Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   OHM47_RS01260 Genome accession   NZ_CP109939
Coordinates   220185..221840 (+) Length   551 a.a.
NCBI ID   WP_249547177.1    Uniprot ID   -
Organism   Streptococcus suis strain ID36054     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 215185..226840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHM47_RS01230 (OHM47_01230) - 216021..216866 (-) 846 WP_024394846.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
  OHM47_RS01235 (OHM47_01235) - 216863..217453 (-) 591 WP_002935109.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
  OHM47_RS01240 (OHM47_01240) - 217736..217894 (+) 159 Protein_211 putative cross-wall-targeting lipoprotein signal domain-containing proteiin -
  OHM47_RS01245 (OHM47_01245) - 218085..219401 (+) 1317 WP_002935107.1 glycosyltransferase family 2 protein -
  OHM47_RS01250 (OHM47_01250) - 219430..219702 (+) 273 WP_002935103.1 DUF3884 family protein -
  OHM47_RS01255 (OHM47_01255) - 219791..219982 (+) 192 WP_002935101.1 hypothetical protein -
  OHM47_RS01260 (OHM47_01260) comA 220185..221840 (+) 1656 WP_249547177.1 peptide cleavage/export ABC transporter Regulator
  OHM47_RS01265 (OHM47_01265) - 221944..222948 (-) 1005 WP_002935211.1 IS5 family transposase -
  OHM47_RS01270 (OHM47_01270) comA 223043..223531 (+) 489 WP_249547176.1 ATP-binding cassette domain-containing protein Regulator
  OHM47_RS01275 (OHM47_01275) - 223553..223708 (+) 156 WP_000794567.1 hypothetical protein -
  OHM47_RS01280 (OHM47_01280) - 224168..225037 (+) 870 WP_226313481.1 GHKL domain-containing protein -
  OHM47_RS01285 (OHM47_01285) comE/comE2 225052..225801 (+) 750 WP_024394858.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator

Sequence

Protein


Download         Length: 551 a.a.        Molecular weight: 62952.95 Da        Isoelectric Point: 9.2118

>NTDB_id=682337 OHM47_RS01260 WP_249547177.1 220185..221840(+) (comA) [Streptococcus suis strain ID36054]
MKFSKRHYRAQVDSKDCGVAALAMVLEYYNSHYSLAELREMLGTTENGTTAFSIVSVANELGFDTEAIYADISLFDIEDI
KFPFIVHINKNNKFYHYYVIIGSDKKYIYIADPDPLIKLSKLTKEQFLAEWRGITILLKPNHEYKIKRKKTSFPSLFTLL
FNQKKLIFLIILLTLAVNFINIIGSYYLKRVIDSYIPKGELDFLNLMSISLIVIYLMQQFFVFGQGVLITVLSQILSKNI
MLSYIAHLFKLPLSFFATRRTGDIVSRFSDANIIIEVLSSIILSVILDVSIVTGVSIVLFLQSSYLFFIIIIAFPIYALV
IFLFMKPFRHSKTSVMEAGASLSSVLIEDINGIETIKSLTSEVDRYKKIKDEFSNYYKKITFYSRMELFQDVLKNFTQLL
FNVLILWQGAILVIEGKISLGSLITFNTLELYFLNSLENIINLQPKFQSASVAYNRLEEIYSVQSEFQDKFFITNFKLNS
SKIVISNLTYKYGYNQPLLKDINLVIEEGCKIAFVGLSGSGKTTLAKMLVNFMPPTYGSIEFGGININGHL

