Detailed information NTG0676637

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: MU539_RS10865
• Genome accession: NZ_CP095384
• Coordinates: 2325117..2327309 (-)
• Length: 730 a.a.
• NCBI ID: WP_033571746.1
• Uniprot ID: -
• Organism: Lacticaseibacillus rhamnosus strain VHProbi M14
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2320117..2332309

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MU539_RS10840 (MU539_10815)	-	2320336..2321418 (+)	1083	WP_080729463.1	aldo/keto reductase	-
MU539_RS10845 (MU539_10820)	-	2321444..2321647 (-)	204	WP_235717744.1	hypothetical protein	-
MU539_RS10850 (MU539_10825)	-	2321719..2323074 (-)	1356	WP_033571744.1	threonine/serine exporter ThrE family protein	-
MU539_RS10855 (MU539_10830)	-	2323257..2323664 (-)	408	WP_050512823.1	hypothetical protein	-
MU539_RS10860 (MU539_10835)	-	2323725..2325104 (-)	1380	WP_257585649.1	bacteriocin secretion accessory protein	-
MU539_RS10865 (MU539_10840)	comA	2325117..2327309 (-)	2193	WP_033571746.1	peptide cleavage/export ABC transporter	Regulator
MU539_RS13675	-	2327585..2327707 (-)	123	WP_371823836.1	bacteriocin-like peptide, LSEI_2386 family	-
MU539_RS10870 (MU539_10845)	-	2328170..2329219 (+)	1050	WP_235717746.1	GHKL domain-containing protein	-
MU539_RS10875 (MU539_10850)	-	2329224..2330000 (+)	777	WP_033571748.1	response regulator transcription factor	-
MU539_RS10880 (MU539_10855)	-	2330120..2330380 (-)	261	WP_033571749.1	hypothetical protein	-
MU539_RS10885 (MU539_10860)	-	2331353..2331598 (-)	246	WP_033571750.1	hypothetical protein	-
MU539_RS10890 (MU539_10865)	-	2331845..2332144 (-)	300	WP_033571751.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81567.88 Da
• Isoelectric Point: 7.2454

>NTDB_id=676637 MU539_RS10865 WP_033571746.1 2325117..2327309(-) (comA) [Lacticaseibacillus rhamnosus strain VHProbi M14]
MFKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSLAHLRELAKTNQDGTTALGIVRAAEALAFETKPVQA
DMQLFDLEDVPYPFIAHVLKRGELLHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKED
KGSLFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGLLVAYLLQAVLIYGQNFLM
AVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFADANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLV
SLIAVPCYLVIVFAFQRPFDRLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQL
QQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKLQMARVANNRLNEVYLVESEFKE
QRHLTERHLIEGPLRVRNVSFKYGFGQDVLKNVNLEVPENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPV
KDINLTTLRQYIEYVPQDPFIFSGTVLENLTLGSRSDVSEQDLTQACLAAEIAADIANLPQQWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGKIVEQGDHATLLAQ
DGYYARLVHE

