Detailed information NTG0066578

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: SCSC_RS07455
• Genome accession: NZ_AP014647
• Coordinates: 1513986..1515053 (-)
• Length: 355 a.a.
• NCBI ID: WP_006268109.1
• Uniprot ID: F9P7H5
• Organism: Streptococcus constellatus subsp. constellatus strain CCUG 24889
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1508986..1520053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCSC_RS07435 (SCSC_1528)	-	1509563..1511017 (+)	1455	WP_006270225.1	sucrose-6-phosphate hydrolase	-
SCSC_RS07440 (SCSC_1529)	-	1510998..1511963 (+)	966	WP_006270237.1	LacI family DNA-binding transcriptional regulator	-
SCSC_RS07445 (SCSC_1530)	-	1512048..1512866 (-)	819	WP_006270209.1	Cof-type HAD-IIB family hydrolase	-
SCSC_RS07450 (SCSC_1531)	amiF	1513052..1513975 (-)	924	WP_003070566.1	ATP-binding cassette domain-containing protein	Regulator
SCSC_RS07455 (SCSC_1532)	amiE	1513986..1515053 (-)	1068	WP_006268109.1	ABC transporter ATP-binding protein	Regulator
SCSC_RS07460 (SCSC_1533)	amiD	1515062..1515988 (-)	927	WP_006270263.1	oligopeptide ABC transporter permease OppC	Regulator
SCSC_RS07465 (SCSC_1534)	amiC	1515988..1517484 (-)	1497	WP_006268182.1	ABC transporter permease	Regulator
SCSC_RS07470 (SCSC_1535)	amiA3	1517848..1519827 (-)	1980	WP_006270242.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39582.24 Da
• Isoelectric Point: 4.7899

>NTDB_id=66578 SCSC_RS07455 WP_006268109.1 1513986..1515053(-) (amiE) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MTQEKNVILTARDIVVEFDVRDKVLTAIRGVSLDLIEGEVLALVGESGSGKSVLTKTFTGMLEDNGRVAQGSINYRGQDL
TKLKSNKDWEPIRGVKIATIFQDPMTSLDPINTIGSQITEVIVKHQKKTAKEAKEMAIDYMNKVGIPDAEKRFSEYPFQY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIIDLLKSLQQEYQFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEDVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYSHLQGDAFALRSDYAMEIDFEEKPPQIYVSDTHWAK
TWLLHENAPKVNKPAVIDDLHEKISSKMGFAHLDA

Nucleotide

• Length: 1068 bp

>NTDB_id=66578 SCSC_RS07455 WP_006268109.1 1513986..1515053(-) (amiE) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGACACAAGAAAAAAATGTAATATTGACTGCCCGCGATATTGTCGTGGAATTTGACGTTCGTGATAAAGTCTTAACCGC
CATTCGTGGTGTATCACTTGACCTCATCGAAGGTGAAGTTCTTGCTCTCGTAGGAGAGTCAGGTTCTGGTAAATCTGTTT
TAACAAAGACTTTTACTGGAATGTTAGAGGATAATGGTCGAGTAGCGCAAGGATCGATTAACTATCGTGGACAAGATTTG
ACAAAATTGAAATCCAATAAAGATTGGGAACCTATTCGTGGTGTTAAAATTGCGACTATTTTCCAAGACCCAATGACAAG
TTTAGACCCAATTAATACGATTGGTAGCCAGATTACAGAAGTTATTGTAAAACATCAAAAGAAAACGGCAAAAGAAGCGA
AGGAAATGGCTATTGACTATATGAATAAAGTCGGTATTCCTGATGCTGAAAAGCGTTTTAGTGAGTATCCTTTCCAATAT
TCAGGAGGAATGCGTCAACGGATCGTTATTGCCATTGCGCTTGCTTGTCGTCCTGATATCTTAATCTGTGATGAACCTAC
AACAGCGCTTGATGTTACCATTCAAGCACAAATCATTGATTTGTTGAAATCATTGCAACAAGAGTATCAATTCACTACTA
TTTTTATCACCCACGACCTTGGAGTGGTAGCAAGTATTGCGGATAAAGTTGCCGTTATGTATGCTGGAGAAATCGTCGAG
TATGGTACAGTAGAAGACGTCTTTTATGATCCACGTCATCCTTATACTTGGAGCTTGTTATCAAGCTTGCCACAGTTGGC
AGATGATAAAGGAGAGCTTTACTCTATTCCTGGCACACCGCCGTCTCTTTATTCACACTTGCAAGGAGATGCTTTCGCTC
TTCGTTCAGATTATGCGATGGAAATTGATTTTGAGGAAAAACCACCTCAAATCTATGTATCAGATACACATTGGGCAAAA
ACATGGTTGCTTCATGAAAATGCTCCAAAAGTGAATAAACCTGCTGTTATTGATGATTTACATGAAAAAATTAGCTCAAA
AATGGGTTTTGCTCATTTAGACGCTTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: F9P7H5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	86.402	99.437	0.859
amiE	Streptococcus thermophilus LMG 18311	84.986	99.437	0.845
amiE	Streptococcus thermophilus LMD-9	84.986	99.437	0.845
oppD	Streptococcus mutans UA159	55.65	99.718	0.555