Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   MUY23_RS07350 Genome accession   NZ_CP095162
Coordinates   1489111..1491261 (-) Length   716 a.a.
NCBI ID   WP_002935100.1    Uniprot ID   -
Organism   Streptococcus suis strain TJS75     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1484111..1496261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUY23_RS07330 - 1485592..1486227 (-) 636 WP_024394859.1 hypothetical protein -
  MUY23_RS07335 - 1486842..1487591 (-) 750 WP_024394858.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  MUY23_RS07340 - 1487606..1488562 (-) 957 WP_002935098.1 GHKL domain-containing protein -
  MUY23_RS07345 - 1488934..1489089 (-) 156 WP_000794567.1 hypothetical protein -
  MUY23_RS07350 comA 1489111..1491261 (-) 2151 WP_002935100.1 peptide cleavage/export ABC transporter Regulator
  MUY23_RS07355 - 1491464..1491655 (-) 192 WP_002935101.1 hypothetical protein -
  MUY23_RS07360 - 1491744..1492016 (-) 273 WP_002935103.1 DUF3884 family protein -
  MUY23_RS07365 - 1492045..1493361 (-) 1317 WP_002935107.1 glycosyltransferase family 2 protein -
  MUY23_RS07370 - 1493549..1493710 (-) 162 WP_002935108.1 putative cross-wall-targeting lipoprotein signal domain-containing proteiin -
  MUY23_RS07375 - 1493993..1494583 (+) 591 WP_024401254.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
  MUY23_RS07380 - 1494580..1495425 (+) 846 WP_024383472.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 81601.36 Da        Isoelectric Point: 6.6744

>NTDB_id=675842 MUY23_RS07350 WP_002935100.1 1489111..1491261(-) (comA) [Streptococcus suis strain TJS75]
MKFSKRHYRAQVDSKDCGVAALAMVLEYYNSHYSLAELREMLGTTENGTTAFSIVSVANELGFDTEAIYADISLFDIEDI
KFPFIVHINKNNKFYHYYVIIGSDKKYIYIADPDPLIKLSKLTKEQFLAEWRGITILLKPNHEYKIKRKKTSFPSLFTLL
FNQKKLIFLIILLTLAVNFINIIGSYYLKRVIDSYIPKGELDFLNLMSISLIVIYLMQQFFVFGQGVLITVLSQILSKNI
MLSYIAHLFKLPLSFFATRRTGDIVSRFSDANIIIEVLSSIILSVILDVSIVTGVSIVLFLQSSYLFFIIIIAFPIYALV
IFLFMKPFRHSKTSVMEAGASLSSVLIEDINGIETIKSLTSEVDRYKKIKDEFSNYYKKITFYSRMELFQDVLKNFTQLL
FNVLILWQGAILVIEGKISLGSLITFNTLELYFLNSLENIINLQPKFQSASVAYNRLEEIYSVQSEFQDKFFITNFKLNS
SKIVISNLTYKYGYNQPLLKDINLVIEEGCKIAFVGLSGSGKTTLAKMLVNFMPPTYGSIEFGGININDIDKKTLRQLIN
YIPQKPYIFNGTILDNLLLGVEDEISFEEINKATEIAEIKSVIENLPLGYETELSPEHSILSGGQLQRVAIARALLTNPS
VLILDESTSNLDNLTERKIIDNLMSLDTTVIFIAHRLNITEQVERIFVIENGMIIENGNHEDLILKQGFYSKILKG