Nucleotide

• Length: 2193 bp

>NTDB_id=676637 MU539_RS10865 WP_033571746.1 2325117..2327309(-) (comA) [Lacticaseibacillus rhamnosus strain VHProbi M14]
ATGTTTAAATACACCCCAAAACTAGGCCAGATCACCTACTACAAACGCTTCTACACCGCACAAGTTGACGAGCGTGACTG
TGGTGTAGCTGCGTTAAACATGCTGCTTAAATACAATGGTTCGGACTATTCGTTAGCCCACTTGCGCGAGTTAGCGAAGA
CAAATCAGGATGGCACGACTGCTTTGGGAATCGTTCGGGCGGCTGAAGCACTAGCGTTTGAGACGAAACCGGTGCAGGCG
GATATGCAGTTGTTTGATCTTGAGGATGTGCCTTATCCGTTTATTGCCCATGTGCTGAAGCGTGGTGAATTGCTTCATTA
CTATGTTGTTTTTAAGGCAACGCGCACGAGTATTCTGATTGGGGATCCTGACCCGTCAGTGCGCATGACCTGGCTTTCGC
GAGAGGTGTTTGAAAAAGAATGGTCGGGTGTGGCCATCTTTATTGCCCCGGCGCCGCAGTATCAGCCGCGTAAGGAGGAC
AAAGGCAGTTTGTTTGCGTTTGTACCCATGCTTGCTAAGCAAAAAGGTATTATCGCGAACATTATTCTGGCCGCGGTATT
GATTACGGTCATTAGTATCGTTGGGTCGTATTTTTTGCAGTCTATTATTGATACGTATATCCCCAATGCCATGCGGACGA
CGATGGGGATGATTGCTAGTGGCCTTTTGGTGGCTTACTTGCTGCAAGCTGTGTTGATTTATGGCCAGAATTTTTTGATG
GCGGTGTTGGGGCAGCGGCTTGCGATTGACGTCATTTTAGGGTATGTGCGCCATTTATATGAATTGCCGATGTCGTTTTT
TTCAACTCGGCGGACCGGAGAGATTGTGTCGCGGTTTGCGGATGCCAATAAAATTATTGACGCGCTGGCCAATACGATTA
TGACGTTATTTTTGGATGTCTGGATTGTCCTAATATTAGGCATTGTTCTAGGGATCCAAAATGGGACTTTGTTTTTAGTG
TCATTGATTGCCGTGCCGTGTTATTTGGTGATTGTTTTTGCATTTCAGCGGCCGTTTGATCGGTTGAATCAAGAGACGAT
GGAAAGTAACGCAATCTTGAGCTCATCGATTATTGAAGATTTGAATGGCATTGAAACCATCAAGTCCCTGACCGGCGAAC
GAGTTAGCTATGAACGGGTTGATCGGGAATTTCTAACCTATTTGAAGAAGTCGTTTAGTTACACCAAGGCAGATCAGTTA
CAGCAAGCGATTAAAGGTCTGTTGAAGCTGGCGTTGAACGTTGTGGTGTTGTGGATTGGGGCAAGTTTGGTGATTGCCAA
TCGGATGAGTTTGGGGCAGATGCTGACCTTTAATGCGCTGCTGTCATACTTTACGAATCCGCTTGAAAGCATCATCAACC
TACAGCCAAAGTTACAAATGGCGCGGGTTGCTAACAATCGCTTGAATGAAGTTTATCTGGTCGAATCGGAATTCAAAGAA
CAGCGGCACTTGACGGAGCGGCATTTAATCGAAGGCCCGTTACGCGTTCGGAATGTCTCGTTTAAATATGGTTTTGGCCA
AGATGTGTTGAAAAACGTCAACCTTGAAGTGCCGGAAAATGCTAAATATACCATTGTCGGCATGAGCGGTTCTGGTAAGT
CGACATTAGCAAAATTATTAGTTGGCTTTTACCCGGTTGATGCCGATAAAGGAACCATCACGTTTAATGGCATTCCGGTC
AAAGACATTAACCTGACAACATTACGGCAATATATTGAATATGTACCTCAGGATCCGTTTATTTTTTCGGGCACGGTGTT
GGAGAATTTGACGTTAGGTAGCCGTTCGGATGTTTCGGAACAAGACTTGACGCAGGCGTGTTTGGCTGCGGAAATTGCCG
CAGACATCGCAAACTTACCGCAGCAGTGGCAGACCAAATTGTCAGAAAGCGGCAGCATTTTGTCAGGCGGTCAGAAGCAG
CGGCTGGCGATTGCACGAGCCTTGTTATCACCGGCAAAAGTACTGATTTTTGACGAATCGACCAGCAGTCTGGATACCAT
TACGGAGCGAAAGATTGTCGATCGCTTGCTGGCAATGACGGATCGGACCATTATTTTTGTTGCCCATCGCTTAACCATTG
CGGCTAAAACCGAACAAATTGTGGTGATGGATCATGGCAAAATTGTGGAACAAGGTGACCATGCAACGTTGTTAGCCCAA
GATGGTTATTATGCGCGCTTGGTTCATGAGTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (18-152)

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae D39	58.322	97.945	0.571
comA	Streptococcus pneumoniae R6	58.322	97.945	0.571
comA	Streptococcus pneumoniae Rx1	58.322	97.945	0.571
comA	Streptococcus pneumoniae TIGR4	57.902	97.945	0.567
comA	Streptococcus mitis NCTC 12261	57.902	97.945	0.567
comA	Streptococcus mitis SK321	57.762	97.945	0.566
comA	Streptococcus gordonii str. Challis substr. CH1	56.606	98.493	0.558
comA/nlmT	Streptococcus mutans UA159	53.825	98.493	0.53