Nucleotide


Download         Length: 1656 bp        

>NTDB_id=682337 OHM47_RS01260 WP_249547177.1 220185..221840(+) (comA) [Streptococcus suis strain ID36054]
ATGAAATTTTCGAAACGTCATTATCGTGCTCAAGTTGATTCAAAAGATTGTGGAGTAGCTGCTTTGGCCATGGTGTTAGA
ATACTATAATTCACATTATTCTTTAGCAGAACTTAGAGAAATGTTAGGTACAACTGAAAATGGGACTACTGCATTTAGTA
TAGTTTCTGTGGCAAATGAATTAGGGTTCGATACTGAAGCTATTTATGCAGATATTTCTTTATTTGACATAGAGGATATA
AAATTTCCATTTATTGTACATATAAATAAGAATAATAAATTTTATCATTACTATGTTATTATTGGCAGTGATAAAAAATA
TATTTATATAGCTGATCCTGATCCTCTGATAAAATTATCTAAACTAACTAAAGAACAGTTTCTTGCAGAATGGAGAGGGA
TAACTATATTATTAAAACCAAACCATGAGTACAAAATTAAAAGAAAGAAGACAAGTTTTCCTTCTTTATTTACTTTACTG
TTTAATCAAAAGAAATTAATTTTTTTAATTATATTATTAACTTTAGCAGTAAACTTTATCAATATAATTGGTTCATACTA
TTTAAAGAGAGTAATTGATTCTTATATTCCTAAAGGGGAGCTGGATTTTCTTAATCTAATGTCAATAAGCCTAATTGTTA
TTTATCTTATGCAACAGTTTTTTGTATTTGGTCAAGGGGTATTGATAACAGTTCTAAGTCAAATACTTTCAAAAAATATA
ATGCTGTCATATATTGCTCACCTTTTTAAACTTCCTCTATCTTTTTTTGCAACAAGAAGAACTGGCGATATTGTCTCTAG
ATTTTCAGATGCTAATATCATAATTGAAGTATTATCTAGTATAATTTTATCTGTAATACTAGATGTGTCAATAGTTACTG
GAGTATCAATTGTACTTTTTTTGCAAAGTAGTTATTTATTTTTTATTATAATTATTGCGTTTCCAATTTATGCTTTAGTA
ATTTTTTTATTCATGAAACCATTTAGACATAGTAAAACTAGTGTAATGGAAGCAGGAGCTTCACTTTCCTCAGTTCTTAT
AGAAGATATAAATGGAATAGAGACAATAAAATCTCTTACTAGTGAGGTTGATCGCTATAAAAAAATAAAAGACGAATTTA
GTAATTATTATAAAAAAATTACTTTTTATAGTAGAATGGAGTTGTTTCAAGATGTGTTAAAAAATTTTACTCAATTGTTG
TTTAATGTATTAATTTTATGGCAAGGTGCTATTTTAGTAATTGAAGGAAAAATATCATTGGGATCTTTGATAACCTTTAA
TACTTTAGAACTTTATTTTCTGAATTCACTGGAGAACATTATTAATTTACAACCTAAATTTCAATCAGCAAGTGTTGCGT
ATAATAGATTAGAAGAAATCTATTCGGTTCAATCAGAATTTCAGGATAAGTTCTTCATAACAAATTTTAAATTGAATTCT
AGTAAGATAGTAATTTCAAATTTAACCTACAAATATGGCTATAACCAGCCTCTATTAAAAGATATTAATTTAGTTATCGA
GGAAGGTTGTAAAATAGCATTTGTTGGTCTTTCTGGTTCAGGGAAAACAACTCTAGCAAAAATGTTAGTTAATTTTATGC
CTCCTACCTATGGAAGTATTGAATTTGGAGGAATTAATATTAATGGGCACCTCTAA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(499-547)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(167-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

55.738

99.637

0.555
  comA Streptococcus mitis NCTC 12261

55.556

99.637

0.554
  comA Streptococcus mitis SK321

55.373

99.637

0.552
  comA Streptococcus pneumoniae R6

55.009

99.637

0.548
  comA Streptococcus pneumoniae Rx1

55.009

99.637

0.548
  comA Streptococcus pneumoniae D39

55.009

99.637

0.548
  comA Streptococcus pneumoniae TIGR4

54.827

99.637

0.546
  comA/nlmT Streptococcus mutans UA159

47.89

98.911

0.474