Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   M2919_RS06075 Genome accession   NZ_CP097017
Coordinates   1275030..1276286 (+) Length   418 a.a.
NCBI ID   WP_248848402.1    Uniprot ID   -
Organism   Vagococcus lutrae strain AT46b     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1270030..1281286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2919_RS06050 (M2919_06050) - 1270306..1271403 (-) 1098 WP_248848400.1 aminotransferase class V-fold PLP-dependent enzyme -
  M2919_RS06055 (M2919_06055) - 1271408..1272289 (-) 882 WP_202585106.1 phosphotriesterase family protein -
  M2919_RS06060 (M2919_06060) - 1272308..1273624 (-) 1317 WP_202585107.1 YhfT family protein -
  M2919_RS06065 (M2919_06065) - 1273650..1274012 (-) 363 WP_202585108.1 DUF2620 domain-containing protein -
  M2919_RS06070 (M2919_06070) rlmH 1274214..1274693 (-) 480 WP_248848401.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  M2919_RS06075 (M2919_06075) htrA 1275030..1276286 (+) 1257 WP_248848402.1 S1C family serine protease Regulator
  M2919_RS06080 (M2919_06080) - 1276323..1277129 (-) 807 WP_126762855.1 MBL fold metallo-hydrolase -
  M2919_RS06085 (M2919_06085) - 1277147..1277977 (-) 831 WP_202585780.1 two-component system regulatory protein YycI -
  M2919_RS06090 (M2919_06090) - 1277977..1279281 (-) 1305 WP_202585779.1 YycH family regulatory protein -
  M2919_RS06095 (M2919_06095) walK 1279278..1281104 (-) 1827 WP_248848403.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44379.78 Da        Isoelectric Point: 4.4966

>NTDB_id=686223 M2919_RS06075 WP_248848402.1 1275030..1276286(+) (htrA) [Vagococcus lutrae strain AT46b]
MKTYETSTSSPLKRFGTGLLGGLIGGAVAFGLLFNFNQDSDKTSQPLNNHGEATKVEKVAYDVENNTSKAVEKVQGAVVS
VINLQKRQEMADEYGLGGLFGLPQQPEKKSEDKQDELETSSEGSGVIYKKDGKNAYVVTNNHVVEGSDALEVLMNDGSKV
SAELVGADAYTDLAVLKISAEGVKDTAEFGDSDVLKIGEPAIAIGSPLGSDYANSVTQGIISAKNRTITNQNPETGQPTN
INAIQTDAAINPGNSGGPLINIAGQVIGINSIKIARAASGISAEGMGFSIPSNDVVDIINQLEQNGQVIRPMLGVTMIDL
AVISQEQQEKILKLPTDIKSGVIIRSVQAASPAEAAGLKQYDVIVGIDGKEIENATDLQTILYTKKVGDEIEVTYYREHH
KNTVKVSLSLDRSSLEKE

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=686223 M2919_RS06075 WP_248848402.1 1275030..1276286(+) (htrA) [Vagococcus lutrae strain AT46b]
ATGAAAACATATGAAACATCTACTTCATCCCCTCTTAAACGTTTTGGAACGGGACTTTTAGGCGGACTCATTGGAGGTGC
CGTCGCGTTTGGTCTTTTATTTAATTTCAATCAAGACAGTGATAAGACATCTCAGCCATTAAACAATCATGGTGAAGCTA
CGAAAGTTGAGAAAGTGGCTTATGATGTGGAAAACAATACTTCTAAAGCCGTGGAGAAAGTACAAGGCGCTGTCGTTTCT
GTTATTAATTTACAAAAACGACAAGAAATGGCGGATGAATATGGACTTGGTGGACTATTCGGTTTACCGCAACAACCCGA
AAAGAAATCAGAAGATAAACAAGACGAGCTCGAAACTTCTAGCGAGGGCAGTGGGGTTATTTATAAAAAAGATGGTAAAA
ACGCCTATGTTGTGACTAATAATCACGTCGTGGAAGGTTCTGATGCTTTAGAAGTTTTAATGAACGACGGTTCAAAAGTG
TCCGCTGAACTAGTTGGTGCCGACGCTTATACTGATTTGGCTGTTTTAAAAATCAGTGCCGAGGGCGTAAAAGATACTGC
TGAATTTGGTGATTCTGATGTTCTAAAAATTGGTGAACCTGCGATTGCGATTGGTTCTCCACTCGGTTCTGATTATGCTA
ACTCTGTGACACAGGGTATCATTTCCGCTAAAAACCGAACAATCACGAATCAAAATCCAGAAACAGGACAACCTACGAAT
ATTAATGCCATTCAAACAGATGCGGCGATTAATCCTGGGAACTCTGGTGGGCCATTAATTAATATTGCGGGCCAAGTAAT
CGGAATTAACTCCATTAAGATTGCACGAGCAGCGAGTGGTATCTCTGCTGAGGGTATGGGCTTCTCTATTCCAAGTAATG
ATGTTGTCGATATTATTAATCAACTAGAACAAAACGGACAAGTCATTCGCCCAATGTTAGGTGTGACGATGATTGATTTA
GCGGTCATTAGCCAAGAACAACAAGAAAAAATCTTAAAATTGCCAACAGATATTAAATCTGGTGTAATCATTCGTAGCGT
TCAGGCCGCTTCTCCTGCTGAAGCAGCAGGCTTAAAACAGTATGATGTGATTGTAGGAATTGATGGTAAAGAGATTGAAA
ATGCGACTGACCTTCAAACCATTCTATATACGAAAAAAGTCGGGGACGAGATTGAGGTAACCTACTATCGTGAGCATCAC
AAAAATACCGTGAAAGTTTCCCTTTCACTAGACCGTTCTTCTTTAGAAAAAGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(312-408)

Peptidase family M50 (Peptidase_M50)

(79-408)

Trypsin-like peptidase domain (Trypsin_2)

(123-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.163

88.038

0.486
  htrA Streptococcus gordonii str. Challis substr. CH1

48.13

95.933

0.462
  htrA Streptococcus mitis NCTC 12261

49.081

91.148

0.447
  htrA Streptococcus pneumoniae TIGR4

50.139

86.364

0.433
  htrA Streptococcus pneumoniae D39

50.139

86.364

0.433
  htrA Streptococcus pneumoniae Rx1

50.139

86.364

0.433
  htrA Streptococcus pneumoniae R6

50.139

86.364

0.433