Detailed information NTG0664196

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG368_RS17030
• Genome accession: NZ_CP108643
• Coordinates: 3906780..3907904 (+)
• Length: 374 a.a.
• NCBI ID: WP_030404779.1
• Uniprot ID: A0A6B3QRH4
• Organism: Streptomyces sp. NBC_01124
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3901780..3912904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG368_RS17010 (OG368_16980)	-	3901805..3902635 (+)	831	WP_361670004.1	hypothetical protein	-
OG368_RS17015 (OG368_16985)	-	3902732..3902860 (+)	129	WP_405409921.1	hypothetical protein	-
OG368_RS17020 (OG368_16990)	-	3902953..3904734 (-)	1782	WP_405408520.1	BACON domain-containing protein	-
OG368_RS17025 (OG368_16995)	radA/sms	3905289..3906698 (+)	1410	WP_102932190.1	DNA repair protein RadA	Machinery gene
OG368_RS17030 (OG368_17000)	disA	3906780..3907904 (+)	1125	WP_030404779.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG368_RS17035 (OG368_17005)	-	3907925..3908770 (-)	846	WP_309318655.1	hypothetical protein	-
OG368_RS17040 (OG368_17010)	-	3908929..3909855 (+)	927	WP_125629511.1	A/G-specific adenine glycosylase	-
OG368_RS17045 (OG368_17015)	-	3910154..3910687 (+)	534	WP_003975479.1	SigE family RNA polymerase sigma factor	-
OG368_RS17050 (OG368_17020)	-	3910675..3911352 (+)	678	WP_176154385.1	hypothetical protein	-
OG368_RS17055 (OG368_17025)	cseB	3911478..3912182 (+)	705	WP_102930763.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40084.82 Da
• Isoelectric Point: 5.0058

>NTDB_id=664196 OG368_RS17030 WP_030404779.1 3906780..3907904(+) (disA) [Streptomyces sp. NBC_01124]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVEQMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=664196 OG368_RS17030 WP_030404779.1 3906780..3907904(+) (disA) [Streptomyces sp. NBC_01124]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACGTCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGCGGCAACACGGGCGGTCTGATCGTGC
TGGGCTCCGACAAGACCGTCGAGCAGATGTGCACGGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCGTCCGACCTGTCGAAGATCCTGCGGGCCGGGGTGCAGCTCCTTCC
GGATCCCACCATTCCGACGGAGGAGACCGGTACGCGGCACCGGACCGCCGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TCGTGTCGGTCTCGCAGTCGATGCGGCTGATCGCCCTGTACGTGGACGGGCAGCGGCGGGTGCTGGAGGATTCGGCGGCC
ATTCTGTCGCGGGCCAATCAGGCACTGGCGACCCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCCGCGGTCGCGCAGCGGCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGGCTGCTCGCGCTGCAGTTGGACGAGCTGATCGCC
GGGGTGGAGCCCGAGCGCGAGCTGGTCGTGCGGGACTACGTGCCGGAGCCGACCGCCAAGCGGTCCCGTACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCACGCGGAACTGCTGGAACTGTCGACCGTGGCCCGGGCCCTGGGCTACACCG
GGTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTGCAGACCGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0A6B3QRH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.524	0.447