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=675842 MUY23_RS07350 WP_002935100.1 1489111..1491261(-) (comA) [Streptococcus suis strain TJS75]
ATGAAATTTTCGAAACGTCATTATCGTGCTCAAGTTGATTCAAAAGATTGTGGAGTAGCTGCTTTGGCCATGGTGTTAGA
ATACTATAATTCACATTATTCTTTAGCAGAACTTAGAGAAATGTTAGGTACAACTGAAAATGGGACTACTGCATTTAGTA
TAGTTTCTGTGGCAAATGAATTAGGGTTCGATACTGAAGCTATTTATGCAGATATTTCTTTATTTGACATAGAGGATATA
AAATTTCCATTTATTGTACATATAAATAAGAATAATAAATTTTATCATTACTATGTTATTATTGGCAGTGATAAAAAATA
TATTTATATAGCTGATCCTGATCCTCTGATAAAATTATCTAAACTAACTAAAGAACAGTTTCTTGCAGAATGGAGAGGGA
TAACTATATTATTAAAACCAAACCATGAGTACAAAATTAAAAGAAAGAAGACAAGTTTTCCTTCTTTATTTACTTTACTG
TTTAATCAAAAGAAATTAATTTTTTTAATTATATTATTAACTTTAGCAGTAAACTTTATCAATATAATTGGTTCATACTA
TTTAAAGAGAGTAATTGATTCTTATATTCCTAAAGGGGAGCTGGATTTTCTTAATCTAATGTCAATAAGCCTAATTGTTA
TTTATCTTATGCAACAGTTTTTTGTATTTGGTCAAGGGGTATTGATAACAGTTCTAAGTCAAATACTTTCAAAAAATATA
ATGCTGTCATATATTGCTCACCTTTTTAAACTTCCTCTATCTTTTTTTGCAACAAGAAGAACTGGCGATATTGTCTCTAG
ATTTTCAGATGCTAATATCATAATTGAAGTATTATCTAGTATAATTTTATCTGTAATACTAGATGTGTCAATAGTTACTG
GAGTATCAATTGTACTTTTTTTGCAAAGTAGTTATTTATTTTTTATTATAATTATTGCGTTTCCAATTTATGCTTTAGTA
ATTTTTTTATTCATGAAACCATTTAGACATAGTAAAACTAGTGTAATGGAAGCAGGAGCTTCACTTTCCTCAGTTCTTAT
AGAAGATATAAATGGAATAGAGACAATAAAATCTCTTACTAGTGAGGTTGATCGCTATAAAAAAATAAAAGACGAATTTA
GTAATTATTATAAAAAAATTACTTTTTATAGTAGAATGGAGTTGTTTCAAGATGTGTTAAAAAATTTTACTCAATTGTTG
TTTAATGTATTAATTTTATGGCAAGGTGCTATTTTAGTAATTGAAGGAAAAATATCATTGGGATCTTTGATAACCTTTAA
TACTTTAGAACTTTATTTTCTGAATTCACTGGAGAACATTATTAATTTACAACCTAAATTTCAATCAGCAAGTGTTGCGT
ATAATAGATTAGAAGAAATCTATTCGGTTCAATCAGAATTTCAGGATAAGTTCTTCATAACAAATTTTAAATTGAATTCT
AGTAAGATAGTAATTTCAAATTTAACCTACAAATATGGCTATAACCAGCCTCTATTAAAAGATATTAATTTAGTTATCGA
GGAAGGTTGTAAAATAGCATTTGTTGGTCTTTCTGGTTCAGGGAAAACAACTCTAGCAAAAATGTTAGTTAATTTTATGC
CTCCTACCTATGGAAGTATTGAATTTGGAGGAATTAATATTAATGATATTGATAAGAAGACTTTGAGACAATTGATTAAT
TATATACCCCAGAAACCTTATATTTTTAACGGTACTATATTAGATAATCTTTTATTAGGTGTTGAAGATGAAATTTCATT
TGAAGAGATTAATAAAGCTACTGAGATTGCCGAGATAAAATCTGTTATAGAGAATTTACCGTTAGGATATGAGACCGAAC
TTTCCCCTGAACATAGCATTTTGTCAGGAGGTCAACTTCAGAGAGTTGCTATTGCACGTGCATTATTAACCAATCCCTCG
GTATTAATCTTAGATGAGTCAACAAGTAATTTGGATAATTTAACGGAAAGAAAAATTATTGATAATTTAATGAGCTTAGA
TACAACTGTAATATTTATTGCTCACCGTCTTAATATAACAGAACAGGTTGAAAGGATATTTGTCATAGAAAATGGTATGA
TAATCGAAAACGGAAATCATGAAGATTTGATATTAAAACAAGGGTTTTATTCTAAAATATTAAAAGGTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(499-649)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(167-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

56.224

99.86

0.561
  comA Streptococcus gordonii str. Challis substr. CH1

56.224

99.86

0.561
  comA Streptococcus mitis SK321

55.664

99.86

0.556
  comA Streptococcus pneumoniae R6

55.385

99.86

0.553
  comA Streptococcus pneumoniae Rx1

55.385

99.86

0.553
  comA Streptococcus pneumoniae D39

55.385

99.86

0.553
  comA Streptococcus pneumoniae TIGR4

55.105

99.86

0.55
  comA/nlmT Streptococcus mutans UA159

49.157

99.441

0.489