Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   NALG_RS06580 Genome accession   NZ_AP017373
Coordinates   1336624..1337841 (-) Length   405 a.a.
NCBI ID   WP_017369969.1    Uniprot ID   A0A9Q9D6R4
Organism   Lactococcus formosensis strain 122061     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1331624..1342841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NALG_RS06550 (NALG_1314) - 1331919..1332668 (+) 750 WP_096368974.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  NALG_RS06560 (NALG_1315) - 1332828..1333877 (+) 1050 WP_017369973.1 BMP family protein -
  NALG_RS06565 (NALG_1316) - 1333907..1334131 (-) 225 WP_017369972.1 DUF1797 family protein -
  NALG_RS06570 (NALG_1317) - 1334182..1335516 (-) 1335 WP_096368975.1 glycosyltransferase family 4 protein -
  NALG_RS06575 (NALG_1318) - 1335529..1336527 (-) 999 WP_096368976.1 glycosyltransferase family 4 protein -
  NALG_RS06580 (NALG_1319) htrA 1336624..1337841 (-) 1218 WP_017369969.1 trypsin-like peptidase domain-containing protein Regulator
  NALG_RS06585 (NALG_1320) rlmH 1338145..1338624 (+) 480 WP_096368977.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  NALG_RS06590 (NALG_1321) - 1338621..1339268 (+) 648 WP_096368978.1 DNA alkylation repair protein -
  NALG_RS06595 (NALG_1322) yajC 1339343..1339675 (+) 333 WP_017369966.1 preprotein translocase subunit YajC -
  NALG_RS06600 (NALG_1323) - 1339874..1340611 (+) 738 WP_096368979.1 isoprenyl transferase -
  NALG_RS06605 (NALG_1324) - 1340608..1341402 (+) 795 WP_096368980.1 phosphatidate cytidylyltransferase -
  NALG_RS06610 (NALG_1325) eeP 1341579..1342826 (+) 1248 WP_096368981.1 RIP metalloprotease RseP Regulator

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41850.60 Da        Isoelectric Point: 4.6948

>NTDB_id=67824 NALG_RS06580 WP_017369969.1 1336624..1337841(-) (htrA) [Lactococcus formosensis strain 122061]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNESNSPQLSGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVQETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSSSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
DVTNGVAVAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATTNIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=67824 NALG_RS06580 WP_017369969.1 1336624..1337841(-) (htrA) [Lactococcus formosensis strain 122061]
ATGGCAAAAAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGGGGTAGTGCTATCTA
CCAAAATATGACTAACACGCCGTCATCTAATAATACTTCGGACAATTCTGTAAGTACAGTTAACGTACAAGTCAATACAG
ATACAACCAAAGCAATCAAGAAAATTTCAAACACTGTTGTTTCCGTACTTAATTACCAAAAATCGTCTTCAAGCAACGAC
TTTGAAAAGATTTTCGGCGGAGGCGACACAAGCAGCAATGAGAGTAACTCACCACAGCTATCTGGAGAAGGTTCTGGGGT
TATCTATAAAAAGGACGGCAATACCGCATACATCGTAACCAACTATCACGTTATTGAAGGTGCGTCTTCCTTAGAAGTTC
TCATGGCTGGTGGTCAAAAAGTAACTGCCGAAGTTGTTGGTTCCGATGCTTATTCGGATTTAGCTGTCCTCAAAATTGAT
GCCAAGTATGTCCAAGAAACCGCAACGTTCGGCAACTCTGACAAACTTACTGTTGGTGAACCTGCTATCGCCGTTGGTTC
TCCTCTTGGAAGTGAGTATGCTAACTCAGCAACAGAAGGTATTGTTTCTAGTCTTAATCGCAATGTTACATTGCAAAACA
GCCAAGGCCAAACCATTAATGTTAATGCTATTCAAACAGATGCAGCAATAAACCCCGGGAACTCTGGCGGTGCACTCATC
AATATTCAAGGACAAGTCATCGGGATCACCTCAAGTAAAATTACCTCAACACCAAGTGGAACAAGCAGCAGTGGTGTCTC
TGTAGAAGGTATGGGGTTTGCGATTCCAGCCAATGATGTCGTCAATATTATCAATAAATTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTGGGTGTGCAAATGGTTAACCTATCAAGTCTTTCACAAAATATGTTGGCTTCACTTAACCTTCCTGAA
GACGTGACTAATGGTGTTGCTGTCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGCGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTGTTAACCTTCAAAGCACACTTTATAAATCTTCAATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTACAAATATCAAGTTAGATAAAACAAGTAGTGATATCAAT
TTTGACAAGCAAAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

Peptidase family M50 (Peptidase_M50)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.878

93.333

0.531
  htrA Streptococcus mitis NCTC 12261

53.634

98.519

0.528
  htrA Streptococcus pneumoniae Rx1

53.383

98.519

0.526
  htrA Streptococcus pneumoniae D39

53.383

98.519

0.526
  htrA Streptococcus pneumoniae R6

53.383

98.519

0.526
  htrA Streptococcus pneumoniae TIGR4

53.383

98.519

0.526
  htrA Streptococcus gordonii str. Challis substr. CH1

54.22

96.543

0.523

Multiple sequence alignment