Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SCSC_RS02010 Genome accession   NZ_AP014647
Coordinates   393133..395016 (+) Length   627 a.a.
NCBI ID   WP_003070235.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. constellatus strain CCUG 24889     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 388133..400016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCSC_RS01995 (SCSC_0410) fmt 390139..391074 (+) 936 WP_006270052.1 methionyl-tRNA formyltransferase -
  SCSC_RS02000 (SCSC_0411) rsmB 391064..392377 (+) 1314 WP_003070239.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SCSC_RS02005 (SCSC_0412) - 392396..393136 (+) 741 WP_003028411.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SCSC_RS02010 (SCSC_0413) stkP 393133..395016 (+) 1884 WP_003070235.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SCSC_RS02015 (SCSC_0414) liaF 395272..395970 (+) 699 WP_003070232.1 cell wall-active antibiotics response protein LiaF -
  SCSC_RS02020 (SCSC_0415) - 395967..396962 (+) 996 WP_006270078.1 sensor histidine kinase -
  SCSC_RS02025 (SCSC_0416) - 396964..397596 (+) 633 WP_003070225.1 response regulator transcription factor -
  SCSC_RS02030 (SCSC_0417) - 397643..399043 (+) 1401 WP_006270079.1 Cof-type HAD-IIB family hydrolase -
  SCSC_RS02035 (SCSC_0418) - 399045..399437 (+) 393 WP_022524708.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68065.30 Da        Isoelectric Point: 9.5690

>NTDB_id=66547 SCSC_RS02010 WP_003070235.1 393133..395016(+) (stkP) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QPLENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLISASKPTTPTPIKETV
SSNSKPTTKPKTKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTVAQARSAIETAGLKVGKEKDEYSD
SVKKDSVIRTNPEAGTQRRDGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEHAAGTVVG
QTPAAGSTYDLTSKARITLKVAKSVSSVVMPSYIGSTYEFAYNNLTQVLGIQGANIEKRTVPTAPAGTQANTIIKQTPEA
NQSLDLKSDRIVLYVYEPKTESSSTSESSLQSESSSEKNSPSSSNSSTSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=66547 SCSC_RS02010 WP_003070235.1 393133..395016(+) (stkP) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGATTCAAGTCGGCAAGATATTTGCCGGGCGATATAGAATCATCAAACAAATTGGGCGAGGTGGCATGGCAGATGTTTA
CTTGGCCAAAGATTTGATTTTAGACGGGGAAGAAGTCGCGGTGAAAGTTCTAAGAACGAATTACCAGACGGATCCGATTG
CTGTGGCGCGCTTTCAAAGAGAGGCGCGAGCGATGGCAGACTTGGATCATCCTCATATTGTCCGGATTACCGATATTGGA
GAAGAAGAAGGTCAGCAATATCTAGCAATGGAATATGTGGCTGGGCTTGACTTAAAACGCTATATTAAAGAGCATGCTCC
TTTATCTAATGAAGAAGCGGTTCGGATTATGGGACAAATTCTTTTGGCGATGCGTTTGGCGCATACGCATGGAATTGTTC
ATCGTGATTTGAAGCCACAAAATGTTCTTTTAACTCCAGATGGCGATGCAAAAGTAACGGACTTTGGAATTGCAGTAGCT
TTTGCTGAAACGAGCCTGACGCAAACAAATTCAATGCTGGGATCTGTGCATTATCTATCACCAGAACAAGCGCGTGGTTC
AAAAGCGACCGTTCAAAGCGATATTTACGCTATGGGGATCATTTTCTATGAAATGTTGACAGGACATATCCCTTATGATG
GGGATAGTGCTGTCACAATTGCTTTGCAACATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAATGTGCCA
CAGCCTCTAGAAAATGTAGTCATCAAGGCAACGGCTAAAAAATTAACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCCGCAGATCGCCGAAATGAGAAAAAGTTGGTTTTTGATGATACTGCCAAAGCAGATACCA
AGACGCTTCCTAAAGTGTCACAAAATACCTTAATTTCTGCAAGCAAACCAACTACTCCTACGCCTATAAAAGAAACAGTC
AGTAGTAATTCTAAACCCACAACCAAGCCAAAAACAAAGAAAAAGCGTCGTTTAAGAACGCGTTATAAGGTTCTGTTGTC
GGCAGTAGTTTTAGTGATTGCTGCTCTGGTGGCATTAGTCTATTTGAGTCCGTCAAATGTAAAAATTCCAGACGTTACTG
GAAAAACTGTTGCACAAGCTCGTTCTGCAATTGAAACAGCAGGTTTGAAAGTTGGTAAGGAAAAAGATGAATATAGCGAC
TCTGTCAAAAAGGATTCTGTTATTCGCACCAATCCAGAAGCGGGAACACAGCGTCGCGACGGAAGCACGGTGGATCTGAT
TGTTTCCAAAGGTACAAAAACCTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCGGATGCTATCAACAATCTAGTCC
AAAAATACAAGGTTTCAAAAGGTTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGCATGCGGCTGGAACAGTCGTTGGT
CAAACGCCAGCAGCAGGTAGTACATATGATTTGACTTCAAAAGCTCGTATTACTTTGAAAGTAGCCAAGTCCGTTTCAAG
TGTTGTCATGCCAAGTTATATCGGTTCAACCTATGAATTTGCCTATAACAATTTAACGCAAGTGCTTGGCATTCAAGGTG
CTAATATTGAAAAACGAACGGTTCCAACAGCTCCGGCGGGAACACAAGCAAATACGATTATTAAACAAACGCCAGAAGCA
AATCAGTCCTTGGATTTGAAGAGCGACCGCATTGTCCTATATGTATATGAGCCGAAAACCGAAAGTTCGTCTACATCTGA
AAGTAGTTTGCAATCTGAAAGTAGTTCAGAAAAAAATAGTCCATCGTCTAGTAACTCATCAACTAGTGGTAATGATGGTT
CAAGTTCAAAAACGCCAGACACAAGTGCTAGTGCAAGCAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(436-503)

PASTA domain (PASTA)

(367-430)

PASTA domain (PASTA)

(508-576)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

65.588

93.62

0.614
  stkP Streptococcus pneumoniae D39

65.247

93.62

0.611
  stkP Streptococcus pneumoniae R6

65.247

93.62

0.611
  stkP Streptococcus pneumoniae Rx1

65.077

93.62

0.609
  pknB Streptococcus mutans UA159

58.974

93.301

0.55
  stkP/pknB Streptococcus salivarius strain HSISS4

55.184

95.375

0.526

Multiple sequence alignment