Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   LOOC260_RS03665 Genome accession   NZ_AP014680
Coordinates   767093..769270 (+) Length   725 a.a.
NCBI ID   WP_041093105.1    Uniprot ID   A0A0A1GWQ1
Organism   Paucilactobacillus hokkaidonensis JCM 18461 strain LOOC260     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 762093..774270
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOOC260_RS12370 (LOOC260_107500) - 762341..762496 (+) 156 WP_156406639.1 bacteriocin -
  LOOC260_RS03645 (LOOC260_107510) - 762511..762693 (+) 183 WP_041093100.1 hypothetical protein -
  LOOC260_RS11995 (LOOC260_107520) - 763165..763287 (+) 123 WP_082232286.1 bacteriocin -
  LOOC260_RS11835 (LOOC260_107530) - 763405..764652 (+) 1248 WP_162182089.1 GHKL domain-containing protein -
  LOOC260_RS03655 (LOOC260_107540) - 764656..765393 (+) 738 WP_041093102.1 response regulator transcription factor -
  LOOC260_RS12220 (LOOC260_107550) - 766203..766370 (+) 168 WP_156406638.1 hypothetical protein -
  LOOC260_RS12225 (LOOC260_107560) - 766391..766567 (+) 177 WP_156406637.1 hypothetical protein -
  LOOC260_RS03665 (LOOC260_107580) comA/nlmT 767093..769270 (+) 2178 WP_041093105.1 peptide cleavage/export ABC transporter Regulator
  LOOC260_RS03670 (LOOC260_107590) - 769280..770656 (+) 1377 WP_041093107.1 bacteriocin secretion accessory protein -
  LOOC260_RS03675 (LOOC260_107600) - 770712..771062 (+) 351 WP_041093108.1 hypothetical protein -
  LOOC260_RS03680 (LOOC260_107610) - 771100..772173 (-) 1074 WP_041093110.1 dipeptide epimerase -
  LOOC260_RS03685 (LOOC260_107620) - 772265..772624 (-) 360 WP_041093112.1 hypothetical protein -
  LOOC260_RS03690 (LOOC260_107630) - 772784..773119 (-) 336 WP_041093113.1 hypothetical protein -
  LOOC260_RS03695 (LOOC260_107640) - 773106..773408 (-) 303 WP_041093115.1 hypothetical protein -
  LOOC260_RS03700 (LOOC260_107650) - 773602..774084 (+) 483 WP_041093117.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 725 a.a.        Molecular weight: 80566.93 Da        Isoelectric Point: 6.4355

>NTDB_id=66791 LOOC260_RS03665 WP_041093105.1 767093..769270(+) (comA/nlmT) [Paucilactobacillus hokkaidonensis JCM 18461 strain LOOC260]
MTFIWNKIKFKYVPQVDERDCGVAALDMVLEAYHSDYSLASLRELAKTDMEGTTALGIVRAAEQIGFETQVVKADMSLFD
LDDIPYPFIAHVIKPGGLLHYYTIFSKTSKCVILGDPDPSVGLIRMSKKQFQGEWDGVAIFLAPLPEYHPKKESKRNLFA
LIPLLLKQRLLVTQIILASLLVTLISIVGSYYLQGIIDTYIPGGLKNTLVIISIGIITAYVIQQFLSFAENYLLMVMGQR
LSIDIILGYIRHIFELPMKFFGTRRTGEIVSRFTDASQIIDALASTIISLFLDVGIVVIVGIVLAFQNINLMLLTLISIP
LYAIIIFVFVGSFDKLNNDRMESNAVLSSSIIEDIDGIETIKSLNSEQTTYRKIDREFVDYLKKSFKYEKLSITQEALKE
GLQLVLNVFVLWFGSTMVIDGKMTLGQLVTFNALLSYFTTPLQSIIGLQTKLQAAKVANNRLNEVYSVDSEFTKVSAFNE
KPKSLTNSEITLTNVKFRYGFGNYALDDISLTIKAGAKIALVGASGSGKSTLVKLLVRFFESESGQIRFGQIPLNEINQK
KLRATINYLPQEPYIFSGTIYENLLLGCSDKNVGIQTINNALEIAAIKDDIEAMQLGLETPLSADGSGISGGQKQRIAIA
RAVLADTPVMIMDESTSNLDLITERKIIGNLLAFTNKTIIFVAHRLTIAEMVDDIYVMNHGKVIEHGSHEKLRNAGGFYS
KLLND

