Detailed information NTG0066562

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SCSC_RS03990
• Genome accession: NZ_AP014647
• Coordinates: 804940..807168 (+)
• Length: 742 a.a.
• NCBI ID: WP_037565577.1
• Uniprot ID: -
• Organism: Streptococcus constellatus subsp. constellatus strain CCUG 24889
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 799940..812168

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCSC_RS03965 (SCSC_0821)	rpmG	800800..800949 (+)	150	WP_003024746.1	50S ribosomal protein L33	-
SCSC_RS03970 (SCSC_0822)	secG	800989..801222 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
SCSC_RS03975 (SCSC_0823)	rnr	801315..803654 (+)	2340	WP_006269566.1	ribonuclease R	-
SCSC_RS03980 (SCSC_0824)	smpB	803617..804084 (+)	468	WP_003034458.1	SsrA-binding protein SmpB	-
SCSC_RS03985 (SCSC_0826)	comEA/celA/cilE	804252..804956 (+)	705	WP_006269533.1	helix-hairpin-helix domain-containing protein	Machinery gene
SCSC_RS03990 (SCSC_0827)	comEC/celB	804940..807168 (+)	2229	WP_037565577.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SCSC_RS03995 (SCSC_0828)	-	807248..807736 (+)	489	WP_006269494.1	DUF805 domain-containing protein	-
SCSC_RS04000 (SCSC_0829)	-	807758..807967 (+)	210	WP_022524619.1	hypothetical protein	-
SCSC_RS04005 (SCSC_0830)	-	808412..809398 (+)	987	WP_006269544.1	Gfo/Idh/MocA family oxidoreductase	-
SCSC_RS04010 (SCSC_0831)	-	809423..810076 (+)	654	WP_006269516.1	uracil-DNA glycosylase	-
SCSC_RS04015 (SCSC_0832)	-	810085..810555 (+)	471	WP_006269550.1	8-oxo-dGTP diphosphatase	-
SCSC_RS04020 (SCSC_0833)	-	810567..811841 (+)	1275	WP_006269592.1	dihydroorotase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85433.42 Da
• Isoelectric Point: 10.0339

>NTDB_id=66562 SCSC_RS03990 WP_037565577.1 804940..807168(+) (comEC/celB) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSSWLAWFCFIFLIIRLFVLYSPKKCFTTLMFLACFAAFFFVRREMAEWQTKA
EPSSVRQVAVLPDTIKVNGDSLSFRGKANGQTYQIYYKLKSKEEQLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQAY
LKTQGIYRILKVDQILSSQDRVSFQPFEWLSNWRRKALVFIKRNFPNPMNHYMTGLLFGALETDFDEMSDLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLKLGLTKEMVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLL
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKVVVESSIISLGVLPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
LIFLISPFIKLIQVNFLFEGLENSIRWIANVFGRPIVFGQPSSLLLVVMLLVLAILYDVRKNKKWVILLSLCLAILFFIT
KFPFQNEITMVDVGRGDSLFLRDWKGRNVLIDVGGREEIRTKESWQKRTTKSNAEKTLIPYLKSRGIDTIDTLILTNPNA
DYAGDVIKVVKKFAVKKIFISRSSLNDADFLNKLKETRAFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGAKNSSHSKFLQQIEPAVALISVGKNNQSKSPNQEMIERLNRLNAKIY
RTDERGAIKFSGWTKWQLETVQ

