Detailed information NTG0673938

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: lgb_RS02220
• Genome accession: NZ_CP094882
• Coordinates: 454974..456464 (+)
• Length: 496 a.a.
• NCBI ID: WP_019293246.1
• Uniprot ID: A0AAJ2ML94
• Organism: Lactococcus petauri strain B1726
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 449974..461464

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
lgb_RS02195 (lgb_00433)	pfkB	450122..451048 (+)	927	WP_019292080.1	1-phosphofructokinase	-
lgb_RS02200 (lgb_00434)	-	451063..452967 (+)	1905	WP_019293248.1	PTS fructose transporter subunit IIABC	-
lgb_RS02205 (lgb_00435)	-	453079..453321 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
lgb_RS02210 (lgb_00436)	-	453538..454089 (+)	552	WP_019293247.1	YceD family protein	-
lgb_RS02215 (lgb_00437)	covR	454191..454886 (+)	696	WP_019292077.1	response regulator transcription factor	Regulator
lgb_RS02220 (lgb_00438)	covS	454974..456464 (+)	1491	WP_019293246.1	HAMP domain-containing histidine kinase	Regulator
lgb_RS02225 (lgb_00439)	-	456860..458431 (+)	1572	WP_249663233.1	ABC transporter permease subunit	-
lgb_RS02230 (lgb_00440)	-	458432..459169 (+)	738	WP_019292074.1	amino acid ABC transporter ATP-binding protein	-
lgb_RS02235 (lgb_00441)	murD	459309..460670 (+)	1362	WP_064305289.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56888.98 Da
• Isoelectric Point: 5.2995

>NTDB_id=673938 lgb_RS02220 WP_019293246.1 454974..456464(+) (covS) [Lactococcus petauri strain B1726]
MVKFFDSKKKKAENLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESKLS
EDNLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSTHAVRTFGEYSGYLV
ERPVHSKKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLNLTVENYLTPGSLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
IVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=673938 lgb_RS02220 WP_019293246.1 454974..456464(+) (covS) [Lactococcus petauri strain B1726]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAGCAGAAAATCTGCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
CTTTGCAAATACGATTTTTTGTTTTATAACCTTCACTATTTTTACAGTATTAGTTTATCAACTGACCATAACAACCTTCA
TCAATTCTGAAAAAGAGGACATGATGAAAGCTCTGGACAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCAAACTGTCG
GAGGACAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCATCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAGTCTTTTTATGTCTTTGATGTCGGTGAAAATTTGATTTATTCGACCAATTCGT
ATGGTTTCCCGCTAAGGAAAGATGTGGGGGATTCTACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTT
GAACGACCCGTTCATTCTAAGAAAACAGGGAAACTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTACAG
CGTGCGAACAAAGCTGCTGATTGCCCTGATTATCTTAGAAATTATTGCTCTCTTTATTGCTCAGTTTGTCGGTTATTTTA
TGGCAAGTCGCTATATCAAGCCTCTAGAGCGTTTGCACGATGCGATTACTACACGTGCCAATAATTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGCGATGAAATTGAAGAACTGGCGACTGTTTATAACGACATGATGATTAAGCTTAACGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGCTACGTACGCCACTTGCAGTTTTAGATGGTCATT
TGAATCTCTTGAATCGATGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGC
ACGATGAGAACGATGTTAGAGGAGATGCTTGCATTGGCCCGTCTTGAAAGCATTGATTTTCAAGATGAAGATCTGATCTG
TGATCCAACAGAAGTTTCTAATTTTCTTAAGAAAAACTTTCTCCTTATTCATCCTGATTTAAATTTAACTGTTGAGAATT
ACTTGACGCCGGGTAGTTTGGCTCATATTTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGACAAATACATTATTACAACAGTTGAGGA
TCGTGGCTATGGCATTAGTCAAGAAGATTTAAAACATGTCTTTGAGCGCTTTTTCCGTGCCGATAAAGCACGAAATCGAG
ATATAGGTGGAACAGGTCTTGGTCTGTCTATTATCCAACGCATAGTGGAAAACTATGACGGGGATGTCAGTGTGACTTCC
ATTGTAGGCGAAGGATCGAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.823	100	0.56