Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   MO978_RS11505 Genome accession   NZ_CP093959
Coordinates   2259599..2260825 (+) Length   408 a.a.
NCBI ID   WP_289421825.1    Uniprot ID   -
Organism   Lactococcus lactis strain FAM 17919     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2254599..2265825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MO978_RS11480 (MO978_11465) - 2255689..2256492 (-) 804 WP_003130590.1 phosphatidate cytidylyltransferase -
  MO978_RS11485 (MO978_11470) - 2256492..2257226 (-) 735 WP_003130589.1 isoprenyl transferase -
  MO978_RS11490 (MO978_11475) yajC 2257600..2257932 (-) 333 WP_003130588.1 preprotein translocase subunit YajC -
  MO978_RS11495 (MO978_11480) - 2258027..2258725 (-) 699 WP_003130586.1 DNA alkylation repair protein -
  MO978_RS11500 (MO978_11485) rlmH 2258744..2259223 (-) 480 WP_003130585.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  MO978_RS11505 (MO978_11490) htrA 2259599..2260825 (+) 1227 WP_289421825.1 S1C family serine protease Regulator
  MO978_RS11510 (MO978_11495) - 2260951..2261949 (+) 999 WP_010906330.1 glycosyltransferase family 4 protein -
  MO978_RS11515 (MO978_11500) - 2262075..2263415 (+) 1341 WP_003130580.1 glycosyltransferase family 4 protein -
  MO978_RS11520 (MO978_11505) - 2263523..2263747 (+) 225 WP_003130579.1 YkuJ family protein -
  MO978_RS11525 (MO978_11510) - 2263889..2264893 (+) 1005 WP_014570826.1 hypothetical protein -
  MO978_RS11530 (MO978_11515) - 2264934..2265686 (-) 753 WP_003130577.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 41665.00 Da        Isoelectric Point: 5.1538

>NTDB_id=665961 MO978_RS11505 WP_289421825.1 2259599..2260825(+) (htrA) [Lactococcus lactis strain FAM 17919]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQSANNSRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKDNS
QSSDFSSIFGGNSGSSSSTDGLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGKKVKASVVGYDEYTDLAV
LKISSEHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTNINAIQTDAAINPGNSG
GALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLEADGKISRPALGIRMVDLSQLSTNDSSQLKLPS
SVTGGVVVYSVQSGLPAASAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSNTADVKLSKSTNDLE
TSSSSSSN

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=665961 MO978_RS11505 WP_289421825.1 2259599..2260825(+) (htrA) [Lactococcus lactis strain FAM 17919]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACAGGTGTCGTGGGCGGAGCCATCGCACTTGGAGGAAGTGCAATCTA
TCAAAGCACTACAAATCAATCGGCAAATAATAGTCGTTCAAATACAACTAGTACAAAGGTTAGTAACGTTTCGGTAAATG
TCAATACCGATGTTACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAAGATAACTCA
CAAAGTAGTGACTTCAGTTCAATTTTTGGTGGAAATAGCGGTTCAAGTTCATCGACTGATGGCTTACAGCTTTCTAGTGA
AGGCTCTGGTGTCATCTACAAAAAATCTGGTGGTGATGCTTACGTTGTAACTAACTACCACGTTATTGCTGGTAATAGCT
CACTTGATGTTCTGCTTTCTGGTGGAAAAAAAGTCAAAGCTTCTGTGGTTGGTTATGATGAATACACAGACCTTGCTGTT
CTTAAAATCAGTTCTGAACATGTCAAAGATGTGGCGACATTCGCTGATTCTAGTAAATTAACAATTGGTGAACCTGCCAT
TGCCGTTGGCTCACCTTTAGGTAGTCAATTTGCAAACACCGCAACTGAAGGAATTTTATCTGCAACAAGCCGTCAAGTGA
CTTTGACCCAAGAAAATGGTCAAACAACTAATATCAATGCAATTCAAACAGATGCTGCCATTAACCCTGGTAACTCTGGA
GGGGCTTTGATTAATATTGAAGGACAAGTTATTGGAATTACTCAAAGTAAAATTACAACAACTGAAGATGGTTCTACTTC
TGTCGAAGGTTTAGGATTTGCGATTCCTTCTAATGATGTCGTAAATATCATTAATAAACTTGAAGCTGATGGTAAGATTT
CACGCCCTGCTTTAGGTATCCGAATGGTTGACCTTTCACAATTATCAACAAATGACAGTTCTCAATTGAAACTACCAAGC
AGTGTAACAGGTGGGGTTGTTGTTTACTCCGTCCAATCTGGACTTCCTGCTGCCTCAGCTGGTTTGAAAGCTGGAGATGT
AATTACAAAGGTTGGCGATACAGCAGTAACTTCTTCAACAGACTTGCAAAGTGCTCTTTACTCACACAATATCAATGATA
CAGTAAAAGTTACTTATTATCGTGATGGTAAATCAAATACAGCAGATGTTAAACTTTCTAAATCAACCAATGACTTAGAA
ACAAGCAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Peptidase family M50 (Peptidase_M50)

(232-396)

Trypsin-like peptidase domain (Trypsin_2)

(108-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

56.283

93.627

0.527
  htrA Streptococcus gordonii str. Challis substr. CH1

54.476

95.833

0.522
  htrA Streptococcus pneumoniae D39

58.309

84.069

0.49
  htrA Streptococcus pneumoniae TIGR4

58.309

84.069

0.49
  htrA Streptococcus pneumoniae R6

58.309

84.069

0.49
  htrA Streptococcus pneumoniae Rx1

58.309

84.069

0.49
  htrA Streptococcus mutans UA159

53.261

90.196

0.48