Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SNAG_RS03690 Genome accession   NZ_AP017652
Coordinates   695164..695904 (+) Length   246 a.a.
NCBI ID   WP_096406668.1    Uniprot ID   A0A1E1G9Y8
Organism   Streptococcus sp. NPS 308     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 690164..700904
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SNAG_RS03675 (SNAG_0724) - 692287..693003 (+) 717 WP_096406663.1 LicD family protein -
  SNAG_RS03680 (SNAG_0725) - 693193..693513 (+) 321 Protein_661 MBL fold metallo-hydrolase -
  SNAG_RS03685 (SNAG_0726) - 693563..695041 (-) 1479 WP_096406665.1 oligosaccharide flippase family protein -
  SNAG_RS03690 (SNAG_0727) mecA 695164..695904 (+) 741 WP_096406668.1 adaptor protein MecA Regulator
  SNAG_RS03695 (SNAG_0728) - 696052..697338 (+) 1287 WP_096406670.1 homoserine dehydrogenase -
  SNAG_RS03700 (SNAG_0729) thrB 697340..698209 (+) 870 WP_096406672.1 homoserine kinase -
  SNAG_RS03710 (SNAG_0730) msrB 698513..699451 (+) 939 WP_096406677.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28541.35 Da        Isoelectric Point: 4.1097

>NTDB_id=68344 SNAG_RS03690 WP_096406668.1 695164..695904(+) (mecA) [Streptococcus sp. NPS 308]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLIPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQVDKETESKKEPYIYYILRFS
SLGDLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=68344 SNAG_RS03690 WP_096406668.1 695164..695904(+) (mecA) [Streptococcus sp. NPS 308]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGGATGGAGAT
TGCAGACTTTCTCATTCCTCAGGAAAAAACAGAAGAGTTTTTCTATGCTATTTTAGATGAATTAGAGATGCCAGACAATT
TCTTGGACAGTGGCATGCTGAGTTTTCGTGTAACACCAAAACCAGATAAGGTCGATGTCTTTGTGACCAAGTCTAAGATT
GACCAAAACCTTGATTTTGAAGATTTGGCGGACCTACCTGATATGGAAGAGTTGGCCCAAATGTCGCCAGATGAATTTCT
CAAGACGCTAGAAAAGAGTATCGCAGATAAGACCAAGGACGATATTGAGGCCATCCAATCTCTAGAACAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGTAGACAAGGAGACGGAGAGCAAGAAAGAACCTTATATCTACTATATCCTGCGCTTTTCA
AGCCTTGGTGACTTAGTTGCTTTTGCAAAGACGGTTAACTATCAGATGGAAACATCTGAACTCTATAAGATGAATGGGCA
CTACTATTTGACAATCTTAGTCGATGTAGAAAATCATCCTAGTCCATATCCGGCCTGGCTCTTGGCTCGTATGCGTGAAT
TTGCAGACGATAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATATTGATTAACCATGATGCAGTTCTCGGT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E1G9Y8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

89.344

99.187

0.886
  mecA Streptococcus pneumoniae D39

89.344

99.187

0.886
  mecA Streptococcus pneumoniae R6

89.344

99.187

0.886
  mecA Streptococcus pneumoniae TIGR4

88.934

99.187

0.882
  mecA Streptococcus thermophilus LMD-9

48.016

100

0.492
  mecA Streptococcus thermophilus LMG 18311

47.619

100

0.488
  mecA Streptococcus mutans UA159

48.77

99.187

0.484

Multiple sequence alignment