Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   lgb_RS02215 Genome accession   NZ_CP094882
Coordinates   454191..454886 (+) Length   231 a.a.
NCBI ID   WP_019292077.1    Uniprot ID   A0A139ME49
Organism   Lactococcus petauri strain B1726     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 449191..459886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  lgb_RS02190 (lgb_00432) - 449424..450125 (+) 702 WP_019293249.1 DeoR/GlpR family DNA-binding transcription regulator -
  lgb_RS02195 (lgb_00433) pfkB 450122..451048 (+) 927 WP_019292080.1 1-phosphofructokinase -
  lgb_RS02200 (lgb_00434) - 451063..452967 (+) 1905 WP_019293248.1 PTS fructose transporter subunit IIABC -
  lgb_RS02205 (lgb_00435) - 453079..453321 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  lgb_RS02210 (lgb_00436) - 453538..454089 (+) 552 WP_019293247.1 YceD family protein -
  lgb_RS02215 (lgb_00437) covR 454191..454886 (+) 696 WP_019292077.1 response regulator transcription factor Regulator
  lgb_RS02220 (lgb_00438) covS 454974..456464 (+) 1491 WP_019293246.1 HAMP domain-containing histidine kinase Regulator
  lgb_RS02225 (lgb_00439) - 456860..458431 (+) 1572 WP_249663233.1 ABC transporter permease subunit -
  lgb_RS02230 (lgb_00440) - 458432..459169 (+) 738 WP_019292074.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27037.77 Da        Isoelectric Point: 5.2713

>NTDB_id=673937 lgb_RS02215 WP_019292077.1 454191..454886(+) (covR) [Lactococcus petauri strain B1726]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=673937 lgb_RS02215 WP_019292077.1 454191..454886(+) (covR) [Lactococcus petauri strain B1726]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TCGACTTAATGCTCCCAGAGCTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACATATTATTATG
ATGACTGCACGTGATTCAACTATGGACCGTGTAGCAGGTCTTGATATTGGAGCGGATGACTATATTACAAAACCATTCGC
AATTGAAGAATTGTTAGCGCGTGTCCGTTCACTCTTCCGTCGTGAAGACCATATCCACACGATTGAAAAATCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAAACAAACCGCACTGTACATCGCGGAAAAAAAGTTATTGACCTTACACGTCGT
GAATACGATTTGCTTTTGACCCTGATGCAAAATGTGGGTGATGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGCTATTTGCGTAACAAAATTGACGTGGAAGGCCGCG
AAAGTTATATTCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139ME49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.21

99.134

0.874
  covR Streptococcus salivarius strain HSISS4

67.241

100

0.675
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424