Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MP387_RS03510 Genome accession   NZ_CP094226
Coordinates   723325..724062 (+) Length   245 a.a.
NCBI ID   WP_242747727.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 718325..729062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS03500 (MP387_03500) - 719149..721677 (+) 2529 WP_242747723.1 MBL fold metallo-hydrolase -
  MP387_RS03505 (MP387_03505) - 721724..723202 (-) 1479 WP_242747725.1 oligosaccharide flippase family protein -
  MP387_RS03510 (MP387_03510) mecA 723325..724062 (+) 738 WP_242747727.1 adaptor protein MecA Regulator
  MP387_RS03515 (MP387_03515) - 724214..725500 (+) 1287 WP_242747730.1 homoserine dehydrogenase -
  MP387_RS03520 (MP387_03520) thrB 725502..726371 (+) 870 WP_242747733.1 homoserine kinase -
  MP387_RS03525 (MP387_03525) msrB 726631..727569 (+) 939 WP_242747736.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28338.11 Da        Isoelectric Point: 4.0759

>NTDB_id=668100 MP387_RS03510 WP_242747727.1 723325..724062(+) (mecA) [Streptococcus oralis strain 1648]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETENKKEPYIYYILRFA
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=668100 MP387_RS03510 WP_242747727.1 723325..724062(+) (mecA) [Streptococcus oralis strain 1648]
ATGAAGATGAAACAAATTAGTGATACAACACTAAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTCGACGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATCTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCAGATGAATTTCT
CAAAACCTTGGAAAAGAGCATTGCAGATAAGACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACGGAGAATAAGAAAGAACCTTATATCTACTATATCCTACGCTTTGCA
AGCCTTGCTGACTTAGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGACA
CTATTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGATAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATATTGATTAACCATGATGCAGTTCTCGGT
CTGCAAAAAATCGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.612

100

0.906
  mecA Streptococcus pneumoniae D39

90.612

100

0.906
  mecA Streptococcus pneumoniae R6

90.612

100

0.906
  mecA Streptococcus pneumoniae TIGR4

90.204

100

0.902
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.486
  mecA Streptococcus mutans UA159

48.571

100

0.486
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.482

Multiple sequence alignment