Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SRT_RS09110 Genome accession   NZ_AP014612
Coordinates   1874931..1875653 (-) Length   240 a.a.
NCBI ID   WP_128833864.1    Uniprot ID   A0A1L7LLT0
Organism   Streptococcus troglodytae strain TKU 31     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1869931..1880653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SRT_RS09085 (SRT_18600) sufU 1869956..1870399 (-) 444 WP_128833859.1 Fe-S cluster assembly sulfur transfer protein SufU -
  SRT_RS09090 (SRT_18610) - 1870386..1871615 (-) 1230 WP_128833860.1 cysteine desulfurase -
  SRT_RS09095 (SRT_18620) sufD 1871620..1872882 (-) 1263 WP_128833861.1 Fe-S cluster assembly protein SufD -
  SRT_RS09100 (SRT_18630) sufC 1872920..1873690 (-) 771 WP_128833862.1 Fe-S cluster assembly ATPase SufC -
  SRT_RS09105 (SRT_18640) rgpG 1873765..1874925 (-) 1161 WP_128833863.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  SRT_RS09110 (SRT_18650) mecA 1874931..1875653 (-) 723 WP_128833864.1 adaptor protein MecA Regulator
  SRT_RS09115 (SRT_18660) - 1875744..1876589 (-) 846 WP_002262750.1 undecaprenyl-diphosphate phosphatase -
  SRT_RS09120 (SRT_18670) - 1876653..1878554 (-) 1902 WP_161940053.1 DUF2207 domain-containing protein -
  SRT_RS09125 (SRT_18680) - 1878708..1880261 (+) 1554 WP_128833865.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28055.70 Da        Isoelectric Point: 4.2887

>NTDB_id=66192 SRT_RS09110 WP_128833864.1 1874931..1875653(-) (mecA) [Streptococcus troglodytae strain TKU 31]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFKTLEETMREKGDAAALDKLAEIEKREEEKTQQEQGETKEKRDYVHFVLDFPNIQQA
ISFAKTVDYDVEASELFKESDAYHMTVLLNLKDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGIQLIRADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=66192 SRT_RS09110 WP_128833864.1 1874931..1875653(-) (mecA) [Streptococcus troglodytae strain TKU 31]
ATGGAAATGAAACAAATCAGCGAAACAACGCTAAAAATTACCATCAGTATGGAAGATTTAGAAGAAAGAGGTATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAAACGGAAGAATTTTTCTATACTGTTATGGATGAGCTGGACCTGCCTGAAAATT
TCAAGGACAGTGGAATGCTGAGCTTTCGCGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAATCAGAAATC
AATAAAAATCTTAATTTAGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCCCCAGAGGATTTCTTTAAGACCTT
GGAGGAAACCATGCGTGAAAAGGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAATTGAGAAAAGAGAAGAAGAGAAGA
CTCAGCAAGAACAAGGTGAAACTAAGGAAAAGAGGGACTACGTTCACTTTGTGCTGGACTTTCCTAATATTCAGCAAGCC
ATAAGTTTTGCCAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TCTGCTTAATCTCAAAGATAAACCTGATTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGCATTCAGCTTATTAGGGCAGATGCTCTGCAAGAATTACAGATGATTGGA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L7LLT0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

97.083

100

0.971
  mecA Streptococcus thermophilus LMD-9

57.787

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.377

100

0.583
  mecA Streptococcus pneumoniae Rx1

48.98

100

0.5
  mecA Streptococcus pneumoniae D39

48.98

100

0.5
  mecA Streptococcus pneumoniae R6

48.98

100

0.5
  mecA Streptococcus pneumoniae TIGR4

48.98

100

0.5

Multiple sequence alignment