Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LOOC260_RS00135 Genome accession   NZ_AP014680
Coordinates   30117..31007 (+) Length   296 a.a.
NCBI ID   WP_420836085.1    Uniprot ID   -
Organism   Paucilactobacillus hokkaidonensis JCM 18461 strain LOOC260     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 25117..36007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOOC260_RS00120 (LOOC260_100250) - 26631..27938 (+) 1308 WP_041091989.1 YycH family regulatory protein -
  LOOC260_RS00125 (LOOC260_100260) - 27957..28790 (+) 834 WP_041091991.1 two-component system regulatory protein YycI -
  LOOC260_RS00130 (LOOC260_100270) - 28804..29610 (+) 807 WP_041091993.1 MBL fold metallo-hydrolase -
  LOOC260_RS00135 (LOOC260_100280) htrA 30117..31007 (+) 891 WP_420836085.1 S1C family serine protease Regulator
  LOOC260_RS00140 (LOOC260_100290) carB 31109..34192 (-) 3084 WP_041091995.1 carbamoyl-phosphate synthase large subunit -
  LOOC260_RS00145 (LOOC260_100300) - 34185..35267 (-) 1083 WP_041091996.1 carbamoyl phosphate synthase small subunit -

Sequence

Protein


Download         Length: 296 a.a.        Molecular weight: 30506.46 Da        Isoelectric Point: 9.0522

>NTDB_id=66787 LOOC260_RS00135 WP_420836085.1 30117..31007(+) (htrA) [Paucilactobacillus hokkaidonensis JCM 18461 strain LOOC260]
MYKKNGNTAYVVTNNHVVSGSSKLEVILSSGKKINAKIVGTDATTDLAVLKINAANVSTVASFGNSNQIEAGQSVLAIGS
PLGSDYATSVTEGIISAKKRTVQVQDNSGSTTGNASVIQTDAAINPGNSGGPLINLAGQVIGINSMKLSSDEEGTSVEGM
GFSIPSNEVVSVINQLVKNGKITRPALGIELVGLDNISAAQQKSILKVPSSVTKGIVVMKILSPSAAGNAGLKKYDVITE
LDGEKVTDEAKLKDALYKHKIGDSVSVKYYRGGDLKTATIKLSESTSSLSSESSSE

Nucleotide


Download         Length: 891 bp        

>NTDB_id=66787 LOOC260_RS00135 WP_420836085.1 30117..31007(+) (htrA) [Paucilactobacillus hokkaidonensis JCM 18461 strain LOOC260]
ATTTATAAAAAGAACGGTAATACTGCCTATGTTGTTACGAATAATCACGTTGTTTCAGGATCTTCCAAATTGGAAGTTAT
TTTGAGTAGTGGTAAAAAGATTAATGCCAAAATTGTGGGAACAGATGCAACGACTGACTTAGCCGTTTTAAAGATTAATG
CTGCTAATGTTTCAACGGTTGCTAGTTTTGGCAATTCCAATCAAATTGAAGCTGGTCAAAGCGTTCTAGCAATTGGTTCG
CCACTGGGATCAGATTATGCGACCTCAGTTACTGAGGGAATTATTTCGGCCAAGAAGCGAACGGTCCAAGTGCAGGACAA
TTCTGGTAGCACCACTGGTAATGCAAGTGTTATTCAAACTGATGCTGCAATCAATCCAGGTAACTCAGGTGGACCACTGA
TCAACCTGGCTGGACAAGTAATCGGCATTAATTCAATGAAGTTGTCTTCAGATGAGGAAGGAACTAGCGTTGAAGGAATG
GGCTTTTCAATTCCTAGTAATGAAGTTGTGAGTGTGATTAACCAGCTAGTTAAGAATGGTAAAATTACACGACCAGCATT
AGGAATTGAGCTAGTGGGACTGGATAATATATCGGCCGCACAACAAAAATCAATCCTAAAGGTACCATCTAGCGTTACAA
AGGGGATCGTGGTAATGAAGATCTTATCACCTTCTGCAGCTGGAAATGCGGGATTGAAAAAATATGATGTGATTACTGAG
CTCGATGGTGAGAAGGTTACTGATGAAGCGAAGCTAAAGGATGCTTTGTATAAACATAAAATAGGCGACTCTGTTTCAGT
TAAATATTATCGCGGTGGAGATTTGAAGACAGCAACAATTAAACTGTCAGAATCAACGAGTTCGTTAAGTAGCGAGAGTA
GTAGTGAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(6-143)

PDZ domain (PDZ_2)

(185-282)

Peptidase family M50 (Peptidase_M50)

(130-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

53.767

98.649

0.53
  htrA Streptococcus mitis NCTC 12261

50.172

98.311

0.493
  htrA Streptococcus pneumoniae D39

49.828

98.311

0.49
  htrA Streptococcus pneumoniae TIGR4

49.828

98.311

0.49
  htrA Streptococcus pneumoniae R6

49.828

98.311

0.49
  htrA Streptococcus pneumoniae Rx1

49.828

98.311

0.49
  htrA Streptococcus gordonii str. Challis substr. CH1

49.147

98.986

0.486

Multiple sequence alignment