Nucleotide


Download         Length: 2178 bp        

>NTDB_id=66791 LOOC260_RS03665 WP_041093105.1 767093..769270(+) (comA/nlmT) [Paucilactobacillus hokkaidonensis JCM 18461 strain LOOC260]
ATGACTTTTATTTGGAATAAAATAAAATTTAAGTACGTGCCTCAAGTCGATGAACGAGATTGTGGTGTTGCAGCTTTAGA
TATGGTACTAGAGGCATATCATTCAGATTATTCATTAGCGTCTTTAAGAGAATTAGCAAAAACGGATATGGAAGGAACCA
CAGCTTTAGGAATTGTAAGGGCAGCTGAGCAAATTGGATTTGAAACTCAAGTGGTCAAGGCTGATATGTCATTATTTGAT
TTGGATGATATTCCGTATCCGTTCATTGCTCATGTTATTAAACCGGGCGGTCTCCTTCATTACTACACTATTTTTTCAAA
GACCAGTAAGTGTGTTATTTTGGGTGATCCAGATCCTTCAGTTGGTCTGATCAGAATGAGCAAAAAGCAGTTTCAAGGTG
AATGGGATGGGGTTGCCATCTTTTTAGCACCTTTGCCTGAATATCATCCTAAAAAGGAATCCAAAAGAAATTTATTTGCT
TTGATTCCATTATTATTGAAACAGCGATTGTTAGTAACTCAAATAATTTTGGCATCATTATTGGTTACACTAATCAGTAT
CGTGGGTTCATATTATCTGCAGGGTATCATTGATACATATATTCCTGGTGGACTTAAAAATACATTAGTAATTATATCTA
TTGGCATTATTACGGCGTACGTTATACAGCAGTTTTTATCATTTGCAGAAAACTATCTATTAATGGTGATGGGACAAAGA
TTATCCATTGATATAATTTTAGGGTATATCCGTCACATCTTTGAATTGCCAATGAAATTCTTTGGAACCAGAAGAACTGG
GGAAATTGTTTCTAGATTTACAGATGCTAGCCAAATCATTGATGCTTTAGCAAGCACAATTATTTCTTTATTTTTAGATG
TTGGAATTGTTGTTATAGTAGGAATTGTGTTGGCGTTTCAGAATATTAATTTGATGCTCTTAACATTAATTTCAATACCA
CTGTATGCCATCATTATTTTTGTGTTTGTCGGTAGTTTTGACAAATTAAATAATGATCGGATGGAATCAAATGCCGTTTT
GAGTTCATCAATCATTGAGGATATAGACGGAATAGAAACGATTAAATCTTTAAATAGCGAGCAGACCACCTACCGAAAAA
TTGATCGTGAGTTTGTGGATTATTTGAAAAAATCATTTAAATATGAAAAATTAAGTATCACACAAGAAGCACTCAAAGAA
GGATTACAGTTGGTACTCAATGTATTTGTACTCTGGTTTGGTTCAACCATGGTTATTGATGGAAAAATGACTTTAGGTCA
GCTGGTTACTTTCAATGCGTTATTAAGTTATTTCACAACTCCGCTTCAGTCAATAATCGGATTACAAACTAAATTGCAAG
CGGCCAAGGTGGCTAACAATCGACTCAACGAAGTTTATTCAGTAGATTCTGAATTTACTAAAGTTTCCGCGTTTAATGAA
AAACCTAAGTCATTGACAAATTCGGAAATTACACTAACAAATGTTAAATTCAGGTATGGTTTTGGCAATTATGCGTTAGA
TGATATTTCACTTACTATTAAAGCGGGTGCCAAAATTGCTCTTGTAGGTGCTAGTGGTTCTGGTAAATCTACTTTGGTGA
AATTATTAGTTAGATTTTTTGAATCTGAGTCCGGCCAAATAAGATTTGGGCAGATACCATTAAATGAAATTAACCAAAAG
AAATTGAGAGCAACCATAAATTATTTGCCCCAAGAACCATATATATTTTCTGGAACGATTTATGAAAATTTATTACTTGG
TTGCAGTGATAAAAATGTAGGAATCCAAACAATTAATAACGCGTTAGAAATTGCGGCAATCAAAGATGATATCGAAGCAA
TGCAGTTGGGCTTGGAAACGCCACTCTCAGCGGACGGCAGTGGTATCTCAGGTGGGCAAAAGCAGCGTATTGCAATTGCT
AGAGCAGTTTTAGCTGATACACCGGTTATGATTATGGATGAATCTACAAGTAATTTAGATTTAATTACGGAACGTAAAAT
AATTGGAAATTTATTAGCTTTCACGAATAAAACAATTATTTTTGTCGCTCATCGTTTAACCATTGCAGAAATGGTTGATG
ATATTTACGTAATGAACCACGGTAAAGTTATTGAACATGGTTCACATGAAAAATTGCGTAATGCAGGTGGCTTTTATTCG
AAACTATTAAATGATTGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(9-144)

ABC transporter (ABC_tran)

(506-657)

ABC transporter transmembrane region (ABC_membrane)

(175-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0A1GWQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

57.5

99.31

0.571
  comA Streptococcus mitis SK321

57.542

98.759

0.568
  comA Streptococcus mitis NCTC 12261

57.402

98.759

0.567
  comA Streptococcus pneumoniae R6

57.263

98.759

0.566
  comA Streptococcus pneumoniae D39

57.263

98.759

0.566
  comA Streptococcus pneumoniae Rx1

57.263

98.759

0.566
  comA Streptococcus pneumoniae TIGR4

57.123

98.759

0.564
  comA Streptococcus gordonii str. Challis substr. CH1

56.704

98.759

0.56

Multiple sequence alignment