Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SITYG_RS02470 Genome accession   NZ_AP014880
Coordinates   476761..478635 (+) Length   624 a.a.
NCBI ID   WP_096362578.1    Uniprot ID   A0AAD1FIW8
Organism   Streptococcus intermedius strain TYG1620     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 471761..483635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS02455 (SITYG_04640) fmt 473767..474702 (+) 936 WP_096362576.1 methionyl-tRNA formyltransferase -
  SITYG_RS02460 (SITYG_04650) rsmB 474692..476005 (+) 1314 WP_096362577.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SITYG_RS02465 (SITYG_04660) - 476024..476764 (+) 741 WP_003073671.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SITYG_RS02470 (SITYG_04670) stkP 476761..478635 (+) 1875 WP_096362578.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SITYG_RS02475 (SITYG_04690) liaF 478898..479596 (+) 699 WP_009568136.1 cell wall-active antibiotics response protein LiaF -
  SITYG_RS02480 (SITYG_04700) - 479593..480588 (+) 996 WP_096362579.1 sensor histidine kinase -
  SITYG_RS02485 (SITYG_04710) - 480590..481222 (+) 633 WP_009568138.1 response regulator transcription factor -
  SITYG_RS02490 (SITYG_04720) - 481262..482662 (+) 1401 WP_003078255.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SITYG_RS02495 (SITYG_04730) - 482664..483056 (+) 393 WP_096362580.1 S1 RNA-binding domain-containing protein -
  SITYG_RS02500 (SITYG_04740) - 483176..483493 (-) 318 WP_003073656.1 DUF960 domain-containing protein -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67668.82 Da        Isoelectric Point: 9.6670

>NTDB_id=67242 SITYG_RS02470 WP_096362578.1 476761..478635(+) (stkP) [Streptococcus intermedius strain TYG1620]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTVKADTKTLPKVSQNTLTSASKPPATSTKEAVD
NQTKPKPKPKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTVAQARSAIEAAGLKVGKEKDEYSDSAK
KDSVIRTNPQAGTQRREGSTVDLIVSKGPKTFTMEDYSGQKKADAINSLVQKYKVSKGLIKIEEVESSDYAAGTVVSQTP
AAGSTYDLTSKNRITLKVAKTVSSVTMPSYIGSTYEFAYNNLTEVIGVQGANVEKRIVTTAPAGTQAHTIIKQSPEAKRP
LNLKNDRIVLYVYEPKTEESSTSESSSQSGSSSNKNSPSSSSSSSSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=67242 SITYG_RS02470 WP_096362578.1 476761..478635(+) (stkP) [Streptococcus intermedius strain TYG1620]
ATGATTCAAGTCGGCAAAATCTTTGCCGGACGATATAGAATCATCAAACAAATCGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCGAAAGATTTGATTTTAGACGGGGAAGAAGTCGCAGTTAAGGTTCTAAGAACCAACTACCAGACAGATCCGATTG
CTGTAGCGCGTTTTCAAAGAGAGGCGCGAGCCATGGCAGATTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGCCAGCAATATCTAGCAATGGAGTATGTGGCTGGACTTGACTTGAAACGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTGCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCGCATACGCATGGGATTGTTC
ACCGTGATTTAAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACTGACTTTGGAATTGCAGTAGCT
TTTGCAGAAACGAGTTTAACCCAGACAAATTCAATGCTGGGATCTGTACATTATCTATCACCAGAACAGGCACGTGGATC
AAAAGCAACAGTTCAAAGTGATATTTATGCTATGGGGATTATTTTCTATGAAATGCTGACAGGTCACATTCCTTATGATG
GGGATAGTGCTGTGACGATTGCACTGCAGCATTTCCAAAAACCCCTTCCTTCTGTAATTGCTGAAAATCCAAATGTTCCA
CAAGCATTAGAAAATGTGGTTATCAAGGCAACGGCAAAAAAATTAACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
TGACTTATCTAGTTGTTTATCTGCTGATCGTCGAAATGAGAAGAAATTAGTTTTTGATGATACTGTTAAAGCAGACACTA
AGACGCTTCCTAAAGTATCACAGAATACGTTGACTTCAGCGTCTAAACCGCCTGCTACATCTACAAAAGAAGCTGTTGAT
AATCAAACTAAGCCTAAACCAAAACCAAAGAAAAAACGTCGTTTAAGAACACGTTATAAAGTGTTGTTGTCGGCAGTAGT
CTTAGTTATTGCAGCTTTGGTGGCTTTAGTCTATTTGAGTCCCTCAAATGTAAAAATACCAGATGTTACTGGAAAAACCG
TCGCGCAAGCACGTTCCGCGATTGAAGCTGCAGGTTTGAAAGTTGGCAAGGAGAAAGACGAATACAGTGATTCTGCTAAG
AAAGATTCTGTCATTCGTACGAATCCACAAGCGGGAACACAACGTCGCGAAGGAAGCACAGTAGATTTGATTGTCTCAAA
AGGGCCGAAAACATTTACTATGGAAGATTATAGCGGTCAGAAAAAAGCAGATGCTATCAACAGTTTGGTGCAAAAATACA
AAGTTTCAAAGGGCTTGATTAAAATTGAAGAAGTCGAAAGTAGTGACTATGCAGCAGGAACTGTTGTTAGTCAGACGCCG
GCAGCAGGTAGTACGTATGATTTGACTTCAAAAAATCGGATTACGTTAAAAGTAGCGAAGACGGTTTCAAGTGTTACAAT
GCCAAGTTATATAGGTTCCACTTATGAATTTGCCTATAATAACCTTACCGAAGTTATTGGCGTTCAAGGAGCTAATGTTG
AAAAACGAATAGTTACAACAGCTCCAGCAGGAACACAGGCACATACGATTATTAAACAAAGCCCAGAAGCAAAGAGGCCT
CTAAATTTAAAAAATGATCGTATTGTCTTATATGTATATGAGCCAAAAACTGAAGAATCATCTACATCTGAAAGTAGTTC
GCAATCTGGAAGTAGTTCAAATAAAAATAGTCCATCATCTAGTAGTTCGTCGAGTAGCGGTAACGATGGATCAAGTTCGA
AAACACCAGACACAAGCGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(433-500)

PASTA domain (PASTA)

(505-573)

PASTA domain (PASTA)

(364-427)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.381

93.429

0.62
  stkP Streptococcus pneumoniae D39

66.038

93.429

0.617
  stkP Streptococcus pneumoniae R6

66.038

93.429

0.617
  stkP Streptococcus pneumoniae Rx1

65.866

93.429

0.615
  pknB Streptococcus mutans UA159

59.658

93.75

0.559
  stkP/pknB Streptococcus salivarius strain HSISS4

59.294

86.218

0.511

Multiple sequence alignment