Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MP619_RS02315 Genome accession   NZ_CP095081
Coordinates   424258..425019 (+) Length   253 a.a.
NCBI ID   WP_129555296.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain WJ001     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 419258..430019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS02300 (MP619_02290) - 420211..421206 (+) 996 WP_268227844.1 IS30 family transposase -
  MP619_RS02305 (MP619_02295) - 421286..423208 (+) 1923 WP_129555295.1 DUF2207 domain-containing protein -
  MP619_RS02310 (MP619_02300) - 423275..424114 (+) 840 WP_015057324.1 undecaprenyl-diphosphate phosphatase -
  MP619_RS02315 (MP619_02305) mecA 424258..425019 (+) 762 WP_129555296.1 adaptor protein MecA Regulator
  MP619_RS02320 (MP619_02310) - 425026..426195 (+) 1170 WP_115246691.1 MraY family glycosyltransferase -
  MP619_RS02325 (MP619_02315) sufC 426308..427078 (+) 771 WP_268227845.1 Fe-S cluster assembly ATPase SufC -
  MP619_RS02330 (MP619_02320) sufD 427175..428437 (+) 1263 WP_129555297.1 Fe-S cluster assembly protein SufD -
  MP619_RS02335 (MP619_02325) - 428468..429694 (+) 1227 WP_048327758.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29143.74 Da        Isoelectric Point: 4.0570

>NTDB_id=675079 MP619_RS02315 WP_129555296.1 424258..425019(+) (mecA) [Streptococcus dysgalactiae strain WJ001]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVDQEPEPLDYVH
YVLDFATLSEAVTFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=675079 MP619_RS02315 WP_129555296.1 424258..425019(+) (mecA) [Streptococcus dysgalactiae strain WJ001]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGATCTACCAGATAATT
TCAAAGATAGTGGCATGCTTAGTTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAGGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
AGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACTGCTGAGGAAGTGGATCAAGAACCAGAGCCGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCACTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACAAGAGCTTACTTACAAGAGCATGGCGTACAATTAATTCTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.4

98.814

0.636
  mecA Streptococcus thermophilus LMD-9

57.831

98.419

0.569
  mecA Streptococcus thermophilus LMG 18311

57.028

98.419

0.561
  mecA Streptococcus pneumoniae Rx1

47.451

100

0.478
  mecA Streptococcus pneumoniae D39

47.451

100

0.478
  mecA Streptococcus pneumoniae R6

47.451

100

0.478
  mecA Streptococcus pneumoniae TIGR4

47.451

100

0.478