Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   MUU77_RS04460 Genome accession   NZ_CP095187
Coordinates   976955..978355 (-) Length   466 a.a.
NCBI ID   WP_245092037.1    Uniprot ID   -
Organism   Pseudoxanthomonas sp. F37     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 960408..975976 976955..978355 flank 979


Gene organization within MGE regions


Location: 960408..978355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUU77_RS04390 (MUU77_04390) - 960801..961226 (+) 426 WP_245092010.1 transposase -
  MUU77_RS04395 (MUU77_04395) coaE 961650..962267 (-) 618 WP_245092012.1 dephospho-CoA kinase -
  MUU77_RS04400 (MUU77_04400) pilD 962301..963164 (-) 864 WP_187573334.1 A24 family peptidase Machinery gene
  MUU77_RS04405 (MUU77_04405) pilC 963174..964430 (-) 1257 WP_245094214.1 type II secretion system F family protein Machinery gene
  MUU77_RS04410 (MUU77_04410) pilB 964728..966470 (-) 1743 WP_245092015.1 type IV-A pilus assembly ATPase PilB Machinery gene
  MUU77_RS04415 (MUU77_04415) - 966685..967533 (+) 849 WP_245092019.1 glycosyltransferase family 2 protein -
  MUU77_RS04420 (MUU77_04420) - 967548..968777 (+) 1230 WP_245092023.1 glycosyltransferase family 4 protein -
  MUU77_RS04425 (MUU77_04425) - 968817..970007 (+) 1191 WP_245092025.1 oligosaccharide flippase family protein -
  MUU77_RS04430 (MUU77_04430) - 969988..971118 (-) 1131 WP_245092027.1 glycosyltransferase -
  MUU77_RS04435 (MUU77_04435) - 971125..971994 (-) 870 WP_245092029.1 FkbM family methyltransferase -
  MUU77_RS04440 (MUU77_04440) - 971991..972776 (-) 786 WP_245092031.1 class I SAM-dependent methyltransferase -
  MUU77_RS04445 (MUU77_04445) - 972879..973973 (+) 1095 WP_245092033.1 glycosyltransferase family 4 protein -
  MUU77_RS04450 (MUU77_04450) - 974030..975964 (-) 1935 WP_245092035.1 hypothetical protein -
  MUU77_RS04455 (MUU77_04455) pilA2 976084..976497 (-) 414 WP_280640360.1 pilin Machinery gene
  MUU77_RS04460 (MUU77_04460) pilR 976955..978355 (-) 1401 WP_245092037.1 sigma-54 dependent transcriptional regulator Regulator

Sequence

Protein


Download         Length: 466 a.a.        Molecular weight: 50544.81 Da        Isoelectric Point: 5.4039

>NTDB_id=676034 MUU77_RS04460 WP_245092037.1 976955..978355(-) (pilR) [Pseudoxanthomonas sp. F37]
MNQSRSALIVDDERDIRELLTLTLGRMGLRIDTAANLGEARELLARNTYDLCFTDMRLPDGNGIDLVGEIARNYPDTPVA
MITAFGNIELAVEALKAGAFDFVSKPVDLAVLRGLVKHALELNNTERAPPPPPPPEQASRLLGSSAAMDALRETIGKVAR
SQAPVYIMGESGTGKELVARTIHEQGARASGPFVPVNCGAIPAELMESEFFGHKKGSFTGAHADKQGLFQAANGGTLFLD
EVAELPLPMQVKLLRAIQEKAVRPVGASGEVQVDVRILSATHKDLGELAADGRFRHDLYYRINVIELRVPPLRERTGDLA
QLTTAILERLAAQHGRMAPSVSPEAMEALGRYPFPGNVRELENILERALAMSEGHSIEIDDLYLPQAPAGRKFGGDFSPG
EVVRDAPGAVDVDPAAGALPDYIEQLERAAIQKALEENRWNKTKAAAQLGITFRALRYKLKKLGME

Nucleotide


Download         Length: 1401 bp        

>NTDB_id=676034 MUU77_RS04460 WP_245092037.1 976955..978355(-) (pilR) [Pseudoxanthomonas sp. F37]
ATGAATCAAAGCCGTAGCGCCCTGATCGTCGACGACGAACGCGACATCCGAGAACTGCTGACGCTGACGCTGGGCCGCAT
GGGCCTGCGCATCGACACCGCCGCCAACCTGGGCGAAGCCCGCGAGCTGTTGGCCCGCAATACCTACGACCTCTGCTTCA
CCGACATGCGCCTGCCCGACGGCAACGGCATCGACCTGGTCGGGGAGATAGCGCGCAACTATCCGGACACCCCGGTGGCC
ATGATCACCGCGTTCGGCAACATCGAACTGGCGGTGGAGGCGCTGAAGGCCGGCGCTTTCGATTTCGTCAGCAAGCCGGT
GGACCTGGCCGTGCTGCGCGGCCTGGTGAAGCACGCGCTGGAACTGAACAACACCGAGCGCGCACCGCCGCCGCCCCCGC
CGCCGGAACAGGCCAGCCGCCTGCTGGGCAGTTCGGCGGCGATGGATGCACTGCGCGAGACCATCGGCAAGGTGGCCCGC
AGCCAGGCACCGGTCTACATCATGGGCGAGTCCGGCACCGGCAAGGAGCTGGTGGCCCGCACCATCCACGAACAGGGCGC
GCGCGCGTCCGGCCCCTTCGTGCCGGTCAACTGCGGCGCCATTCCCGCCGAACTGATGGAAAGCGAGTTCTTCGGCCACA
AGAAGGGCAGCTTCACCGGCGCGCATGCGGACAAGCAGGGCCTGTTCCAGGCGGCCAACGGCGGCACCCTGTTCCTGGAC
GAGGTGGCCGAGCTGCCGCTGCCCATGCAGGTGAAGCTGCTGCGCGCCATCCAGGAGAAGGCGGTGCGCCCGGTCGGCGC
ATCCGGCGAGGTGCAGGTGGACGTGCGCATCCTCTCGGCCACGCACAAGGACCTGGGCGAGCTGGCGGCCGATGGCCGGT
TCCGCCACGACCTGTACTACCGCATCAACGTCATCGAGCTGCGCGTGCCGCCGCTGCGCGAGCGCACGGGCGATCTGGCG
CAGCTGACCACCGCCATCCTGGAGCGGCTGGCCGCCCAGCACGGGCGGATGGCGCCGTCGGTGTCGCCTGAGGCGATGGA
GGCGCTGGGCCGCTATCCGTTCCCGGGCAACGTGCGCGAGCTGGAGAACATTCTGGAGCGCGCACTGGCCATGTCCGAGG
GCCACAGCATCGAGATCGACGACCTGTACCTGCCGCAGGCGCCGGCCGGCAGGAAGTTCGGCGGCGATTTCAGCCCGGGC
GAAGTGGTGCGCGACGCGCCCGGCGCCGTCGACGTGGACCCGGCCGCGGGCGCCCTGCCCGACTACATCGAGCAGCTGGA
GCGCGCGGCCATCCAGAAGGCGCTGGAAGAGAACCGCTGGAACAAGACCAAGGCGGCGGCCCAGCTGGGCATCACCTTCC
GGGCCTTGCGCTACAAGTTGAAGAAGTTGGGGATGGAGTAA

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(423-463)

Response regulator receiver domain (Response_reg)

(8-114)

Sigma-54 interaction domain (Sigma54_activat)

(142-307)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

62.121

99.142

0.616
  pilR Acinetobacter baumannii strain A118

47.761

100

0.481