Nucleotide

• Length: 2229 bp

>NTDB_id=66562 SCSC_RS03990 WP_037565577.1 804940..807168(+) (comEC/celB) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGTCACAGTGGATTAAGATATTTCCGATTAAACCAATTTACATTGCTTTCTTACTTGTCTGGCTATATTTTGCAATCTA
TCAAAGTAGCTGGTTGGCTTGGTTTTGTTTTATTTTTCTAATAATCCGTCTTTTTGTCCTTTATTCACCGAAAAAATGTT
TCACAACTTTAATGTTTCTCGCTTGTTTTGCTGCTTTTTTCTTTGTTCGTAGAGAAATGGCAGAGTGGCAAACAAAAGCA
GAACCTTCTTCTGTAAGACAAGTAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCGCTTTCTTTTCGCGGCAA
AGCAAATGGGCAGACTTATCAAATTTACTACAAATTGAAATCAAAAGAAGAACAGTTGGCTTTTCAAAATCTATCCAGTC
TTGTCACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAACGCAATTTTTCTGGTTTTGATTATCAAGCCTAT
CTAAAAACGCAAGGGATTTATCGGATTTTAAAGGTGGATCAAATTTTGTCTAGTCAAGATAGGGTTAGCTTCCAACCGTT
TGAGTGGTTGTCTAACTGGCGAAGAAAGGCATTGGTTTTCATTAAGAGAAATTTTCCAAATCCGATGAATCATTACATGA
CAGGGCTCTTATTTGGCGCATTAGAGACAGATTTTGATGAAATGAGTGATCTTTATTCTAGCTTGGGAATTATTCATTTA
TTTGCGTTATCTGGCATGCAAGTTGGCTTTTTTATGGAAGGATTTCGTAAGTTGCTTTTGAAGCTGGGACTTACGAAGGA
AATGGTTCATAAATGCCAATATCCGTTTTCTTTCTTTTATGCAGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGTT
TAATTCAGAAATTATTGTCGCAACATGGTATCACTAAATTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGCTT
ATGCCATCTTTTCTTTTAACGGCAGGAGGAGTTCTCTCCTGTGCCTATGCTTTTGTTATTAGTGTTATAGATTTTGAAAG
TCTGACTTCTTGGAGAAAAGTTGTGGTAGAGAGTAGTATCATTTCACTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GAGAATTTCAACCTTGGTCTATTTTATTGACATTTGTTTTTTCACTAATTTTTGATATAGTGATGCTACCGGGTTTAACA
CTGATTTTTCTCATTTCACCTTTCATAAAGCTCATTCAAGTAAATTTTCTTTTTGAAGGCTTAGAAAATAGTATTCGTTG
GATAGCAAATGTCTTTGGCAGACCAATCGTTTTTGGGCAACCTAGCTCGCTTTTATTAGTTGTTATGCTGCTTGTACTGG
CTATTTTGTATGATGTTAGAAAAAATAAAAAATGGGTGATATTGCTCAGCTTGTGTCTTGCTATACTATTTTTTATAACT
AAATTTCCTTTTCAAAATGAGATCACAATGGTTGATGTTGGACGGGGAGATAGTCTTTTTTTGAGAGACTGGAAAGGTAG
AAATGTATTGATTGACGTTGGAGGACGTGAAGAAATTAGAACAAAAGAATCTTGGCAAAAACGAACAACTAAATCAAATG
CGGAGAAAACTTTGATTCCTTACCTAAAAAGTCGTGGTATAGATACGATTGATACTCTAATCTTAACAAATCCTAATGCA
GATTATGCGGGAGATGTAATAAAAGTGGTTAAAAAGTTTGCGGTAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAGAGCATTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAGCTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGAGCTAAAAATTCATCACATTCAAAATTTTTACAGCAAATAGAACCGGCAGTTGCACTCATTT
CTGTTGGGAAAAATAACCAATCCAAATCTCCGAATCAAGAAATGATAGAGCGATTGAATCGCTTAAATGCGAAGATTTAT
CGAACAGATGAACGAGGGGCGATCAAGTTTTCAGGATGGACAAAATGGCAATTAGAAACTGTTCAATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (496-578)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.351	100	0.547
comEC/celB	Streptococcus mitis NCTC 12261	54.29	100	0.546
comEC/celB	Streptococcus pneumoniae TIGR4	53.548	100	0.539
comEC/celB	Streptococcus pneumoniae Rx1	52.744	100	0.531
comEC/celB	Streptococcus pneumoniae D39	52.744	100	0.531
comEC/celB	Streptococcus pneumoniae R6	52.744	100	0.531
comEC	Lactococcus lactis subsp. cremoris KW2	46.299	100	0.464