Isoelectric Point: 4.4798

>NTDB_id=686697 M2905_RS07530 WP_248856534.1 1555625..1556881(-) (htrA) [Vagococcus lutrae strain AT19]
MKTYETSTSSPLKRFGTGLLGGLIGGAVAFGLLFNFNQGSDKTSQPLNNHGEATKVEKVAYDVENNTSKAVEKVQGAVVS
VINLQKRQEMADEYGLGGLFGLPQQPEKKSENNQDELETSSEGSGVIYKKDGKNAYVVTNNHVVEGSDALEVLMNDGSKV
SAELVGADAYTDLAVLKISAEGVKDTAEFGDSDVLKIGEPAIAIGSPLGSDYANSVTQGIISAKNRTITNQNPETGQPTN
INAIQTDAAINPGNSGGPLINIAGQVIGINSIKIARAASGISAEGMGFSIPSNDVVDIINQLEQNGQVIRPMLGVTMIDL
AVISQEQQEKILKLPTDIKSGVIIRSVQAASPAEAAGLKQYDVIVGIDGKEIENATDLQTILYTKKVGDEIEVTYYREQH
KNTVKVSLSLDRSSLEKE

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=686697 M2905_RS07530 WP_248856534.1 1555625..1556881(-) (htrA) [Vagococcus lutrae strain AT19]
ATGAAAACATATGAAACATCTACTTCATCCCCTCTTAAACGTTTTGGAACGGGACTTTTAGGCGGACTCATTGGAGGTGC
CGTCGCGTTTGGTCTTTTATTTAATTTCAATCAAGGCAGTGATAAGACATCTCAGCCATTAAACAATCATGGTGAAGCTA
CGAAAGTTGAGAAAGTGGCTTATGATGTGGAAAACAATACTTCTAAAGCCGTGGAGAAAGTACAAGGCGCTGTCGTTTCT
GTCATTAATTTACAAAAACGACAAGAAATGGCGGATGAATATGGACTTGGTGGACTATTCGGTTTACCGCAACAACCCGA
AAAGAAATCAGAAAATAATCAAGACGAGCTCGAAACTTCTAGCGAGGGCAGTGGGGTTATTTACAAAAAAGATGGTAAAA
ACGCCTATGTTGTGACTAATAATCACGTCGTGGAAGGTTCTGATGCTTTAGAAGTTTTAATGAACGACGGTTCAAAAGTA
TCCGCTGAACTAGTTGGTGCCGACGCTTATACCGATTTGGCTGTTTTAAAAATCAGTGCCGAGGGCGTAAAAGATACTGC
TGAATTTGGTGATTCTGATGTTCTAAAAATTGGTGAACCTGCGATTGCGATTGGTTCTCCACTCGGTTCTGATTATGCTA
ACTCTGTGACACAGGGTATCATTTCCGCTAAAAACCGAACGATCACGAATCAAAATCCAGAAACAGGACAACCTACGAAT
ATTAATGCCATTCAAACAGATGCGGCGATTAATCCTGGGAACTCTGGTGGGCCATTAATTAATATTGCCGGCCAAGTCAT
CGGAATTAACTCCATTAAGATTGCGAGAGCAGCGAGTGGTATCTCTGCTGAGGGGATGGGCTTTTCTATTCCGAGTAATG
ATGTTGTCGATATTATTAATCAACTAGAACAAAACGGACAAGTCATTCGCCCAATGTTAGGTGTGACGATGATTGATTTA
GCGGTCATTAGCCAAGAACAACAAGAAAAAATCTTAAAATTACCAACAGATATTAAATCTGGTGTAATCATTCGTAGCGT
TCAGGCCGCTTCTCCTGCTGAAGCAGCAGGCTTAAAACAGTATGATGTGATTGTAGGAATTGATGGTAAAGAGATTGAAA
ATGCGACTGACCTTCAAACCATTCTATATACGAAAAAAGTCGGGGACGAGATTGAGGTAACCTACTATCGCGAACAACAT
AAAAATACCGTGAAAGTTTCCCTCTCATTAGACCGTTCTTCTTTAGAAAAAGAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(123-269)

PDZ domain (PDZ_2)

(312-408)

Peptidase family M50 (Peptidase_M50)

(10-408)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

54.331

91.148

0.495
  htrA Streptococcus gordonii str. Challis substr. CH1

48.379

95.933

0.464
  htrA Streptococcus mitis NCTC 12261

49.081

91.148

0.447
  htrA Streptococcus pneumoniae TIGR4

50.139

86.364

0.433
  htrA Streptococcus pneumoniae D39

50.139

86.364

0.433
  htrA Streptococcus pneumoniae Rx1

50.139

86.364

0.433
  htrA Streptococcus pneumoniae R6

50.139

86.364

0.433