Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SNAG_RS07690 Genome accession   NZ_AP017652
Coordinates   1481718..1483619 (-) Length   633 a.a.
NCBI ID   WP_096408140.1    Uniprot ID   A0A1E1GCA0
Organism   Streptococcus sp. NPS 308     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1476718..1488619
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SNAG_RS07665 (SNAG_1500) - 1476849..1477814 (+) 966 WP_096408132.1 LacI family DNA-binding transcriptional regulator -
  SNAG_RS07670 (SNAG_1501) - 1477850..1479124 (-) 1275 WP_096408135.1 hydroxymethylglutaryl-CoA reductase, degradative -
  SNAG_RS07675 (SNAG_1502) - 1479124..1480296 (-) 1173 WP_096408887.1 hydroxymethylglutaryl-CoA synthase -
  SNAG_RS07680 (SNAG_1503) - 1480415..1480870 (-) 456 WP_000176905.1 threonine/serine exporter family protein -
  SNAG_RS07685 (SNAG_1504) - 1480872..1481630 (-) 759 WP_096408137.1 threonine/serine exporter family protein -
  SNAG_RS07690 (SNAG_1505) stkP 1481718..1483619 (-) 1902 WP_096408140.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SNAG_RS07695 (SNAG_1506) - 1483616..1484356 (-) 741 WP_096408142.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SNAG_RS07700 (SNAG_1507) rsmB 1484372..1485685 (-) 1314 WP_172842403.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SNAG_RS07705 (SNAG_1508) fmt 1485678..1486613 (-) 936 WP_096408147.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69019.36 Da        Isoelectric Point: 9.1469

>NTDB_id=68361 SNAG_RS07690 WP_096408140.1 1481718..1483619(-) (stkP) [Streptococcus sp. NPS 308]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYQSVSEMYVDLSSSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KATQPVAEPAPAPKPAKKRKFKARYMILLASLLLVVASLIWILSRTPATIAIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLVVSSGKQSFQLSNYVGRKYTEVVAELKEKKVPENLIQMEEEESSESEPGTI
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPNYIGSSLEFTKNNLTQIVGVKEANIEVIEVSTAPEGTAEGTVVSQTP
KAGEKVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSTTTPNQGNQQGNQQGNNPPTNQPNNEGNRESSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=68361 SNAG_RS07690 WP_096408140.1 1481718..1483619(-) (stkP) [Streptococcus sp. NPS 308]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACAGACCCTATTG
CTGTGGCACGTTTCCAACGTGAAGCGAGAGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGATGGTCAACAGTACCTAGCTATGGAATACGTAGCAGGTCTTGACCTCAAGCGTTATATCAAAGAACACTATCC
TCTTTCAAACGAAGAAGCAGTTCGGATTATGGGACAAATCCTCTTAGCAATGCGCTTAGCCCATACTCGAGGAATCGTTC
ACCGGGATTTGAAACCTCAAAATATCCTACTGACCCCTGATGGCACAGCCAAGGTCACGGACTTTGGAATTGCAGTAGCC
TTTGCGGAGACCAGTCTGACTCAGACAAACTCGATGCTAGGCTCCGTTCATTACTTGTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACTTTCCAGAGCGATATCTATGCAATGGGGATTATCTTCTATGAGATGCTAACTGGTCACATTCCTTACGATG
GGGATAGTGCAGTTACGATTGCTCTCCAGCATTTCCAGAAGCCTCTTCCATCAGTCATTGCTGAAAACCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCAACTGCCAAGAAATTGACGGATCGCTATCAGTCTGTTTCGGAAATGTATGT
AGATTTGTCGAGTAGTTTGTCCTACAATCGCCGAAATGAACCAAAATTGGTCTTTGATGATGCCAGCAAGGCAGATACCA
AGACCTTGCCTAAAGTTCCACAAAGTACACTGACGTCTATTCCTAAAGCGCCTGCGCAGGAAGAGCGTCCTCAGCCAAAG
AAAGCTACTCAACCAGTCGCTGAGCCAGCACCTGCACCAAAGCCAGCTAAAAAACGGAAGTTTAAAGCTCGCTATATGAT
TCTTTTAGCTAGCCTTCTATTGGTTGTAGCCTCTTTAATCTGGATTTTGTCAAGAACACCTGCAACGATTGCTATTCCTG
ACGTGGCTGGACAAACTGTTGCAGAAGCCAAAGAAGCACTCAAAAAATCCAAGTTTGAAGCTGGCGAAGAGAAATCGGAG
GCTAGTGATACAGTAGCAGAAGGACGCGTTATTCGAACCGATCCAGAAGCTGGTAGTGGCCGAAAAGAAGGAACCAAGGT
CAATTTGGTTGTCTCTTCTGGGAAGCAATCTTTCCAATTGAGCAATTACGTCGGACGCAAGTATACGGAAGTCGTGGCTG
AACTCAAGGAGAAAAAGGTGCCAGAAAATCTAATCCAGATGGAAGAAGAAGAATCCAGCGAAAGCGAACCCGGAACCATC
CTCAGACAAACCCCTGCTTCGGGTTCGACTTATGATCTCTCAAAAGCCACTACGATTACCTTAACAGTGGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACATCGGTTCAAGTCTCGAGTTTACAAAGAATAACTTGACTCAGATTGTCGGAGTAA
AAGAGGCTAATATTGAGGTTATTGAAGTATCGACTGCTCCTGAAGGAACAGCAGAAGGAACTGTTGTAAGTCAAACACCA
AAAGCTGGTGAAAAGGTTGACCTTGCTAGCACGCGTATCAAACTTTCCATCTACAAACCAAAAACACCACCATCAACTTC
ATCCTCTAATCCTGCCCAACGTGGGAACCAAGGTTCTACAACAACACCAAATCAAGGGAACCAGCAAGGAAATCAACAAG
GTAATAATCCTCCAACGAATCAACCAAACAATGAAGGAAACCGCGAAAGTTCTCGAGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E1GCA0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.84

92.575

0.73
  stkP Streptococcus pneumoniae D39

78.498

92.575

0.727
  stkP Streptococcus pneumoniae R6

78.498

92.575

0.727
  stkP Streptococcus pneumoniae Rx1

78.328

92.575

0.725
  pknB Streptococcus mutans UA159

56.153

91.153

0.512
  stkP/pknB Streptococcus salivarius strain HSISS4

53.48

93.049

0.498

Multiple sequence alignment